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1M01
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BU of 1m01 by Molmil
Wildtype Streptomyces plicatus beta-hexosaminidase in complex with product (GlcNAc)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:J Williams, S, Mark, B.L, Vocadlo, D.J, James, M.N.G, Withers, S.G.
Deposit date:2002-06-11
Release date:2003-01-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
5TEB
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BU of 5teb by Molmil
Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1
Descriptor: Recognition of Peronospora parasitica 1
Authors:Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B.
Deposit date:2016-09-20
Release date:2017-02-01
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.796 Å)
Cite:Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7ZYJ
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BU of 7zyj by Molmil
Leishmania tarentolae proteasome 20S subunit in complex with compound 2
Descriptor: Proteasome alpha 1 subunit, putative, Proteasome alpha 5 subunit, ...
Authors:Srinivas, H.
Deposit date:2022-05-24
Release date:2022-09-28
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
J.Med.Chem., 65, 2022
3QAS
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BU of 3qas by Molmil
Structure of Undecaprenyl Diphosphate synthase
Descriptor: Undecaprenyl pyrophosphate synthase
Authors:Cao, R, Oldfield, E.
Deposit date:2011-01-11
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Applying Molecular Dynamics Simulations to Identify Rarely Sampled Ligand-bound Conformational States of Undecaprenyl Pyrophosphate Synthase, an Antibacterial Target.
Chem.Biol.Drug Des., 77, 2011
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