6K51
 
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6K50
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1BQH
 | | MURINE CD8AA ECTODOMAIN FRAGMENT IN COMPLEX WITH H-2KB/VSV8 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (BETA-2-MICROGLOBULIN ), PROTEIN (CD8A OR LYT2 OR LYT-2), ... | | 著者 | Wang, J.H, Reinherz, E.L, Kern, P.S, Chang, H.C. | | 登録日 | 1998-08-16 | | 公開日 | 1998-08-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb.
Immunity, 9, 1998
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2ATP
 | | Crystal structure of a CD8ab heterodimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, ... | | 著者 | Chang, H.C, Tan, K, Ouyang, J, Parisini, E, Liu, J.H, Le, Y, Wang, X, Reinherz, E.L, Wang, J.H. | | 登録日 | 2005-08-25 | | 公開日 | 2005-12-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Mutational Analyses of a CD8alphabeta Heterodimer and Comparison with the CD8alphaalpha Homodimer.
Immunity, 23, 2005
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1T0P
 | | Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, Intercellular adhesion molecule-3, ... | | 著者 | Song, G, Yang, Y.T, Liu, J.H, Shimaoko, M, Springer, T.A, Wang, J.H. | | 登録日 | 2004-04-12 | | 公開日 | 2005-03-08 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1NEZ
 | | The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Liu, Y, Xiong, Y, Naidenko, O.V, Liu, J.H, Zhang, R, Joachimiak, A, Kronenberg, M, Cheroutre, H, Reinherz, E.L, Wang, J.H. | | 登録日 | 2002-12-12 | | 公開日 | 2003-04-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Crystal Structure of a TL/CD8alphaalpha Complex at 2.1 A resolution: Implications for modulation of T cell activation and memory
Immunity, 18, 2003
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1P53
 | | The Crystal Structure of ICAM-1 D3-D5 fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Intercellular adhesion molecule-1 | | 著者 | Yang, Y, Jun, C.D, Liu, J.H, Zhang, R, Jochimiak, A, Springer, T.A, Wang, J.H. | | 登録日 | 2003-04-24 | | 公開日 | 2004-05-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Structural basis for dimerization of ICAM-1 on the cell surface.
Mol.Cell, 14, 2004
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1ZA4
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1MJN
 | | Crystal Structure of the intermediate affinity aL I domain mutant | | 分子名称: | Integrin alpha-L, MAGNESIUM ION | | 著者 | Shimaoka, M, Xiao, T, Liu, J.H, Yang, Y.T, Dong, Y.C, Jun, C.D, McCormack, A, Zhang, R.G, Wang, J.H, Springer, T.A. | | 登録日 | 2002-08-28 | | 公開日 | 2003-01-28 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of the alphaL I Domain and its Complex with ICAM-1 reveal a Shape-shifting Pathway for Integrin Regulation
Cell(Cambridge,Mass.), 112, 2003
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3COO
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7R7Z
 | | Crystal structure of QW9-HLA-B*5301 specific T Cell Receptor, C3 | | 分子名称: | Alpha chain of C3 TCR, Beta chain of C3 TCR, HEXAETHYLENE GLYCOL, ... | | 著者 | Li, X.L, Tan, K.M, Xu, S.T, Ng, R, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.286 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
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7R7Y
 | | Crystal structure of HLA-B*5701 complex with an HIV-1 Gag-derived epitope QW9 S3T variant | | 分子名称: | Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, GLYCEROL, ... | | 著者 | Li, X.L, Ng, R, Tan, K.M, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
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7R80
 | | Crystal structure of C3 TCR complex with QW9-bound HLA-B*5301 | | 分子名称: | Alpha chain of C3 TCR, Beta Chain of C3 TCR, Beta-2-microglobulin, ... | | 著者 | Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
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7R7X
 | | Crystal structure of HLA-B*5701 complex with an HIV-1 Gag-derived epitope QW9 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, GLN-ALA-SER-GLN-GLU-VAL-LYS-ASN-TRP, ... | | 著者 | Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
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7R7V
 | | Crystal structure of HLA-B*5301 complex with an HIV-1 Gag-derived epitope QW9 | | 分子名称: | Beta-2-microglobulin, GLN-ALA-SER-GLN-GLU-VAL-LYS-ASN-TRP, GLYCEROL, ... | | 著者 | Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
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7R7W
 | | Crystal structure of HLA-B*5301 complex with an HIV-1 Gag-derived epitope QW9 S3T variant | | 分子名称: | Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, MHC class I antigen | | 著者 | Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
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2VE6
 | | Crystal structure of a Murine MHC class I H2-Db molecule in complex with a photocleavable peptide | | 分子名称: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, SENDAI VIRUS EPITOPE RESIDUES 324-332 MODIFIED AT P7 | | 著者 | Grotenbreg, G.M, Roan, N.R, Guillen, E, Meijers, R, Wang, J.H, Bell, G.W, Starnbach, M.N, Ploegh, H.L. | | 登録日 | 2007-10-17 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery of Cd8+ T Cell Epitopes in Chlamydia Trachomatis Infection Through Use of Caged Class I Mhc Tetramers.
Proc.Natl.Acad.Sci.USA, 105, 2008
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4O33
 | | Crystal Structure of human PGK1 3PG and terazosin(TZN) ternary complex | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone | | 著者 | Li, X.L, Finci, L.I, Wang, J.H. | | 登録日 | 2013-12-18 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
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4O3F
 | | Crystal Structure of mouse PGK1 3PG and terazosin(TZN) ternary complex | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone | | 著者 | Li, X.L, Finci, I.L, Wang, J.H. | | 登録日 | 2013-12-18 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.106 Å) | | 主引用文献 | Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
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4O6X
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7DKG
 | | Influenza H5N1 nucleoprotein (truncated) in complex with nucleotides | | 分子名称: | Nucleoprotein, RNA (5'-R(P*(OMU)P*(OMU)P*(OMU))-3') | | 著者 | Tang, Y.S, Xu, S, Chen, Y.W, Wang, J.H, Shaw, P.C. | | 登録日 | 2020-11-24 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction.
Nucleic Acids Res., 49, 2021
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7DXP
 | | Influenza H5N1 nucleoprotein in complex with nucleotides | | 分子名称: | 1,2-ETHANEDIOL, Nucleoprotein, RNA (5'-R(P*(OMU)P*(OMU)P*(OMU)P*(OMU))-3') | | 著者 | Tang, Y.S, Xu, S, Chen, Y.W, Wang, J.H, Shaw, P.C. | | 登録日 | 2021-01-19 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction.
Nucleic Acids Res., 49, 2021
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1VSC
 | | VCAM-1 | | 分子名称: | VASCULAR CELL ADHESION MOLECULE-1 | | 著者 | Wang, J, Stehle, T, Osborn, L. | | 登録日 | 1995-04-27 | | 公開日 | 1996-06-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction.
Proc.Natl.Acad.Sci.USA, 92, 1995
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1JL4
 | | CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE | | 分子名称: | H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ... | | 著者 | Wang, J.-H, Meijers, R, Reinherz, E.L. | | 登録日 | 2001-07-15 | | 公開日 | 2001-09-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1QA9
 | | Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors | | 分子名称: | HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN | | 著者 | Wang, J.-H, Smolyar, A, Tan, K, Liu, J.-H, Kim, M, Sun, Z.J, Wagner, G, Reinherz, E.L. | | 登録日 | 1999-04-13 | | 公開日 | 1999-04-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell(Cambridge,Mass.), 97, 1999
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