8XCL
 
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2MHM
 | | Solution structure of cytochrome c Y67H | | Descriptor: | Cytochrome c iso-1, HEME C | | Authors: | Lan, W.X, Wang, Z.H, Yang, Z.Z, Ying, T.L, Wu, H.M, Tan, X.S, Cao, C.Y, Huang, Z.X. | | Deposit date: | 2013-11-26 | | Release date: | 2014-10-29 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Cytochrome c Y67H Mutant to Function as a Peroxidase
Plos One, 9, 2014
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8WR3
 | | Cryo-EM structure of lysosomal protein LYCHOS | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Wang, Z.H, Qian, H.W. | | Deposit date: | 2023-10-12 | | Release date: | 2025-01-15 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis for cholesterol sensing of LYCHOS and its interaction with indoxyl sulfate.
Nat Commun, 16, 2025
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5GGZ
 | | Crystal structure of novel inhibitor bound with Hsp90 | | Descriptor: | Heat shock protein HSP 90-alpha, [2,4-bis(oxidanyl)-5-propan-2-yl-phenyl]-(2-ethoxy-7,8-dihydro-5~{H}-pyrido[4,3-d]pyrimidin-6-yl)methanone | | Authors: | Chen, T.T, Li, J, Xu, Y.C. | | Deposit date: | 2016-06-16 | | Release date: | 2017-03-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.015 Å) | | Cite: | Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90
J. Med. Chem., 59, 2016
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9J3Z
 | | Cryo-EM structure of lysosome cholesterol sencing protein in L state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal cholesterol signaling protein,G protein-coupled receptor 155 fusion protein | | Authors: | Qian, H.W, Wang, Z.H. | | Deposit date: | 2024-08-08 | | Release date: | 2025-04-02 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis for cholesterol sensing of LYCHOS and its interaction with indoxyl sulfate.
Nat Commun, 16, 2025
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9J40
 | | Cryo-EM structure of lysosome cholesterol sencing protein complex | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-SULFOOXY-1H-INDOLE, ... | | Authors: | Qian, H.W, Wang, Z.H. | | Deposit date: | 2024-08-08 | | Release date: | 2025-04-02 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for cholesterol sensing of LYCHOS and its interaction with indoxyl sulfate.
Nat Commun, 16, 2025
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9J3X
 | | Cryo-EM structure of lysosome cholesterol sencing protein LYCHOS in Tight-state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Qian, H.W, Wang, Z.H. | | Deposit date: | 2024-08-08 | | Release date: | 2025-04-02 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for cholesterol sensing of LYCHOS and its interaction with indoxyl sulfate.
Nat Commun, 16, 2025
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8GYX
 | | Cryo-EM structure of human CEPT1 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION | | Authors: | Qian, H.W, Wang, Z.H. | | Deposit date: | 2022-09-24 | | Release date: | 2023-03-22 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Nat Commun, 14, 2023
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8GYW
 | | Cryo-EM structure of human CEPT1 complexed with CDP-choline | | Descriptor: | Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM | | Authors: | Qian, H.W, Wang, Z.H. | | Deposit date: | 2022-09-24 | | Release date: | 2023-03-22 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Nat Commun, 14, 2023
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5YRQ
 | | Crystal structure of Rad5 and Rev1 | | Descriptor: | DNA repair protein RAD5,DNA repair protein REV1 | | Authors: | Chen, Z.C, Zhou, C.Y. | | Deposit date: | 2017-11-09 | | Release date: | 2019-03-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | Involvement of budding yeast Rad5 in translesion DNA synthesis through physical interaction with Rev1.
Nucleic Acids Res., 44, 2016
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