1SLY
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![BU of 1sly by Molmil](/molmil-images/mine/1sly) | COMPLEX OF THE 70-KDA SOLUBLE LYTIC TRANSGLYCOSYLASE WITH BULGECIN A | Descriptor: | 4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE, 70-KDA SOLUBLE LYTIC TRANSGLYCOSYLASE | Authors: | Thunnissen, A.M.W.H, Kalk, K.H, Rozeboom, H.J, Dijkstra, B.W. | Deposit date: | 1995-08-02 | Release date: | 1996-08-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymatic mechanism. Biochemistry, 34, 1995
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1DM2
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![BU of 1dm2 by Molmil](/molmil-images/mine/1dm2) | HUMAN CYCLIN-DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR HYMENIALDISINE | Descriptor: | 1,2-ETHANEDIOL, 4-(5-AMINO-4-OXO-4H-PYRAZOL-3-YL)-2-BROMO-4,5,6,7-TETRAHYDRO-3AH-PYRROLO[2,3-C]AZEPIN-8-ONE, CYCLIN-DEPENDENT KINASE 2 | Authors: | Thunnissen, A.M, Kim, S.-H. | Deposit date: | 1999-12-13 | Release date: | 2000-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent. Chem.Biol., 7, 2000
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5CLO
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![BU of 5clo by Molmil](/molmil-images/mine/5clo) | |
5CLN
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![BU of 5cln by Molmil](/molmil-images/mine/5cln) | |
4X19
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![BU of 4x19 by Molmil](/molmil-images/mine/4x19) | |
4X1C
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![BU of 4x1c by Molmil](/molmil-images/mine/4x1c) | |
4U5P
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![BU of 4u5p by Molmil](/molmil-images/mine/4u5p) | Crystal structure of native RhCC (YP_702633.1) from Rhodococcus jostii RHA1 at 1.78 Angstrom | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... | Authors: | Poddar, H, Rozeboom, H.J, Thunnissen, A.M.W.H. | Deposit date: | 2014-07-25 | Release date: | 2015-02-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | Functional and structural characterization of an unusual cofactor-independent oxygenase. Biochemistry, 54, 2015
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4U5R
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![BU of 4u5r by Molmil](/molmil-images/mine/4u5r) | |
1CKP
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![BU of 1ckp by Molmil](/molmil-images/mine/1ckp) | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B | Descriptor: | 1,2-ETHANEDIOL, PROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2), PURVALANOL B | Authors: | Gray, N.S, Thunnissen, A.M.W.H, Schultz, P.G, Kim, S.H. | Deposit date: | 1998-07-14 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science, 281, 1998
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1OXT
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![BU of 1oxt by Molmil](/molmil-images/mine/1oxt) | Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus | Descriptor: | ABC transporter, ATP binding protein | Authors: | Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M. | Deposit date: | 2003-04-03 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus:
nucleotide-free and nucleotide-bound conformations J.Mol.Biol., 330, 2003
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4ESF
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![BU of 4esf by Molmil](/molmil-images/mine/4esf) | |
4ESB
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![BU of 4esb by Molmil](/molmil-images/mine/4esb) | Crystal structure of PadR-like transcriptional regulator (BC4206) from Bacillus cereus strain ATCC 14579 | Descriptor: | GLYCEROL, SULFATE ION, Transcriptional regulator, ... | Authors: | Fibriansah, G, Kovacs, A.T, Kuipers, O.P, Thunnissen, A.M.W.H. | Deposit date: | 2012-04-23 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily. Plos One, 7, 2012
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3L6H
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![BU of 3l6h by Molmil](/molmil-images/mine/3l6h) | Crystal structure of lactococcal OpuAC in its closed-liganded conformation complexed with glycine betaine | Descriptor: | Betaine ABC transporter permease and substrate binding protein, CHLORIDE ION, TRIMETHYL GLYCINE | Authors: | Berntsson, R.P.A, Wolters, J.C, Gul, N, Karasawa, A, Thunnissen, A.M.W.H, Slotboom, D.J, Poolman, B. | Deposit date: | 2009-12-23 | Release date: | 2010-05-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA. Plos One, 5, 2010
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3L6G
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![BU of 3l6g by Molmil](/molmil-images/mine/3l6g) | Crystal structure of lactococcal OpuAC in its open conformation | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Betaine ABC transporter permease and substrate binding protein | Authors: | Berntsson, R.P.A, Wolters, J.C, Gul, N, Karasawa, A, Thunnissen, A.M.W.H, Slotboom, D.J, Poolman, B. | Deposit date: | 2009-12-23 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA. Plos One, 5, 2010
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1IIG
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![BU of 1iig by Molmil](/molmil-images/mine/1iig) | STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE | Descriptor: | 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J. | Deposit date: | 2001-04-23 | Release date: | 2001-05-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes. Proteins, 10, 1991
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1IIH
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![BU of 1iih by Molmil](/molmil-images/mine/1iih) | STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHOGLYCERATE | Descriptor: | 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J. | Deposit date: | 2001-04-23 | Release date: | 2001-05-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes. Proteins, 10, 1991
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1OXS
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![BU of 1oxs by Molmil](/molmil-images/mine/1oxs) | Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus | Descriptor: | ABC transporter, ATP binding protein, IODIDE ION | Authors: | Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M. | Deposit date: | 2003-04-03 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus:
nucleotide-free and nucleotide-bound conformations J.Mol.Biol., 330, 2003
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1OXU
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![BU of 1oxu by Molmil](/molmil-images/mine/1oxu) | Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus | Descriptor: | ABC transporter, ATP binding protein, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M. | Deposit date: | 2003-04-03 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations J.Mol.Biol., 330, 2003
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1OXV
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![BU of 1oxv by Molmil](/molmil-images/mine/1oxv) | Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus | Descriptor: | ABC transporter, ATP binding protein, IODIDE ION, ... | Authors: | Verdon, G, Albers, S.V, Dijkstra, B.W, Driessen, A.J, Thunnissen, A.M. | Deposit date: | 2003-04-03 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus:
nucleotide-free and nucleotide-bound conformations J.Mol.Biol., 330, 2003
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3H8G
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![BU of 3h8g by Molmil](/molmil-images/mine/3h8g) | Bestatin complex structure of leucine aminopeptidase from Pseudomonas putida | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, BICARBONATE ION, Cytosol aminopeptidase, ... | Authors: | Kale, A, Dijkstra, B.W, Sonke, T, Thunnissen, A.M.W.H. | Deposit date: | 2009-04-29 | Release date: | 2010-04-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity. J.Mol.Biol., 398, 2010
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3H8E
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3H8F
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![BU of 3h8f by Molmil](/molmil-images/mine/3h8f) | High pH native structure of leucine aminopeptidase from Pseudomonas putida | Descriptor: | BICARBONATE ION, Cytosol aminopeptidase, MANGANESE (II) ION, ... | Authors: | Kale, A, Dijkstra, B.W, Sonke, T, Thunnissen, A.M.W.H. | Deposit date: | 2009-04-29 | Release date: | 2010-04-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity. J.Mol.Biol., 398, 2010
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5LH9
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![BU of 5lh9 by Molmil](/molmil-images/mine/5lh9) | |
2PIC
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![BU of 2pic by Molmil](/molmil-images/mine/2pic) | |
2PI8
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![BU of 2pi8 by Molmil](/molmil-images/mine/2pi8) | Crystal structure of E. coli MltA with bound chitohexaose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane-bound lytic murein transglycosylase A, PHOSPHATE ION | Authors: | van Straaten, K.E, Barends, T.R.M, Dijkstra, B.W, Thunnissen, A.M.W.H. | Deposit date: | 2007-04-13 | Release date: | 2007-05-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage J.Biol.Chem., 282, 2007
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