1DB5
| HUMAN S-PLA2 IN COMPLEX WITH INDOLE 6 | Descriptor: | 4-(1-BENZYL-3-CARBAMOYLMETHYL-2-METHYL-1H-INDOL-5-YLOXY)-BUTYRIC ACID, CALCIUM ION, PROTEIN (PHOSPHOLIPASE A2) | Authors: | Chirgadze, N.Y, Schevitz, R.W, Wery, J.-P. | Deposit date: | 1999-11-02 | Release date: | 1999-11-12 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2. Nat.Struct.Biol., 2, 1995
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1DB4
| HUMAN S-PLA2 IN COMPLEX WITH INDOLE 8 | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2, [3-(1-BENZYL-3-CARBAMOYLMETHYL-2-METHYL-1H-INDOL-5-YLOXY)-PROPYL-]-PHOSPHONIC ACID | Authors: | Chirgadze, N.Y, Schevitz, R.W, Wery, J.-P. | Deposit date: | 1999-11-02 | Release date: | 1999-11-12 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2. Nat.Struct.Biol., 2, 1995
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1DCY
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1TRO
| CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION | Descriptor: | DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN | Authors: | Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B. | Deposit date: | 1992-08-30 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of trp repressor/operator complex at atomic resolution. Nature, 335, 1988
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1AX8
| Human obesity protein, leptin | Descriptor: | OBESITY PROTEIN | Authors: | Zhang, F, Beals, J.M, Briggs, S.L, Clawson, D.K, Wery, J.-P, Schevitz, R.W. | Deposit date: | 1997-10-31 | Release date: | 1998-11-25 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the obese protein leptin-E100. Nature, 387, 1997
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1BBC
| STRUCTURE OF RECOMBINANT HUMAN RHEUMATOID ARTHRITIC SYNOVIAL FLUID PHOSPHOLIPASE A2 AT 2.2 ANGSTROMS RESOLUTION | Descriptor: | PHOSPHOLIPASE A2 | Authors: | Wery, J.-P, Schevitz, R.W, Clawson, D.K, Bobbitt, J.L, Dow, E.R, Gamboa, G, Goodsonjunior, T, Hermann, R.B, Kramer, R.M, Mcclure, D.B, Mihelich, E.D, Putnam, J.E, Sharp, J.D, Stark, D.H, Teater, C, Warrick, M.W, Jones, N.D. | Deposit date: | 1992-05-04 | Release date: | 1993-10-31 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 A resolution. Nature, 352, 1991
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1ET1
| CRYSTAL STRUCTURE OF HUMAN PARATHYROID HORMONE 1-34 AT 0.9 A RESOLUTION | Descriptor: | PARATHYROID HORMONE, SODIUM ION | Authors: | Jin, L, Briggs, S.L, Chandrasekhar, S, Chirgadze, N.Y, Clawson, D.K, Schevitz, R.W, Smiley, D.L, Tashjian, A.H, Zhang, F. | Deposit date: | 2000-04-12 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution. J.Biol.Chem., 275, 2000
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3WRP
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1WRP
| FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR | Descriptor: | TRP REPRESSOR, TRYPTOPHAN | Authors: | Schewitz, R.W, Otwinowski, Z, Lawson, C.L, Joachimiak, A, Sigler, P.B. | Deposit date: | 1987-12-01 | Release date: | 1988-04-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Flexibility of the DNA-binding domains of trp repressor. Proteins, 3, 1988
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2OZ9
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8LDH
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3LDH
| A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes | Descriptor: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID | Authors: | White, J.L, Hackert, M.L, Buehner, M, Adams, M.J, Ford, G.C, Lentzjunior, P.J, Smiley, I.E, Steindel, S.J, Rossmann, M.G. | Deposit date: | 1974-06-06 | Release date: | 1977-04-29 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes. J.Mol.Biol., 102, 1976
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6LDH
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1LDM
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1YFG
| YEAST INITIATOR TRNA | Descriptor: | YEAST INITIATOR TRNA | Authors: | Basavappa, R, Sigler, P.B. | Deposit date: | 1997-05-08 | Release date: | 1997-09-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination. EMBO J., 10, 1991
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1D3Q
| CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH BENZO[B]THIOPHENE INHIBITOR 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[4-(2-PYRROLIDIN-1-YL-ETHOXY)-BENZYL]-2-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYL] -BENZO[B]THIOPHENE, ALPHA-THROMBIN, ... | Authors: | Chirgadze, N.Y. | Deposit date: | 1999-09-30 | Release date: | 2000-10-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors. Protein Sci., 9, 2000
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1D3D
| CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH BENZOTHIOPHENE INHIBITOR 4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-BROMO-4-PYRROLIDIN-1-YLMETHYL-BENZYL)-2-[4-PYRROLIDIN-1-YL-ETHOXY)-PHENYL]-BENZO[B]THIOPHEN-6-OL, ALPHA-THROMBIN, ... | Authors: | Chirgadze, N.Y. | Deposit date: | 1999-09-29 | Release date: | 2000-10-04 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors Protein Sci., 9, 2000
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1D3P
| CRYSTAL STRUCTURE OF HUMAN APLHA-THROMBIN IN COMPLEX WITH BENZO[B]THIOPHENE INHIBITOR 3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[4-(2-PYRROLIDIN-1-YL-ETHOXY)-BENZYL]-2-4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYL] -BENZO[B]THIOPHEN-6-OL, ALPHA-THROMBIN, ... | Authors: | Chirgadze, N.Y. | Deposit date: | 1999-09-30 | Release date: | 2000-10-04 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors. Protein Sci., 9, 2000
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1D3T
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1ZT9
| E. coli trp repressor, tetragonal crystal form | Descriptor: | SULFATE ION, TRYPTOPHAN, Trp operon repressor | Authors: | Lawson, C.L, Chin, A.S, Benoff, B, Yung, B.H. | Deposit date: | 2005-05-26 | Release date: | 2006-05-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two association modes for E. coli trp repressor dimer-dimer interactions To be Published
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