1BUP
 
 | | T13S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Sousa, M.C, Mckay, D.B. | | 登録日 | 1998-09-03 | | 公開日 | 1998-09-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
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1KYI
 | | HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex | | 分子名称: | 4-IODO-3-NITROPHENYL ACETYL-LEUCINYL-LEUCINYL-LEUCINYL-VINYLSULFONE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ... | | 著者 | Sousa, M.C, Kessler, B.M, Overkleeft, H.S, McKay, D.B. | | 登録日 | 2002-02-04 | | 公開日 | 2002-05-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structure of HslUV Complexed with a Vinyl Sulfone Inhibitor:
Corroboration of a Proposed Mechanism of Allosteric Activation of
HslV by HslU
J.Mol.Biol., 318, 2002
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2BUP
 | | T13G Mutant of the ATPASE fragment of Bovine HSC70 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Sousa, M.C, Mckay, D.B. | | 登録日 | 1998-09-08 | | 公開日 | 1998-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
Biochemistry, 37, 1998
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1G3I
 | | CRYSTAL STRUCTURE OF THE HSLUV PROTEASE-CHAPERONE COMPLEX | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-DEPENDENT HSLU PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV | | 著者 | Sousa, M.C, Trame, C.B, Tsuruta, H, Wilbanks, S.M, Reddy, V.S, McKay, D.B. | | 登録日 | 2000-10-24 | | 公開日 | 2000-11-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Crystal and solution structures of an HslUV protease-chaperone complex.
Cell(Cambridge,Mass.), 103, 2000
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1G3K
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1JJW
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1JMV
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8GJH
 | | Salmonella ArnA | | 分子名称: | Bifunctional polymyxin resistance protein ArnA, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | | 著者 | Sousa, M.C, Mitchell, M.E, Gatzeva-Topalova, P.Z. | | 登録日 | 2023-03-15 | | 公開日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance.
Biochemistry, 62, 2023
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8T0J
 | | Salmonella Typhimurium ArnD | | 分子名称: | Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD | | 著者 | Sousa, M.C, Munoz-Escudero, D, Lee, M. | | 登録日 | 2023-06-01 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.
Biochemistry, 62, 2023
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4LDQ
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4LDR
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8FTN
 | | E. coli ArnA dehydrogenase domain mutant - N492A | | 分子名称: | Bifunctional UDP-4-amino-4-deoxy-L-arabinose formyltransferase/UDP-glucuronic acid oxidase ArnA, SULFATE ION | | 著者 | Sousa, M.C, Mitchell, M.E. | | 登録日 | 2023-01-12 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance.
Biochemistry, 62, 2023
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4OCA
 | | Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N | | 分子名称: | (2R,3R,4S,5S)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2H-pyr an-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase | | 著者 | Sousa, M.C, Lee, M. | | 登録日 | 2014-01-08 | | 公開日 | 2014-03-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria.
Biochemistry, 53, 2014
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4Q3J
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5CTA
 | | G158E/K44E/R57E/Y49E Bacillus subtilis lipase A with 10% [BMIM][Cl] | | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, Esterase | | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | | 登録日 | 2015-07-23 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure.
Chembiochem, 16, 2015
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1Z7E
 | | Crystal structure of full length ArnA | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID, protein ArnA | | 著者 | Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C. | | 登録日 | 2005-03-24 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005
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1Z73
 | | Crystal Structure of E. coli ArnA dehydrogenase (decarboxylase) domain, S433A mutant | | 分子名称: | GLYCEROL, SULFATE ION, protein ArnA | | 著者 | Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C. | | 登録日 | 2005-03-24 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005
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1YRW
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1Z75
 | | Crystal Structure of ArnA dehydrogenase (decarboxylase) domain, R619M mutant | | 分子名称: | GLYCEROL, SULFATE ION, protein ArnA | | 著者 | Gatzeva-Topalova, P.Z, May, A.P, Sousa, M.C. | | 登録日 | 2005-03-24 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure and Mechanism of ArnA: Conformational Change Implies Ordered Dehydrogenase Mechanism in Key Enzyme for Polymyxin Resistance
Structure, 13, 2005
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1Z74
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1Z7B
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5EFR
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3EFC
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4HDJ
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1U2M
 | | Crystal Structure of Skp | | 分子名称: | Histone-like protein HLP-1 | | 著者 | Walton, T.A, Sousa, M.C. | | 登録日 | 2004-07-19 | | 公開日 | 2004-08-24 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Skp, a Prefoldin-like Chaperone that Protects Soluble and Membrane Proteins from Aggregation
Mol.Cell, 15, 2004
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