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8G4E
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BU of 8g4e by Molmil
Green Fluorescence Protein imaged on a cryo-EM imaging scaffold
Descriptor: RCG-10 - Cryo-EM imaging scaffold subunit B fused to DARPin, Superfolder Green Fluorescent Protein
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4H
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BU of 8g4h by Molmil
KRAS G13C complex with GDP imaged on a cryo-EM imaging scaffold
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G3K
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BU of 8g3k by Molmil
Cryo-EM imaging scaffold subunits A and B used to display KRAS G12C complex with GDP
Descriptor: Cob_adeno_trans domain-containing protein, Cryo-EM imaging scaffold subunit B with DARPin - RCG-33
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-08
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4F
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BU of 8g4f by Molmil
KRAS G12V complex with GDP imaged on a cryo-EM imaging scaffold
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-09
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G42
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BU of 8g42 by Molmil
KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
Deposit date:2023-02-08
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
3J70
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BU of 3j70 by Molmil
Model of gp120, including variable regions, in complex with CD4 and 17b
Descriptor: Envelope glycoprotein gp120, T-cell surface glycoprotein CD4, envelope glycoprotein gp41, ...
Authors:Rasheed, M, Bettadapura, R, Bajaj, C.
Deposit date:2014-04-22
Release date:2015-08-26
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.
Structure, 23, 2015
4WXI
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BU of 4wxi by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR trans-N-{(1S)-1-[4-(3-amino-2H-indazol-6-yl)pyridin-2-yl]-2-phenylethyl}-4-(aminomethyl)cyclohexanecarboxamide
Descriptor: 1,2-ETHANEDIOL, COAGULATION FACTOR XI, LIGHT CHAIN, ...
Authors:Wei, A.
Deposit date:2014-11-13
Release date:2015-01-28
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Pyridine and pyridinone-based factor XIa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015

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