5AO1
 
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5AO2
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5AO0
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5AO3
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5AO4
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6XU1
 | | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | 登録日 | 2020-01-17 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
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6YOM
 | | Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | 著者 | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | 登録日 | 2020-04-14 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
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2NPI
 | | Clp1-ATP-Pcf11 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein CLP1, ... | | 著者 | Noble, C.G, Beuth, B, Taylor, I.A. | | 登録日 | 2006-10-27 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor
Nucleic Acids Res., 35, 2007
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6QEY
 | | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties | | 分子名称: | ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION | | 著者 | Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A. | | 登録日 | 2019-01-09 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties.
Nucleic Acids Res., 47, 2019
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6SAI
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6S7X
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6SSM
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6S7Y
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6SSK
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6SSL
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6SA9
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6SSJ
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4UX5
 | | Structure of DNA complex of PCG2 | | 分子名称: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | | 著者 | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | | 登録日 | 2014-08-19 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains.
Nucleic Acids Res., 43, 2015
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2BF0
 | | crystal structure of the rpr of pcf11 | | 分子名称: | CALCIUM ION, PCF11 | | 著者 | Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A. | | 登録日 | 2004-12-02 | | 公開日 | 2005-01-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
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2ASB
 | | Structure of a Mycobacterium tuberculosis NusA-RNA complex | | 分子名称: | Transcription elongation protein nusA, ribosomal RNA (5'- GAACUCAAUAG -3') | | 著者 | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | | 登録日 | 2005-08-23 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
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2ATW
 | | Structure of a Mycobacterium tuberculosis NusA-RNA complex | | 分子名称: | Transcription elongation protein nusA, ribosomal RNA (5'- AGAACUCAAUAG -3') | | 著者 | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | | 登録日 | 2005-08-26 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
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3BP9
 | | Structure of B-tropic MLV capsid N-terminal domain | | 分子名称: | GLYCEROL, Gag protein, ISOPROPYL ALCOHOL | | 著者 | Gulnahar, M.B, Dodding, M.P, Goldstone, D.C, Haire, L.F, Stoye, J.P, Taylor, I.A. | | 登録日 | 2007-12-18 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation
J.Mol.Biol., 376, 2008
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1G6G
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2X1A
 | | Structure of Rna15 RRM with RNA bound (G) | | 分子名称: | 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15 | | 著者 | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | | 登録日 | 2010-01-06 | | 公開日 | 2010-02-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
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2X1F
 | | Structure of Rna15 RRM with bound RNA (GU) | | 分子名称: | 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15 | | 著者 | Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A. | | 登録日 | 2010-01-06 | | 公開日 | 2010-02-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
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