1DT1
 
 | | THERMUS THERMOPHILUS CYTOCHROME C552 SYNTHESIZED BY ESCHERICHIA COLI | | 分子名称: | CYTOCHROME C552, HEME C | | 著者 | Fee, J.A, Chen, Y, Hill, M.J, Gomez-Moran, E, Loehr, T, Ai, J, Thony-Meyer, L, Williams, P.A, Stura, E, Sridhar, V, McRee, D.E. | | 登録日 | 2000-01-10 | | 公開日 | 2000-02-18 | | 最終更新日 | 2021-03-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Integrity of thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: biochemical, spectral, and structural characterization of the recombinant protein.
Protein Sci., 9, 2000
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3M1B
 | | Crystal structure of human FcRn with a dimeric peptide inhibitor | | 分子名称: | Beta-2-microglobulin, DIMERIC PEPTIDE INHIBITOR, IgG receptor FcRn large subunit p51 | | 著者 | Mezo, A.R, Sridhar, V, Badger, J, Sakorafas, P, Nienaber, V. | | 登録日 | 2010-03-04 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
J.Biol.Chem., 285, 2010
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3M17
 | | Crystal structure of human FcRn with a monomeric peptide inhibitor | | 分子名称: | Beta-2-microglobulin, IgG receptor FcRn large subunit p51, monomeric peptide inhibitor | | 著者 | Mezo, A.R, Sridhar, V, Badger, J, Sakorafas, P, Nienaber, V. | | 登録日 | 2010-03-04 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | X-ray crystal structures of monomeric and dimeric peptide inhibitors in complex with the human neonatal Fc receptor, FcRn.
J.Biol.Chem., 285, 2010
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1Z68
 | | Crystal Structure Of Human Fibroblast Activation Protein alpha | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Aertgeerts, K, Levin, I, Shi, L, Prasad, G.S, Zhang, Y, Kraus, M.L, Salakian, S, Snell, G.P, Sridhar, V, Wijnands, R, Tennant, M.G. | | 登録日 | 2005-03-21 | | 公開日 | 2005-04-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.
J.Biol.Chem., 280, 2005
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4E79
 | | Structure of LpxD from Acinetobacter baumannii at 2.66A resolution (P4322 form) | | 分子名称: | UDP-3-O-acylglucosamine N-acyltransferase | | 著者 | Badger, J, Chie-Leon, B, Logan, C, Sridhar, V, Sankaran, B, Zwart, P.H, Nienaber, V. | | 登録日 | 2012-03-16 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
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4E75
 | | Structure of LpxD from Acinetobacter baumannii at 2.85A resolution (P21 form) | | 分子名称: | UDP-3-O-acylglucosamine N-acyltransferase | | 著者 | Badger, J, Chie-Leon, B, Logan, C, Sridhar, V, Sankaran, B, Zwart, P.H, Nienaber, V. | | 登録日 | 2012-03-16 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure determination of LpxD from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 69, 2013
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4E6U
 | | Structure of LpxA from Acinetobacter baumannii at 1.4A resolution (P63 form) | | 分子名称: | 1,2-ETHANEDIOL, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, SULFATE ION | | 著者 | Badger, J, Chie-Leon, B, Logan, C, Sridhar, V, Sankaran, B, Zwart, P.H, Nienaber, V. | | 登録日 | 2012-03-16 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
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4E6T
 | | Structure of LpxA from Acinetobacter baumannii at 1.8A resolution (P212121 form) | | 分子名称: | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, CITRATE ANION | | 著者 | Badger, J, Chie-Leon, B, Logan, C, Sridhar, V, Sankaran, B, Zwart, P.H, Nienaber, V. | | 登録日 | 2012-03-15 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 68, 2012
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5UOY
 | | Crystal structure of human PDE1B catalytic domain in complex with inhibitor 16j (6-(4-Methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one) | | 分子名称: | 6-[(4-methoxyphenyl)methyl]-9-[(oxan-4-yl)methyl]-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ... | | 著者 | Cedervall, E.P, Allerston, C.K, Xu, R, Sridhar, V, Barker, R, Aertgeerts, K. | | 登録日 | 2017-02-01 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J. Med. Chem., 60, 2017
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5UWF
 | | Crystal structure of human PDE10A in complex with inhibitor 16d | | 分子名称: | 9-[(1S)-2,2-difluorocyclopropane-1-carbonyl]-6-[(4-methoxyphenyl)methyl]-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Xu, R, Cedervall, E.P, Sridhar, V, Barker, R, Aertgeerts, K. | | 登録日 | 2017-02-21 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J. Med. Chem., 60, 2017
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5UP0
 | | Crystal structure of human PDE1B catalytic domain in complex with inhibitor 3 (6-(4-chlorobenzyl)-8,9,10,11-tetrahydrobenzo[4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one) | | 分子名称: | 6-[(4-chlorophenyl)methyl]-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ... | | 著者 | Cedervall, E.P, Allerston, C.K, Xu, R, Sridhar, V, Barker, R, Aertgeerts, K. | | 登録日 | 2017-02-01 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J. Med. Chem., 60, 2017
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3BH1
 | | Crystal structure of protein DIP2346 from Corynebacterium diphtheriae | | 分子名称: | GLYCEROL, UPF0371 protein DIP2346 | | 著者 | Patskovsky, Y, Sridhar, V, Bonanno, J.B, Gilmore, M, Iizuka, M, Groshong, C, Gheyi, T, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-11-27 | | 公開日 | 2007-12-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structure of protein DIP2346 from Corynebacterium diphtheriae.
To be Published
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3B5M
 | | Crystal structure of conserved uncharacterized protein from Rhodopirellula baltica | | 分子名称: | SULFATE ION, Uncharacterized protein | | 著者 | Patskovsky, Y, Bonanno, J.B, Sridhar, V, Rutter, M, Powell, A, Maletic, M, Rodgers, R, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-10-26 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Crystal Structure of Conserved Uncharacterized Protein from Rhodopirellula baltica.
To be Published
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3BMA
 | | Crystal structure of D-alanyl-lipoteichoic acid synthetase from Streptococcus pneumoniae R6 | | 分子名称: | D-alanyl-lipoteichoic acid synthetase, GLYCEROL, SULFATE ION | | 著者 | Patskovsky, Y, Sridhar, V, Bonanno, J.B, Smith, D, Rutter, M, Iizuka, M, Koss, J, Bain, K, Gheyi, T, Wasserman, S.R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Crystal Structure of probable D-Alanyl-Lipoteichoic Acid Synthetase from Streptococcus pneumoniae.
To be Published
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1L7E
 | | Crystal Structure of R. rubrum Transhydrogenase Domain I with Bound NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, nicotinamide nucleotide Transhydrogenase, subunit alpha 1 | | 著者 | Prasad, G.S, Wahlberg, M, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | | 登録日 | 2002-03-14 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structures of Transhydrogenase Domain I
with and without Bound NADH
Biochemistry, 41, 2002
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1L7D
 | | Crystal Structure of R. rubrum Transhydrogenase Domain I without Bound NAD(H) | | 分子名称: | nicotinamide nucleotide Transhydrogenase, subunit alpha 1 | | 著者 | Prasad, G.S, Wahlberg, M, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | | 登録日 | 2002-03-14 | | 公開日 | 2002-11-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal Structures of Transhydrogenase Domain I
with and without Bound NADH
Biochemistry, 41, 2002
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1PKG
 | | Structure of a c-Kit Kinase Product Complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, c-kit protein | | 著者 | Mol, C.D, Lim, K.B, Sridhar, V, Zou, H, Chien, E.Y.T, Sang, B.-C, Nowakowski, J, Kassel, D.B, Cronin, C.N, McRee, D.E. | | 登録日 | 2003-06-05 | | 公開日 | 2003-08-12 | | 最終更新日 | 2017-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of a c-Kit Product Complex Reveals the Basis for Kinase Transactivation.
J.Biol.Chem., 278, 2003
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1GAO
 | | CRYSTAL STRUCTURE OF THE L44S MUTANT OF FERREDOXIN I | | 分子名称: | FE3-S4 CLUSTER, FERREDOXIN I, IRON/SULFUR CLUSTER | | 著者 | Stout, C.D, Burgess, B.K, Prasad, G.S, Sridhar, V, Jung, Y.S. | | 登録日 | 2000-11-30 | | 公開日 | 2000-12-13 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Azotobacter vinelandii ferredoxin I: a sequence and structure comparison approach to alteration of [4Fe-4S]2+/+ reduction potential.
J.Biol.Chem., 277, 2002
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1A6L
 | | T14C MUTANT OF AZOTOBACTER VINELANDII FDI | | 分子名称: | FE3-S4 CLUSTER, FERREDOXIN, IRON/SULFUR CLUSTER | | 著者 | Gao-Sheridan, H.S, Kemper, M.A, Khayat, R, Armstrong, F.A, Prasad, G.S, Sridhar, V, Stout, C.D, Burgess, B.K. | | 登録日 | 1998-02-26 | | 公開日 | 1998-05-27 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A T14C variant of Azotobacter vinelandii ferredoxin I undergoes facile [3Fe-4S]0 to [4Fe-4S]2+ conversion in vitro but not in vivo.
J.Biol.Chem., 273, 1998
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1D4O
 | | CRYSTAL STRUCTURE OF TRANSHYDROGENASE DOMAIN III AT 1.2 ANGSTROMS RESOLUTION | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP(H) TRANSHYDROGENASE | | 著者 | Prasad, G.S, Sridhar, V, Yamaguchi, M, Hatefi, Y, Stout, C.D. | | 登録日 | 1999-10-04 | | 公開日 | 2000-01-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Crystal structure of transhydrogenase domain III at 1.2 A resolution.
Nat.Struct.Biol., 6, 1999
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2NWI
 | | Crystal structure of protein AF1396 from Archaeoglobus fulgidus, Pfam DUF98 | | 分子名称: | Hypothetical protein | | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Adams, J, Sridhar, V, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-11-14 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of hypothetical protein O28875 from Archaeoglobus fulgidus
To be Published
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2O3A
 | | Crystal structure of a protein AF_0751 from Archaeoglobus fulgidus | | 分子名称: | UPF0106 protein AF_0751 | | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Wu, B, Slocombe, A, Sridhar, V, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2006-12-01 | | 公開日 | 2006-12-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a protein AF_0751 from Archaeoglobus fulgidus
To be Published
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2OO6
 | | Crystal structure of putative L-alanine-DL-glutamate epimerase from Burkholderia xenovorans strain LB400 | | 分子名称: | Putative L-alanine-DL-glutamate epimerase, SULFATE ION | | 著者 | Bonanno, J.B, Dickey, M, Bain, K.T, Wu, B, Sridhar, V, Freeman, J, Smyth, L, Atwell, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-01-25 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of putative L-alanine-DL-glutamate epimerase from Burkholderia xenovorans strain LB400
To be Published
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4RQR
 | | Crystal Structure of Human Glutaredoxin with MESNA | | 分子名称: | 1-THIOETHANESULFONIC ACID, Glutaredoxin-1 | | 著者 | Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L. | | 登録日 | 2014-11-04 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
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4TT7
 | | Crystal structure of human ALK with a covalent modification | | 分子名称: | 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, ALK tyrosine kinase receptor | | 著者 | Badger, J, Sridhar, V, Chie-Leon, B, Nienaber, V.L, Hausheer, F.H. | | 登録日 | 2014-06-19 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787.
Onco Targets Ther, 8, 2015
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