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7K45
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BU of 7k45 by Molmil
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-14
Release date:2020-10-07
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 370, 2020
7K4N
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BU of 7k4n by Molmil
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), ...
Authors:Tortorici, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-15
Release date:2020-10-07
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 370, 2020
7M55
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BU of 7m55 by Molmil
B6 Fab fragment bound to the MERS-CoV spike stem helix peptide
Descriptor: B6 antigen binding fragment (Fab) heavy chain, B6 antigen binding fragment (Fab) light chain, GLYCEROL, ...
Authors:Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-03-22
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7M5E
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BU of 7m5e by Molmil
MERS-CoV S bound to the broadly neutralizing B6 Fab fragment (C3 refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
Authors:Sauer, M.M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-03-23
Release date:2021-05-26
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7M53
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BU of 7m53 by Molmil
B6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide
Descriptor: B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ...
Authors:Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-03-22
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7M51
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BU of 7m51 by Molmil
B6 Fab fragment bound to the OC43 spike stem helix peptide
Descriptor: B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ...
Authors:Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-03-22
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7M52
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BU of 7m52 by Molmil
B6 Fab fragment bound to the HKU4 spike stem helix peptide
Descriptor: B6 antigen-binding (Fab) fragment heavy chain, B6 antigen-binding (Fab) fragment light chain, GLYCEROL, ...
Authors:Sauer, M.M, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-03-22
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7JZL
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BU of 7jzl by Molmil
SARS-CoV-2 spike in complex with LCB1 (2RBDs open)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCB1, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Science, 370, 2020
7JZN
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BU of 7jzn by Molmil
SARS-CoV-2 spike in complex with LCB3 (2RBDs open)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCB3, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Science, 370, 2020
7JZM
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BU of 7jzm by Molmil
SARS-CoV-2 spike in complex with LCB3 (local refinement of the RBD and LCB3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, LCB3, Spike glycoprotein
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Science, 370, 2020
7JZU
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BU of 7jzu by Molmil
SARS-CoV-2 spike in complex with LCB1 (local refinement of the RBD and LCB1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, LCB1, Spike glycoprotein
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-02
Release date:2020-09-23
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.
Science, 370, 2020
7TN0
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BU of 7tn0 by Molmil
SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:McCallum, M, Czudnochowski, N, Nix, J.C, Croll, T.I, SSGCID, Dillen, J.R, Snell, G, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-01-20
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement.
Science, 375, 2022
7TXZ
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BU of 7txz by Molmil
Nipah Virus attachment (G) glycoprotein ectodomain in complex with nAH1.3 neutralizing antibody Fab fragment (local refinement of the distal region)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, Z.Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-02-10
Release date:2022-03-09
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Architecture and antigenicity of the Nipah virus attachment glycoprotein.
Science, 375, 2022
7TY0
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BU of 7ty0 by Molmil
Nipah Virus attachment (G) glycoprotein ectodomain in complex with nAH1.3 neutralizing antibody Fab fragment (local refinement of the stalk region)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, Z.Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-02-10
Release date:2022-03-09
Last modified:2022-04-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Architecture and antigenicity of the Nipah virus attachment glycoprotein.
Science, 375, 2022
7TPK
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BU of 7tpk by Molmil
SARS-CoV-2 E406W mutant RBD - Local Refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1
Authors:Addetia, A, Veesler, D.
Deposit date:2022-01-25
Release date:2023-02-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 E406W mutant RBD - Local Refinement
To Be Published
7KI6
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BU of 7ki6 by Molmil
Structure of the HeV F glycoprotein in complex with the 1F5 neutralizing antibody
Descriptor: 1F5 Fab light chain, 1F5 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dang, H.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2020-10-23
Release date:2021-05-05
Last modified:2021-06-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins.
Nat.Struct.Mol.Biol., 28, 2021
7KI4
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BU of 7ki4 by Molmil
Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody
Descriptor: 12B2 Fab light chain, 12B2 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dang, H.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2020-10-23
Release date:2021-05-05
Last modified:2021-05-26
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins.
Nat.Struct.Mol.Biol., 28, 2021
4IL7
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BU of 4il7 by Molmil
Crystal structure of A223 C-terminal domain, a structural protein from sulfolobus turreted icosahedral virus (STIV)
Descriptor: Putative uncharacterized protein
Authors:Sendamarai, A.K, Lawrence, C.M.
Deposit date:2012-12-29
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography.
Proc.Natl.Acad.Sci.USA, 110, 2013
8VWP
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BU of 8vwp by Molmil
Langya Virus attachment (G) glycoprotein with K85L/L86K mutation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment (G) protein
Authors:Gibson, C.G, McCallum, M.M, Veesler, D.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-02
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
5HX2
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BU of 5hx2 by Molmil
In vitro assembled star-shaped hubless T4 baseplate
Descriptor: Baseplate wedge protein gp10, Baseplate wedge protein gp53, Baseplate wedge protein gp6, ...
Authors:Yap, M.L, Klose, T, Fokine, A, Rossmann, M.G.
Deposit date:2016-01-29
Release date:2016-03-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Role of bacteriophage T4 baseplate in regulating assembly and infection.
Proc.Natl.Acad.Sci.USA, 113, 2016
4HEM
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BU of 4hem by Molmil
Llama vHH-02 binder of ORF49 (RBP) from lactococcal phage TP901-1
Descriptor: Anti-baseplate TP901-1 Llama vHH 02, BPP
Authors:Desmyter, A, Spinelli, S, Farenc, C, Blangy, S, Bebeacua, C, van Sinderen, D, Mahony, J, Cambillau, C.
Deposit date:2012-10-04
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Viral infection modulation and neutralization by camelid nanobodies
Proc.Natl.Acad.Sci.USA, 110, 2013
4HEP
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BU of 4hep by Molmil
Complex of lactococcal phage TP901-1 with a llama vHH (vHH17) binder (nanobody)
Descriptor: BPP, SULFATE ION, vHH17 domain
Authors:Desmyter, A, Spinelli, S, Farenc, C, Blangy, S, Bebeacua, C, van Sinderen, D, Mahony, J, Cambillau, C.
Deposit date:2012-10-04
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Viral infection modulation and neutralization by camelid nanobodies
Proc.Natl.Acad.Sci.USA, 110, 2013
6XSS
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BU of 6xss by Molmil
CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900
Descriptor: C4_nat_HFuse-7900
Authors:Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G.
Deposit date:2020-07-16
Release date:2020-12-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
7M7W
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BU of 7m7w by Molmil
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody S2H97 Fab heavy chain, Monoclonal antibody S2H97 Fab light chain, ...
Authors:Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
Deposit date:2021-03-29
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
6XNS
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BU of 6xns by Molmil
C3_crown-05
Descriptor: C3_crown-05
Authors:Bick, M.J, Hsia, Y, Sankaran, B, Baker, D.
Deposit date:2020-07-04
Release date:2020-12-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021

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數據於2024-05-15公開中

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