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6BS9
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BU of 6bs9 by Molmil
Stage III sporulation protein AB (SpoIIIAB)
Descriptor: SULFATE ION, Stage III sporulation protein AB
Authors:Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A.
Deposit date:2017-12-01
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis.
J. Struct. Biol., 202, 2018
6DCS
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BU of 6dcs by Molmil
Stage III sporulation protein AF (SpoIIIAF)
Descriptor: SULFATE ION, Stage III sporulation protein AF
Authors:Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A.
Deposit date:2018-05-08
Release date:2018-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis.
J. Struct. Biol., 204, 2018
6ZTG
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BU of 6ztg by Molmil
Spor protein DedD
Descriptor: Cell division protein DedD
Authors:Pazos, M, Peters, K, Boes, A, Safaei, Y, Kenward, C, Caveney, N.A, Laguri, C, Breukink, E, Strynadka, N.C.J, Simorre, J.P, Terrak, M, Vollmer, W.
Deposit date:2020-07-20
Release date:2020-11-11
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli.
Mbio, 11, 2020
6XFJ
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BU of 6xfj by Molmil
Crystal structure of the type III secretion pilotin InvH
Descriptor: CADMIUM ION, CHLORIDE ION, SODIUM ION, ...
Authors:Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J.
Deposit date:2020-06-15
Release date:2020-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods.
Structure, 29, 2021
5WD7
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BU of 5wd7 by Molmil
Structure of a bacterial polysialyltransferase in complex with fondaparinux
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, SULFATE ION, SiaD
Authors:Worrall, L.J, Lizak, C, Strynadka, N.C.J.
Deposit date:2017-07-04
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.
Sci Rep, 7, 2017
5WCN
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BU of 5wcn by Molmil
Structure of a bacterial polysialyltransferase in complex with CDP
Descriptor: CYTIDINE-5'-DIPHOSPHATE, SULFATE ION, SiaD
Authors:Worrall, L.J, Lizak, C, Strynadka, N.C.J.
Deposit date:2017-06-30
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.
Sci Rep, 7, 2017
1ERM
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BU of 1erm by Molmil
X-RAY CRYSTAL STRUCTURE OF TEM-1 BETA LACTAMASE IN COMPLEX WITH A DESIGNED BORONIC ACID INHIBITOR (1R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL)ETHANE BORONIC ACID
Descriptor: 1(R)-1-ACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID, TEM-1 BETA-LACTAMASE
Authors:Ness, S, Martin, R, Kindler, A.M, Paetzel, M, Gold, M, Jones, J.B, Strynadka, N.C.J.
Deposit date:2000-04-06
Release date:2000-05-10
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based design guides the improved efficacy of deacylation transition state analogue inhibitors of TEM-1 beta-Lactamase(,).
Biochemistry, 39, 2000
6DV6
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BU of 6dv6 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state
Descriptor: Protein InvG
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DUZ
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BU of 6duz by Molmil
Structure of the periplasmic domains of PrgH and PrgK from the assembled Salmonella type III secretion injectisome needle complex
Descriptor: Lipoprotein PrgK, Protein PrgH
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DZ8
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BU of 6dz8 by Molmil
Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (S75C)
Descriptor: Penicillin-binding protein 4, ZINC ION
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2018-07-03
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 FromStaphylococcus aureus.
Front Microbiol, 9, 2018
5WC8
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BU of 5wc8 by Molmil
Structure of a bacterial polysialyltransferase at 2.75 Angstrom resolution
Descriptor: BROMIDE ION, SiaD
Authors:Worrall, L.J, Lizak, C, Strynadka, N.C.J.
Deposit date:2017-06-29
Release date:2017-08-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.
Sci Rep, 7, 2017
5WC6
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BU of 5wc6 by Molmil
Structure of a bacterial polysialyltransferase at 2.2 Angstrom resolution
Descriptor: SULFATE ION, SiaD
Authors:Worrall, L.J, Lizak, C, Strynadka, N.C.J.
Deposit date:2017-06-29
Release date:2017-08-02
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.
Sci Rep, 7, 2017
1KN9
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BU of 1kn9 by Molmil
CRYSTAL STRUCTURE OF A BACTERIAL SIGNAL PEPTIDASE APO-ENZYME, IMPLICATIONS FOR SIGNAL PEPTIDE BINDING AND THE SER-LYS DYAD MECHANISM.
Descriptor: Signal peptidase I
Authors:Paetzel, M, Dalbey, R.E, Strynadka, N.C.J.
Deposit date:2001-12-18
Release date:2002-01-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
J.Biol.Chem., 277, 2002
7TC5
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BU of 7tc5 by Molmil
All Phe-Azurin variant - F15Y
Descriptor: Azurin, COPPER (II) ION, NITRATE ION, ...
Authors:Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
Deposit date:2021-12-22
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
7TC6
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BU of 7tc6 by Molmil
All Phe-Azurin variant - F15W
Descriptor: Azurin, COPPER (II) ION, NITRATE ION
Authors:Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
Deposit date:2021-12-22
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
6W5Q
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BU of 6w5q by Molmil
Structure of the globular C-terminal domain of P. aeruginosa LpoP
Descriptor: Peptidoglycan synthase activator LpoP, SULFATE ION, TRIETHYLENE GLYCOL
Authors:Caveney, N.A, Robb, C.S, Simorre, J.P, Strynadka, N.C.J.
Deposit date:2020-03-13
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa.
Structure, 28, 2020
7JLR
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BU of 7jlr by Molmil
Crystal structure of Bacillus subtilis UppS in complex with JPD447
Descriptor: 7-(azepan-1-yl)-5-ethyl-3-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine, Isoprenyl transferase
Authors:Workman, S.D, Strynadka, N.C.J.
Deposit date:2020-07-30
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7JLM
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BU of 7jlm by Molmil
Crystal structure of Bacillus subtilis UppS in complex with MAC-0547630
Descriptor: 7-(azepan-1-yl)-3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidine, CITRIC ACID, Isoprenyl transferase
Authors:Workman, S.D, Strynadka, N.C.J.
Deposit date:2020-07-29
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7JLI
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BU of 7jli by Molmil
Crystal structure of Bacillus subtilis UppS
Descriptor: DI(HYDROXYETHYL)ETHER, Isoprenyl transferase
Authors:Workman, S.D, Strynadka, N.C.J.
Deposit date:2020-07-29
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7JLJ
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BU of 7jlj by Molmil
Crystal structure of Bacillus subtilis UppS in complex with clomiphene
Descriptor: Clomifene, Isoprenyl transferase
Authors:Workman, S.D, Strynadka, N.C.J.
Deposit date:2020-07-29
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
J.Med.Chem., 64, 2021
7UZ2
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BU of 7uz2 by Molmil
Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-fluoro-valienide.
Descriptor: (1R,2S,3R,4R)-5-fluoro-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, Beta-galactosidase
Authors:Danby, P.M, Jeong, A, Sim, L, Sweeney, R.P, Wardman, J.F, Geissner, A, Worrall, L.J, Strynadka, N.C.J, Withers, S.G.
Deposit date:2022-05-08
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors.
Angew.Chem.Int.Ed.Engl., 62, 2023
7UZ1
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BU of 7uz1 by Molmil
Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-bromo-valienide.
Descriptor: (1R,2S,3R,4R)-5-bromo-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Beta-galactosidase
Authors:Danby, P.M, Jeong, A, Sim, L, Sweeney, R.P, Wardman, J.F, Karimi, R, Geissner, A, Worrall, L.J, Strynadka, N.C.J, Withers, S.G.
Deposit date:2022-05-08
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors.
Angew.Chem.Int.Ed.Engl., 62, 2023
6XFK
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BU of 6xfk by Molmil
Crystal structure of the type III secretion system pilotin-secretin complex InvH-InvG
Descriptor: SULFATE ION, Type 3 secretion system pilotin, Type 3 secretion system secretin
Authors:Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J.
Deposit date:2020-06-15
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods.
Structure, 29, 2021
6XFU
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BU of 6xfu by Molmil
PmtCD peptide exporter basket domain
Descriptor: ABC transporter ATP-binding protein, THIOCYANATE ION
Authors:Zeytuni, N, Strynadka, N.C.J, Alexander, J.A.N.
Deposit date:2020-06-16
Release date:2020-10-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
2DRJ
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BU of 2drj by Molmil
Xray structure of alpha-2,3/8-sialyltransferase CstII F91Y mutant
Descriptor: Alpha-2,3/8-sialyltransferase, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, ISOPROPYL ALCOHOL
Authors:Chiu, C.P.C, Strynadka, N.C.J.
Deposit date:2006-06-09
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:High-throughput screening methodology for the directed evolution of glycosyltransferases
Nat.Methods, 3, 2006

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