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2Y2F
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BU of 2y2f by Molmil
Crystal structure of Yersinia pestis YopH in complex with an aminooxy- containing platform compound for inhibitor design
Descriptor: PROTEIN-TYROSINE PHOSPHATASE YOPH, [4-[3-(DIFLUORO-PHOSPHONO-METHYL)PHENYL]PHENYL]METHOXYAZANIUM
Authors:Lountos, G.T, Bahta, M, Dyas, B, Ulrich, R.G, Waugh, D.S, Burke, T.R.
Deposit date:2010-12-14
Release date:2011-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia Pestis Outer Protein H (Yoph) Phosphatase.
J.Med.Chem., 54, 2011
2YDU
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BU of 2ydu by Molmil
Crystal structure of YopH in complex with 3-(1,1-dioxido-3- oxoisothiazolidin-5-yl)benzaldeyde
Descriptor: 3-[(2S)-1,1-DIOXIDO-4-OXOTETRAHYDROTHIOPHEN-2-YL]BENZALDEHYDE, OUTER PROTEIN H PHOSPHATASE
Authors:Lountos, G.T, Kim, S.E, Bahta, M, Ulrich, R.G, Waugh, D.S, Burke, T.R.
Deposit date:2011-03-24
Release date:2011-11-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Isothiazolidinone (Izd) as a Phosphoryl Mimetic in Inhibitors of the Yersinia Pestis Protein Tyrosine Phosphatase Yoph.
Acta Crystallogr.,Sect.D, 67, 2011
6D3F
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BU of 6d3f by Molmil
Crystal Structure of the PTP epsilon D2 domain
Descriptor: Receptor-type tyrosine-protein phosphatase epsilon
Authors:Lountos, G.T, Raran-Kurussi, S, Zhao, B.M, Dyas, B.K, Austin, B.P, Burke Jr, T.R, Ulrich, R.G, Waugh, D.S.
Deposit date:2018-04-16
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design.
Acta Crystallogr D Struct Biol, 74, 2018
6D4F
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BU of 6d4f by Molmil
Crystal structure of PTP epsilon D2 domain (A455N/V457Y/E597D)
Descriptor: PENTAETHYLENE GLYCOL, Receptor-type tyrosine-protein phosphatase epsilon
Authors:Lountos, G.T, Raran-Kurussi, S, Zhao, B.M, Dyas, B.K, Austin, B.P, Burke Jr, T.R, Ulrich, R.G, Waugh, D.S.
Deposit date:2018-04-18
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design.
Acta Crystallogr D Struct Biol, 74, 2018
6D4D
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BU of 6d4d by Molmil
Crystal structure of the PTP epsilon D1 domain
Descriptor: Receptor-type tyrosine-protein phosphatase epsilon
Authors:Lountos, G.T, Raran-Kurussi, S, Zhao, B.M, Dyas, B.K, Austin, B.P, Burke Jr, T.R, Ulrich, R.G, Waugh, D.S.
Deposit date:2018-04-18
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.765 Å)
Cite:High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design.
Acta Crystallogr D Struct Biol, 74, 2018
7QQB
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BU of 7qqb by Molmil
Crystal structure of the envelope glycoprotein complex of Puumala virus in complex with the scFv fragment of the broadly neutralizing human antibody ADI-42898
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, GLYCEROL, ...
Authors:Serris, A, Rey, F.A, Guardado-Calvo, P.
Deposit date:2022-01-07
Release date:2023-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody.
Sci Transl Med, 15, 2023

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