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NRIP1_133 / RIP140 SxxLxxLL motif coregulator peptide with agonist GW1929 and PPARg LBD
Descriptor:	(2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Nuclear receptor-interacting protein 1, Peroxisome proliferator-activated receptor gamma
Authors:	Nemetchek, M.D, Voss, A.H, McClelland, L.J, Hughes, T.S.
Deposit date:	2024-07-29
Release date:	2024-08-14
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	NRIP1_133 / RIP140 SxxLxxLL motif coregulator peptide with agonist GW1929 and PPARg LBD To Be Published

Crystal structure of PPAR gamma in complex with Mediator of RNA polymerase II transcription subunit 1
Descriptor:	(2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Mediator of RNA polymerase II transcription subunit 1, Peroxisome proliferator-activated receptor gamma
Authors:	Mou, T.C, Chrisman, I.M, Hughes, T.S, Sprang, S.R.
Deposit date:	2018-04-27
Release date:	2019-05-01
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	A structural mechanism of nuclear receptor biased agonism. Proc.Natl.Acad.Sci.USA, 119, 2022

Crystal structure of PPAR gamma in complex with CREB-binding protein and agonist GW1929
Descriptor:	(2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CREB-binding protein, Peroxisome proliferator-activated receptor gamma
Authors:	Nemetchek, M.D, Sprang, S.R, Hughes, T.S.
Deposit date:	2021-07-23
Release date:	2022-08-03
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	A structural mechanism of nuclear receptor biased agonism. Proc.Natl.Acad.Sci.USA, 119, 2022