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1UKY
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BU of 1uky by Molmil
SUBSTRATE SPECIFICITY AND ASSEMBLY OF CATALYTIC CENTER DERIVED FROM TWO STRUCTURES OF LIGATED URIDYLATE KINASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, URIDYLATE KINASE
Authors:Mueller-Dieckmann, H.-J, Schulz, G.E.
Deposit date:1994-07-13
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Substrate specificity and assembly of the catalytic center derived from two structures of ligated uridylate kinase.
J.Mol.Biol., 246, 1995
1VTK
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BU of 1vtk by Molmil
THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND DEOXYTHYMIDINE-MONOPHOSPHATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, THYMIDINE KINASE, THYMIDINE-5'-PHOSPHATE
Authors:Wild, K, Schulz, G.E.
Deposit date:1997-04-01
Release date:1997-10-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue.
Protein Sci., 6, 1997
2JCD
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BU of 2jcd by Molmil
Structure of the N-oxygenase AurF from Streptomyces thioluteus
Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, N-OXIDASE
Authors:Zocher, G.E, Winkler, R, Hertweck, C, Schulz, G.E.
Deposit date:2006-12-21
Release date:2007-09-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structure and Action of the N-Oxygenase Aurf from Streptomyces Thioluteus.
J.Mol.Biol., 373, 2007
1OJR
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BU of 1ojr by Molmil
L-rhamnulose-1-phosphate aldolase from Escherichia coli (mutant E192A)
Descriptor: 1,4-DIETHYLENE DIOXIDE, Dihydroxyacetone, GLYCEROL, ...
Authors:Kroemer, M, Merkel, I, Schulz, G.E.
Deposit date:2003-07-15
Release date:2003-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure and Catalytic Mechanism of L-Rhamnulose-1-Phosphate Aldolase.
Biochemistry, 42, 2003
1AKY
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BU of 1aky by Molmil
HIGH-RESOLUTION STRUCTURES OF ADENYLATE KINASE FROM YEAST LIGATED WITH INHIBITOR AP5A, SHOWING THE PATHWAY OF PHOSPHORYL TRANSFER
Descriptor: ADENYLATE KINASE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, IMIDAZOLE
Authors:Abele, U, Schulz, G.E.
Deposit date:1995-07-28
Release date:1995-11-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:High-resolution structures of adenylate kinase from yeast ligated with inhibitor Ap5A, showing the pathway of phosphoryl transfer.
Protein Sci., 4, 1995
1FUA
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BU of 1fua by Molmil
L-FUCULOSE 1-PHOSPHATE ALDOLASE CRYSTAL FORM T
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE-1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Dreyer, M.K, Schulz, G.E.
Deposit date:1996-02-14
Release date:1996-10-14
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Refined high-resolution structure of the metal-ion dependent L-fuculose-1-phosphate aldolase (class II) from Escherichia coli.
Acta Crystallogr.,Sect.D, 52, 1996
1H3A
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BU of 1h3a by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (2E)-N-ALLYL-4-{[3-(4-BROMOPHENYL)-5-FLUORO-1-METHYL-1H-INDAZOL-6-YL]OXY}-N-METHYL-2-BUTEN-1-AMINE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1H39
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Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6-YL]OXY}HEXYL)-N-METHYLAMINE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1H3B
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BU of 1h3b by Molmil
Squalene-Hopene Cyclase
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-{6-[4-(6-BROMO-1,2-BENZISOTHIAZOL-3-YL)PHENOXY]HEXYL}-N-METHYL-2-PROPEN-1-AMINE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-25
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1H35
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BU of 1h35 by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (4'-{[ALLYL(METHYL)AMINO]METHYL}-1,1'-BIPHENYL-4-YL)(4-BROMOPHENYL)METHANONE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1H37
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BU of 1h37 by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE, {4-[((1S,2S)-2-{[ALLYL(CYCLOPROPYL)AMINO]METHYL}CYCLOPROPYL)METHOXY]PHENYL}(4-BROMOPHENYL)METHANONE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1H3C
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BU of 1h3c by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-25
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1H36
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BU of 1h36 by Molmil
Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme
Descriptor: (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMINO]BUT-2-ENYL}OXY)PHENYL]METHANONE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE
Authors:Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E.
Deposit date:2002-08-24
Release date:2003-08-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase
J.Med.Chem., 46, 2003
1GSZ
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BU of 1gsz by Molmil
Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE, [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE
Authors:Lenhart, A, Weihofen, W.A, Pleschke, A.E.W, Schulz, G.E.
Deposit date:2002-01-09
Release date:2003-01-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Chem.Biol., 9, 2002
1CGT
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BU of 1cgt by Molmil
STRUCTURE OF CYCLODEXTRIN GLYCOSYLTRANSFERASE REFINED AT 2.0 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, CYCLODEXTRIN GLYCOSYL-TRANSFERASE
Authors:Klein, C, Schulz, G.E.
Deposit date:1992-06-10
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of cyclodextrin glycosyltransferase refined at 2.0 A resolution.
J.Mol.Biol., 217, 1991
1E4A
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BU of 1e4a by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant Del(27)
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E47
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BU of 1e47 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73Q
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of l-fuculose-1-phosphate aldolase mutants outlining motions during catalysis.
J. Mol. Biol., 303, 2000
1E4C
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BU of 1e4c by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant S71Q
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E49
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L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant N29L/S71A
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E46
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L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73S
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E4B
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L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant N29Q
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E48
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BU of 1e48 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73Q/Y113F/Y209F
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
2BHS
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BU of 2bhs by Molmil
Crystal Structure of Cysteine Synthase B
Descriptor: CYSTEINE SYNTHASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Claus, M.T, Zocher, G.E, Maier, T.H.P, Schulz, G.E.
Deposit date:2005-01-18
Release date:2005-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structure of the O-Acetylserine Sulfhydrylase Isoenzyme Cysm from Escherichia Coli
Biochemistry, 44, 2005
2BHT
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BU of 2bht by Molmil
Crystal structure of O-acetylserine sulfhydrylase B
Descriptor: CYSTEINE SYNTHASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Claus, M.T, Zocher, G.E, Maier, T.H.P, Schulz, G.E.
Deposit date:2005-01-18
Release date:2005-06-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the O-Acetylserine Sulfhydrylase Isoenzyme Cysm from Escherichia Coli
Biochemistry, 44, 2005
2V2B
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L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT E117S- E192A-K248G-R253A-E254A)
Descriptor: ACETATE ION, PHOSPHATE ION, R-1,2-PROPANEDIOL, ...
Authors:Grueninger, D, Schulz, G.E.
Deposit date:2007-06-04
Release date:2008-01-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Antenna Domain Mobility and Enzymatic Reaction of L-Rhamnulose-1-Phosphate Aldolase.
Biochemistry, 47, 2008

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