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NMR structure of the Streptococcus pyogenes NAD+-glycohydrolase translocation domain
Descriptor:	ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase
Authors:	Velarde, J.J, Piai, A, Chou, J.J, Wessels, M.
Deposit date:	2020-07-22
Release date:	2021-07-28
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	Structure of the Streptococcus pyogenes NAD + Glycohydrolase Translocation Domain and Its Essential Role in Toxin Binding to Oropharyngeal Keratinocytes. J.Bacteriol., 204, 2022

Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor
Descriptor:	Focal adhesion kinase 1, N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide
Authors:	Vajdos, F, Marr, E.
Deposit date:	2008-01-17
Release date:	2008-04-01
Last modified:	2017-10-25
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. Cancer Res., 68, 2008

6-Amino-4-(pyrimidin-4-yl)pyridones: Novel Glycogen Synthase Kinase-3 Inhibitors
Descriptor:	4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one, Glycogen synthase kinase-3 beta
Authors:	Pandit, J.
Deposit date:	2010-12-21
Release date:	2011-06-15
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	6-amino-4-(pyrimidin-4-yl)pyridones: novel glycogen synthase kinase-3β inhibitors Bioorg.Med.Chem.Lett., 21, 2011