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5COV
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Structure and mechanism of a eukaryal nick-sealing RNA ligase K170M+Mn
分子名称: MANGANESE (II) ION, Naegleria gruberi RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2015-07-20
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
5COT
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BU of 5cot by Molmil
Structure and mechanism of a eukaryal nick-sealing RNA ligase
分子名称: ADENOSINE MONOPHOSPHATE, Naegleria gruberi RNA ligase, UNKNOWN ATOM OR ION
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2015-07-20
公開日2015-10-28
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
5COU
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Structure and mechanism of a eukaryal nick-sealing RNA ligase K170M+ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Naegleria gruberi RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2015-07-20
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
6VT4
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Naegleria gruberi RNA ligase R149A mutant apo
分子名称: RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VTE
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BU of 6vte by Molmil
Naegleria gruberi RNA Ligase K170M mutant with AMP and Mn
分子名称: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT8
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BU of 6vt8 by Molmil
Naegleria gruberi RNA ligase E312A mutant with AMP and Mn
分子名称: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT3
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Naegleria gruberi RNA ligase K326A mutant apo
分子名称: RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.844 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VTD
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Naegleria gruberi RNA ligase R149A mutant with ATP and Mn
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT5
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Naegleria gruberi RNA ligase R4a K121A mutant apo
分子名称: RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VTF
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BU of 6vtf by Molmil
Naegleria gruberi RNA ligase with PPi
分子名称: PYROPHOSPHATE 2-, RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT6
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BU of 6vt6 by Molmil
Naegleria gruberi RNA ligase K170A mutant with ATP and Mn
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VTG
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BU of 6vtg by Molmil
Naegleria gruberi RNA ligase E227A mutant apo
分子名称: RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT0
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BU of 6vt0 by Molmil
Naegleria gruberi RNA ligase K170A mutant apo
分子名称: RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VTB
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BU of 6vtb by Molmil
Naegleria gruberi RNA ligase K326A mutant with ATP and Mn
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.547 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT9
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BU of 6vt9 by Molmil
Naegleria gruberi RNA ligase E227A mutant with ATP and Mn
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT1
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BU of 6vt1 by Molmil
Naegleria gruberi RNA ligase D172A mutant apo
分子名称: ADENOSINE MONOPHOSPHATE, RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
7LD5
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BU of 7ld5 by Molmil
polynucleotide phosphorylase
分子名称: MAGNESIUM ION, Polyribonucleotide nucleotidyltransferase, poly-A RNA fragment
著者Goldgur, Y, Shuman, S, De La Cruz, M.J, Ghosh, S, Unciuleac, M.-C.
登録日2021-01-12
公開日2021-06-30
最終更新日2022-11-30
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase.
Rna, 27, 2021
6NHX
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BU of 6nhx by Molmil
mycobacterial DNA ligase D complexed with ATP and MES
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent DNA ligase
著者Shuman, S, Unciuleac, M, Goldgur, Y.
登録日2018-12-24
公開日2019-02-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates.
J. Biol. Chem., 294, 2019
6NHZ
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BU of 6nhz by Molmil
mycobacterial DNA ligase D complexed with ATP and Mg
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent DNA ligase, MAGNESIUM ION
著者Shuman, S, Unciuleac, M, Goldgur, Y.
登録日2018-12-24
公開日2019-02-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates.
J. Biol. Chem., 294, 2019
5TT6
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BU of 5tt6 by Molmil
T4 RNA Ligase 1 (K99M)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, T4 RNA ligase 1
著者Goldgur, Y, Unciuleac, M.-C, Shuman, S.H.
登録日2016-11-01
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TT5
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BU of 5tt5 by Molmil
Escherichia coli LigA (K115M) in complex with NAD+
分子名称: DNA ligase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Goldgur, Y, Unciuleac, M.-C, Shuman, S.H.
登録日2016-11-01
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5E7P
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BU of 5e7p by Molmil
Crystal Structure of MSMEG_0858 (Uniprot A0QQS4), a AAA ATPase.
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein Cdc48, GLYCEROL, ...
著者Unciulac-Carp, M, Smith, P, Shuman, S.
登録日2015-10-12
公開日2016-08-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.507 Å)
主引用文献Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858).
J.Bacteriol., 198, 2016
6PPR
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BU of 6ppr by Molmil
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and DNA
分子名称: ATP-dependent DNA helicase (UvrD/REP), DNA (70-MER), IRON/SULFUR CLUSTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PPJ
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BU of 6ppj by Molmil
Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP
分子名称: ATP-dependent DNA helicase (UvrD/REP), IRON/SULFUR CLUSTER, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-07
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PPU
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BU of 6ppu by Molmil
Cryo-EM structure of AdnAB-AMPPNP-DNA complex
分子名称: ATP-dependent DNA helicase (UvrD/REP), DNA (29-MER), IRON/SULFUR CLUSTER, ...
著者Jia, N, Unciuleac, M, Shuman, S, Patel, D.J.
登録日2019-07-08
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Proc.Natl.Acad.Sci.USA, 116, 2019

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