1H43
| R210E N-TERMINAL LOBE HUMAN LACTOFERRIN | 分子名称: | CARBONATE ION, FE (III) ION, LACTOFERRIN | 著者 | Peterson, N.A, Arcus, V.L, Anderson, B.F, Jameson, G.B, Tweedie, J.W, Baker, E.N. | 登録日 | 2002-10-02 | 公開日 | 2002-11-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | "Dilysine Trigger" in Transferrins Probed by Mutagenesis of Lactoferrin: Crystal Structures of the R210G, R210E, and R210L Mutants of Human Lactoferrin Biochemistry, 41, 2002
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1H44
| R210L N-TERMINAL LOBE HUMAN LACTOFERRIN | 分子名称: | CARBONATE ION, FE (III) ION, LACTOFERRIN | 著者 | Peterson, N.A, Arcus, V.L, Anderson, B.F, Jameson, G.B, Tweedie, J.W, Baker, E.N. | 登録日 | 2002-10-03 | 公開日 | 2002-11-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | "Dilysine Trigger" in Transferrins Probed by Mutagenesis of Lactoferrin: Crystal Structures of the R210G, R210E, and R210L Mutants of Human Lactoferrin Biochemistry, 41, 2002
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1HPG
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1I80
| CRYSTAL STRUCTURE OF M. TUBERCULOSIS PNP IN COMPLEX WITH IMINORIBITOL, 9-DEAZAHYPOXANTHINE AND PHOSPHATE ION | 分子名称: | 9-DEAZAHYPOXANTHINE, IMINORIBITOL, PHOSPHATE ION, ... | 著者 | Shi, W, Basso, L.A, Tyler, P.C, Furneaux, R.H, Blanchard, J.S, Almo, S.C, Schramm, V.L. | 登録日 | 2001-03-12 | 公開日 | 2001-08-01 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces. Biochemistry, 40, 2001
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4JOS
| Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Francisella philomiragia ATCC 25017 (Target NYSGRC-029335) | 分子名称: | 1,2-ETHANEDIOL, ADENINE, Adenosylhomocysteine nucleosidase, ... | 著者 | Sampathkumar, P, Schramm, V.L, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-03-18 | 公開日 | 2013-04-03 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Francisella philomiragia ATCC 25017 (Target NYSGRC-029335) to be published
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4KEN
| Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J. | 登録日 | 2013-04-25 | 公開日 | 2014-10-29 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Complexed structures of AmpC beta-lactamase To be Published
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4KG5
| Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefotaxime | 分子名称: | Beta-lactamase, CEFOTAXIME, C3' cleaved, ... | 著者 | Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J. | 登録日 | 2013-04-28 | 公開日 | 2014-10-29 | 最終更新日 | 2018-09-19 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Complexed structures of AmpC beta-lactamase To be Published
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4KG6
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4KG2
| Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime | 分子名称: | Beta-lactamase, CEFOTAXIME, C3' cleaved, ... | 著者 | Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J. | 登録日 | 2013-04-28 | 公開日 | 2014-10-29 | 最終更新日 | 2018-09-19 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Complexed structures of AmpC beta-lactamase To be Published
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4MAZ
| The Structure of MalL mutant enzyme V200S from Bacillus subtilus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... | 著者 | Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. | 登録日 | 2013-08-18 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
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4MB1
| The Structure of MalL mutant enzyme G202P from Bacillus subtilus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Oligo-1,6-glucosidase 1 | 著者 | Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. | 登録日 | 2013-08-19 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
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4M8U
| The Structure of MalL mutant enzyme V200A from Bacillus subtilus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | 著者 | Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. | 登録日 | 2013-08-13 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
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4M56
| The Structure of Wild-type MalL from Bacillus subtilis | 分子名称: | D-glucose, GLYCEROL, Oligo-1,6-glucosidase 1, ... | 著者 | Hobbs, J.K, Jiao, W, Easter, A.D, Parker, E.J, Schipper, L.A, Arcus, V.L. | 登録日 | 2013-08-08 | 公開日 | 2013-10-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates. Acs Chem.Biol., 8, 2013
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1XBA
| Crystal structure of apo syk tyrosine kinase domain | 分子名称: | Tyrosine-protein kinase SYK | 著者 | Atwell, S, Adams, J.M, Badger, J, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Nienaber, V.L, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | 登録日 | 2004-08-30 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. J.Biol.Chem., 279, 2004
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1XBB
| Crystal structure of the syk tyrosine kinase domain with Gleevec | 分子名称: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Tyrosine-protein kinase SYK | 著者 | Nienaber, V.L, Atwell, S, Adams, J.M, Badger, J, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | 登録日 | 2004-08-30 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | A Novel Mode of Gleevec Binding Is Revealed by the Structure of Spleen Tyrosine Kinase J.Biol.Chem., 279, 2004
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1XBC
| Crystal structure of the syk tyrosine kinase domain with Staurosporin | 分子名称: | STAUROSPORINE, Tyrosine-protein kinase SYK | 著者 | Badger, J, Atwell, S, Adams, J.M, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Nienaber, V.L, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | 登録日 | 2004-08-30 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase J.Biol.Chem., 279, 2004
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1XOI
| Human Liver Glycogen Phosphorylase A complexed with Chloroindoloyl glycine amide | 分子名称: | 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID{[CYCLOPENTYL-(2-HYDROXY-ETHYL)-CARBAMOYL]-METHYL}-AMIDE, Glycogen phosphorylase, liver form, ... | 著者 | Wright, S.W, Rath, V.L, Gibbs, E.M, Treadway, J.L. | 登録日 | 2004-10-06 | 公開日 | 2005-04-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization. Bioorg.Med.Chem.Lett., 15, 2005
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1Y6Q
| Cyrstal structure of MTA/AdoHcy nucleosidase complexed with MT-DADMe-ImmA | 分子名称: | (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, CHLORIDE ION, MTA/SAH nucleosidase | 著者 | Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L. | 登録日 | 2004-12-06 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. J.Biol.Chem., 280, 2005
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1YT4
| Crystal structure of TEM-76 beta-lactamase at 1.4 Angstrom resolution | 分子名称: | Beta-lactamase TEM | 著者 | Thomas, V.L, Golemi-Kotra, D, Kim, C, Vakulenko, S.B, Mobashery, S, Shoichet, B.K. | 登録日 | 2005-02-09 | 公開日 | 2005-07-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM beta-Lactamase. Biochemistry, 44, 2005
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1ZOS
| Structure of 5'-methylthionadenosine/S-Adenosylhomocysteine nucleosidase from S. pneumoniae with a transition-state inhibitor MT-ImmA | 分子名称: | (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase | 著者 | Shi, W, Singh, V, Zhen, R, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. | 登録日 | 2005-05-13 | 公開日 | 2006-04-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae. Biochemistry, 45, 2006
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1ZSQ
| Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate | 分子名称: | 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Myotubularin-related protein 2 | 著者 | Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E. | 登録日 | 2005-05-25 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVR
| Crystal Structure of MTMR2 in complex with phosphatidylinositol 3,5-bisphosphate | 分子名称: | (1S)-2-(1-HYDROXYBUTOXY)-1-{[(HYDROXY{[(2R,3S,5R,6S)-2,4,6-TRIHYDROXY-3,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTYRATE, 1,2-ETHANEDIOL, Myotubularin-related protein 2 | 著者 | Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E. | 登録日 | 2005-06-02 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase Proc.Natl.Acad.Sci.Usa, 103, 2006
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2A0Y
| Structure of human purine nucleoside phosphorylase H257D mutant | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | 著者 | Murkin, A.S, Shi, W, Schramm, V.L. | 登録日 | 2005-06-17 | 公開日 | 2006-06-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Neighboring group participation in the transition state of human purine nucleoside phosphorylase. Biochemistry, 46, 2007
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1ZVM
| Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase | 分子名称: | ADP-ribosyl cyclase 1, SULFATE ION | 著者 | Shi, W, Yang, T, Almo, S.C, Schramm, V.L, Sauve, A. | 登録日 | 2005-06-02 | 公開日 | 2006-06-06 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of human CD38: Cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase To be Published
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2A0W
| Structure of human purine nucleoside phosphorylase H257G mutant | 分子名称: | 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, Purine nucleoside phosphorylase, SULFATE ION | 著者 | Murkin, A.S, Shi, W, Schramm, V.L. | 登録日 | 2005-06-17 | 公開日 | 2006-06-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Neighboring group participation in the transition state of human purine nucleoside phosphorylase. Biochemistry, 46, 2007
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