1QTS
 
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1QTP
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2G30
 | | beta appendage of AP2 complexed with ARH peptide | | Descriptor: | 16-mer peptide from Low density lipoprotein receptor adapter protein 1, AP-2 complex subunit beta-1, peptide sequence AAF | | Authors: | Edeling, M.A, Collins, B.M, Traub, L.M, Owen, D.J. | | Deposit date: | 2006-02-17 | | Release date: | 2006-03-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Molecular Switches Involving the AP-2 beta2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly
Dev.Cell, 10, 2006
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3I2W
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1KYD
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1KY6
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1KYF
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1KY7
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1KYU
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7Z5C
 | | Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit | | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | Authors: | Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. | | Deposit date: | 2022-03-09 | | Release date: | 2022-05-11 | | Method: | ELECTRON MICROSCOPY (4.16 Å) | | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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3G9H
 | | Crystal structure of the C-terminal mu homology domain of Syp1 | | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Suppressor of yeast profilin deletion | | Authors: | Reider, A, Barker, S, Mishra, S, Im, Y.J, Maldonado-Baez, L, Hurley, J, Traub, L, Wendland, B. | | Deposit date: | 2009-02-13 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.
Embo J., 28, 2009
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3G9G
 | | Crystal Structure of the N-terminal EFC/F-BAR domain of Syp1 | | Descriptor: | Suppressor of yeast profilin deletion | | Authors: | Reider, A, Barker, S, Mishra, S, Im, Y.J, Maldonado-Baez, L, Hurley, J, Traub, L, Wendland, B. | | Deposit date: | 2009-02-13 | | Release date: | 2009-09-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.
Embo J., 28, 2009
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1UTC
 | | Clathrin terminal domain complexed with TLPWDLWTT | | Descriptor: | AMPHIPHYSIN, CLATHRIN HEAVY CHAIN | | Authors: | Miele, A.E, Evans, P.R, Owen, D.J. | | Deposit date: | 2003-12-08 | | Release date: | 2004-02-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Nat. Struct. Mol. Biol., 11, 2004
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5JP2
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5M5R
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5M61
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5M5T
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5M5V
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5M5U
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5M5S
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7OIT
 | | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form) | | Descriptor: | AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL | | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | Deposit date: | 2021-05-12 | | Release date: | 2022-06-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OHO
 | | Crystal structure of AP2 FCHO2 chimera | | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... | | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | Deposit date: | 2021-05-11 | | Release date: | 2022-06-01 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OG1
 | | AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 | | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | Deposit date: | 2021-05-05 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OIQ
 | | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) | | Descriptor: | AP-2 complex subunit mu, F-BAR domain only protein 2 | | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | Deposit date: | 2021-05-12 | | Release date: | 2022-06-01 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OHI
 | | FCHO1-peptide-AP2 alpha ear complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AP-2 complex subunit alpha-2, F-BAR domain only protein 1, ... | | Authors: | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | Deposit date: | 2021-05-11 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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