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8CX9
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BU of 8cx9 by Molmil
Structure of the SARS-COV2 PLpro (C111S) in complex with a dimeric Ubv that inhibits activity by an unusual allosteric mechanism
Descriptor: BROMIDE ION, CHLORIDE ION, Papain-like protease nsp3, ...
Authors:Singer, A.U, Slater, C.L, Patel, A, Russel, R, Mark, B.L, Sidhu, S.S.
Deposit date:2022-05-20
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.
Plos Pathog., 18, 2022

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