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6D1U
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Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer in complex with adrenomedullin 2/intermedin
Descriptor: ADM2, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, SODIUM ION, ...
Authors:Pioszak, A, Roehrkasse, A.
Deposit date:2018-04-12
Release date:2018-09-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-function analyses reveal a triple beta-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design.
J. Biol. Chem., 293, 2018

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