5B74
| Crystal structure of conjoined Pyrococcus furiosus L-asparaginase with peptide | Descriptor: | CHLORIDE ION, CITRATE ANION, L-asparaginase, ... | Authors: | Sharma, P, Tomar, R, Nath, S.K, Kundu, B, Ashish, F. | Deposit date: | 2016-06-05 | Release date: | 2017-06-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.039 Å) | Cite: | Heat induces end to end repetitive association in P. furiosus L-asparaginase which enables its thermophilic property. Sci Rep, 10, 2020
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5BST
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5BSU
| Crystal structure of 4-coumarate:CoA ligase complexed with caffeoyl adenylate | Descriptor: | 4-coumarate--CoA ligase 2, 5'-O-[(R)-{[(2E)-3-(3,4-dioxocyclohexa-1,5-dien-1-yl)prop-2-enoyl]oxy}(hydroxy)phosphoryl]adenosine, GLYCEROL, ... | Authors: | Li, Z, Nair, S.K. | Deposit date: | 2015-06-02 | Release date: | 2016-05-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Specificity and Flexibility in a Plant 4-Coumarate:CoA Ligase. Structure, 23, 2015
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5SV0
| Structure of the ExbB/ExbD complex from E. coli at pH 7.0 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Biopolymer transport protein ExbB, CALCIUM ION | Authors: | Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N. | Deposit date: | 2016-08-04 | Release date: | 2016-09-28 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insight into the role of the Ton complex in energy transduction. Nature, 538, 2016
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5SV1
| Structure of the ExbB/ExbD complex from E. coli at pH 4.5 | Descriptor: | Biopolymer transport protein ExbB, Biopolymer transport protein ExbD, MERCURY (II) ION | Authors: | Celia, H, Botos, I, Lloubes, R, Buchanan, S.K, Noinaj, N. | Deposit date: | 2016-08-04 | Release date: | 2016-09-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural insight into the role of the Ton complex in energy transduction. Nature, 538, 2016
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5T12
| N-terminal domain of Enzyme 1 - Nitrogen | Descriptor: | IODIDE ION, Phosphoenolpyruvate--protein phosphotransferase | Authors: | Stanley, A.M, Botos, I, Buchanan, S.K. | Deposit date: | 2016-08-17 | Release date: | 2016-11-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Structure of the NPr:EIN(Ntr) Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems. Structure, 24, 2016
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5U55
| Psf4 in complex with Mn2+ and (S)-2-HPP | Descriptor: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, (S)-2-hydroxypropylphosphonic acid epoxidase, MANGANESE (II) ION | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2016-12-06 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. ACS Chem. Biol., 12, 2017
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5U5D
| Psf4 in complex with Mn2+ and (R)-2-HPP | Descriptor: | (S)-2-hydroxypropylphosphonic acid epoxidase, MANGANESE (II) ION, [(2R)-2-hydroxypropyl]phosphonic acid | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2016-12-06 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. ACS Chem. Biol., 12, 2017
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5TV8
| A. aeolicus BioW with AMP-CPP and pimelate | Descriptor: | 6-carboxyhexanoate--CoA ligase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... | Authors: | Estrada, P, Manandhar, M, Dong, S.-H, Deveryshetty, J, Agarwal, V, Cronan, J.E, Nair, S.K. | Deposit date: | 2016-11-08 | Release date: | 2016-12-07 | Last modified: | 2017-05-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes. Nat. Chem. Biol., 13, 2017
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5TVA
| A. aeolicus BioW with AMP and CoA | Descriptor: | 6-carboxyhexanoate--CoA ligase, ADENOSINE MONOPHOSPHATE, COENZYME A | Authors: | Estrada, P, Manandhar, M, Dong, S.-H, Deveryshetty, J, Agarwal, V, Cronan, J.E, Nair, S.K. | Deposit date: | 2016-11-08 | Release date: | 2016-12-07 | Last modified: | 2017-05-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes. Nat. Chem. Biol., 13, 2017
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5TTY
| PagF prenyltransferase | Descriptor: | DI(HYDROXYETHYL)ETHER, PagF prenyltransferase | Authors: | Hao, Y, Nair, S.K. | Deposit date: | 2016-11-04 | Release date: | 2016-11-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5TV6
| A. aeolicus BioW with pimelate | Descriptor: | 6-carboxyhexanoate--CoA ligase, PIMELIC ACID | Authors: | Estrada, P, Manandhar, M, Dong, S.-H, Deveryshetty, J, Agarwal, V, Cronan, J.E, Nair, S.K. | Deposit date: | 2016-11-08 | Release date: | 2016-12-07 | Last modified: | 2017-05-31 | Method: | X-RAY DIFFRACTION (2.456 Å) | Cite: | The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes. Nat. Chem. Biol., 13, 2017
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5TX2
| Miniature TGF-beta2 3-mutant monomer | Descriptor: | Transforming growth factor beta-2 | Authors: | Taylor, A.B, Kim, S.K, Hart, P.J, Hinck, A.P. | Deposit date: | 2016-11-15 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling. J. Biol. Chem., 292, 2017
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5TU5
| PagF prenyltransferase with Tyr-Tyr-Tyr and DMSPP | Descriptor: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, PagF prenyltransferase, ... | Authors: | Hao, Y, Nair, S.K. | Deposit date: | 2016-11-04 | Release date: | 2016-11-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5TXE
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5DA3
| Crystal structure of PTK6 Kinase domain with inhibitor | Descriptor: | (2-chloro-4-{[6-cyclopropyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}phenyl)(morpholin-4-yl)methanone, GLYCEROL, Protein-tyrosine kinase 6 | Authors: | Thakur, M.K, Birudukota, S, Swaminathan, S, Battula, S.K, Vadivelu, S, Tyagi, R, Gosu, R. | Deposit date: | 2015-08-19 | Release date: | 2016-08-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Co-crystal structures of PTK6: With Dasatinib at 2.24 angstrom , with novel imidazo[1,2-a]pyrazin-8-amine derivative inhibitor at 1.70 angstrom resolution Biochem. Biophys. Res. Commun., 482, 2017
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5U5G
| Psf3 in complex with NADP+ and 2-OPP | Descriptor: | (2-oxopropyl)phosphonic acid, 6-phosphogluconate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Olivares, P, Nair, S.K. | Deposit date: | 2016-12-06 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.048 Å) | Cite: | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. ACS Chem. Biol., 12, 2017
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2F6L
| X-ray structure of Chorismate Mutase from Mycobacterium Tuberculosis | Descriptor: | Chorismate mutase | Authors: | Kim, S.K, Howard, A.J, Gilliland, G.L, Reddy, P.T, Ladner, J.E. | Deposit date: | 2005-11-29 | Release date: | 2005-12-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids. J.Bacteriol., 188, 2006
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5TXC
| AtxE2 Isopeptidase - APO | Descriptor: | AtxE2 | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2016-11-16 | Release date: | 2016-12-21 | Last modified: | 2017-01-04 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates. J. Am. Chem. Soc., 138, 2016
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5UAO
| Crystal structure of MibH, a lathipeptide tryptophan 5-halogenase | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Tryptophane-5-halogenase | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2016-12-19 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis. ACS Chem. Biol., 12, 2017
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5TTE
| Crystal Structure of an RBR E3 ubiquitin ligase in complex with an E2-Ub thioester intermediate mimic | Descriptor: | E3 ubiquitin-protein ligase ARIH1, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... | Authors: | Yuan, L, Lv, Z, Olsen, S.K. | Deposit date: | 2016-11-03 | Release date: | 2017-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI. Nat Commun, 8, 2017
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5U58
| Psf4 in complex with Fe2+ and (R)-2-HPP | Descriptor: | (S)-2-hydroxypropylphosphonic acid epoxidase, FE (III) ION, [(2R)-2-hydroxypropyl]phosphonic acid | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2016-12-06 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads. ACS Chem. Biol., 12, 2017
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5TU6
| PagF prenyltransferase with cyclic[INPYLYP] and DMSPP | Descriptor: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, METHIONINE, ... | Authors: | Hao, Y, Nair, S.K. | Deposit date: | 2016-11-04 | Release date: | 2016-11-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5TU4
| PagF with Boc-Tyr and DMSPP | Descriptor: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, N-(tert-butoxycarbonyl)-L-tyrosine, ... | Authors: | Hao, Y, Nair, S.K. | Deposit date: | 2016-11-04 | Release date: | 2016-11-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5TV5
| BioW from Aquifex aeoulicus | Descriptor: | 6-carboxyhexanoate--CoA ligase | Authors: | Estrada, P, Manandhar, M, Dong, S.-H, Deveryshetty, J, Agarwal, V, Cronan, J.E, Nair, S.K. | Deposit date: | 2016-11-08 | Release date: | 2016-12-07 | Last modified: | 2017-05-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes. Nat. Chem. Biol., 13, 2017
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