6SUE
 
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6YEY
 | | Xenorhabdus nematophila XptA1 in complex with porcine mucosa heparin | | Descriptor: | A component of insecticidal toxin complex (Tc) | | Authors: | Roderer, D, Broecker, F, Sitsel, O, Kaplonek, P, Leidreiter, F, Seeberger, P.H, Raunser, S. | | Deposit date: | 2020-03-25 | | Release date: | 2020-07-08 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Glycan-dependent cell adhesion mechanism of Tc toxins.
Nat Commun, 11, 2020
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6YEW
 | | Morganella morganii TcdA4 in complex with porcine mucosa heparin | | Descriptor: | Insecticidal toxin protein | | Authors: | Roderer, D, Broecker, F, Sitsel, O, Kaplonek, P, Leidreiter, F, Seeberger, P.H, Raunser, S. | | Deposit date: | 2020-03-25 | | Release date: | 2020-07-08 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Glycan-dependent cell adhesion mechanism of Tc toxins.
Nat Commun, 11, 2020
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6SUQ
 | | Crystal Structure of TcdB2-TccC3-TEV | | Descriptor: | TcdB2,TccC3,Genome polyprotein | | Authors: | Roderer, D, Schubert, E, Sitsel, O, Raunser, S. | | Deposit date: | 2019-09-16 | | Release date: | 2019-12-04 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Towards the application of Tc toxins as a universal protein translocation system.
Nat Commun, 10, 2019
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6SUF
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6SUP
 | | Crystal Structure of TcdB2-TccC3-Cdc42 | | Descriptor: | MAGNESIUM ION, TcdB2,TccC3,Cell division control protein 42 homolog | | Authors: | Roderer, D, Schubert, E, Sitsel, O, Raunser, S. | | Deposit date: | 2019-09-16 | | Release date: | 2019-12-04 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Towards the application of Tc toxins as a universal protein translocation system.
Nat Commun, 10, 2019
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8OXZ
 | | Rat alpha5beta1 integrin, headpiece | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-1, Integrin subunit alpha 5 | | Authors: | Roderer, D, Dransart, E, Shafaq-Zadah, M, Bartels, R, Johannes, L. | | Deposit date: | 2023-05-03 | | Release date: | 2024-11-13 | | Last modified: | 2025-11-26 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Spatial N-glycan rearrangement on alpha 5 beta 1 integrin nucleates galectin-3 oligomers to determine endocytic fate.
Nat Commun, 16, 2025
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6RW8
 | | Cryo-EM structure of Xenorhabdus nematophila XptA1 | | Descriptor: | A component of insecticidal toxin complex (Tc) | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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6RW9
 | | Cryo-EM structure of Morganella morganii TcdA4 | | Descriptor: | Insecticidal toxin protein TcdA4 | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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6RWB
 | | Cryo-EM structure of Yersinia pseudotuberculosis TcaA-TcaB | | Descriptor: | Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit,Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit,Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit,Toxin,Toxin complex subunit TcaB,Putative toxin subunit,Putative toxin subunit | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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6RWA
 | | Cryo-EM structure of Photorhabdus luminescens TcdA4 | | Descriptor: | TcdA4 | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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6RW6
 | | Cryo-EM structure of Photorhabdus luminescens TcdA1 | | Descriptor: | TcdA1 | | Authors: | Roderer, D, Leidreiter, F, Gatsogiannis, C, Meusch, D, Benz, R, Raunser, S. | | Deposit date: | 2019-06-04 | | Release date: | 2019-10-23 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Common architecture of Tc toxins from human and insect pathogenic bacteria.
Sci Adv, 5, 2019
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9GH4
 | | Fusobacterium nucleatum adhesin CbpF | | Descriptor: | Cell surface protein | | Authors: | Roderer, D, Marongiu, G.L, Fink, U. | | Deposit date: | 2024-08-15 | | Release date: | 2025-04-02 | | Last modified: | 2025-04-23 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis for immune cell binding of Fusobacterium nucleatum via the trimeric autotransporter adhesin CbpF.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9GD8
 | | NME1 94-Diphosphoserine | | Descriptor: | Nucleoside diphosphate kinase A | | Authors: | Roderer, D, Schoepf, F, Fiedler, D, Celik, A. | | Deposit date: | 2024-08-05 | | Release date: | 2025-06-11 | | Last modified: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation.
Nat.Chem., 17, 2025
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9GD6
 | | NME1 94-Phosphoserine | | Descriptor: | Nucleoside diphosphate kinase A | | Authors: | Roderer, D, Schoepf, F, Fiedler, D, Celik, A. | | Deposit date: | 2024-08-05 | | Release date: | 2025-06-11 | | Last modified: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation.
Nat.Chem., 17, 2025
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9GD9
 | | NME1 94-Oligophosphoserine | | Descriptor: | Nucleoside diphosphate kinase A | | Authors: | Roderer, D, Schoepf, F, Fiedler, D, Celik, A. | | Deposit date: | 2024-08-05 | | Release date: | 2025-06-11 | | Last modified: | 2025-11-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation.
Nat.Chem., 17, 2025
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9QE7
 | | Membrane-distal part of extracellular domain of the Fap2 autotransporter adhesin from Fusobacterium nucleatum ATCC23726 | | Descriptor: | Outer membrane autotransporter barrel domain protein | | Authors: | Schoepf, F, Marongiu, G.L, Milaj, K, Sprink, T, Kikhney, J, Moter, A, Roderer, D. | | Deposit date: | 2025-03-07 | | Release date: | 2025-07-30 | | Last modified: | 2025-09-10 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells.
Nat Commun, 16, 2025
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8CQ2
 | | Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, C16S, C20S, C870S, T1279C mutant | | Descriptor: | TcdA1 | | Authors: | Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S. | | Deposit date: | 2023-03-03 | | Release date: | 2024-03-13 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Multistate kinetics of the syringe-like injection mechanism of Tc toxins.
Sci Adv, 11, 2025
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8CPZ
 | | Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K1179W mutant | | Descriptor: | TcdA1 | | Authors: | Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S. | | Deposit date: | 2023-03-03 | | Release date: | 2024-03-13 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Multistate kinetics of the syringe-like injection mechanism of Tc toxins.
Sci Adv, 11, 2025
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8CQ0
 | | Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K567W K2008W mutant | | Descriptor: | TcdA1 | | Authors: | Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S. | | Deposit date: | 2023-03-03 | | Release date: | 2024-03-13 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Multistate kinetics of the syringe-like injection mechanism of Tc toxins.
Sci Adv, 11, 2025
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5LKI
 | | Cryo-EM structure of the Tc toxin TcdA1 in its pore state | | Descriptor: | TcdA1 | | Authors: | Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S. | | Deposit date: | 2016-07-22 | | Release date: | 2016-08-31 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Membrane insertion of a Tc toxin in near-atomic detail.
Nat.Struct.Mol.Biol., 23, 2016
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5LKH
 | | Cryo-EM structure of the Tc toxin TcdA1 in its pore state (obtained by flexible fitting) | | Descriptor: | TcdA1 | | Authors: | Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S. | | Deposit date: | 2016-07-22 | | Release date: | 2016-08-31 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Membrane insertion of a Tc toxin in near-atomic detail.
Nat.Struct.Mol.Biol., 23, 2016
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6H6E
 | | PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3) | | Descriptor: | TcdA1, TcdB2,TccC3 | | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | | Deposit date: | 2018-07-27 | | Release date: | 2018-10-03 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.95 Å) | | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller.
Nature, 563, 2018
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6H6F
 | | PTC3 holotoxin complex from Photorhabdus luminiscens - Mutant TcC-D651A | | Descriptor: | TcdA1, TcdB2,TccC3,TccC3 | | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | | Deposit date: | 2018-07-27 | | Release date: | 2018-10-03 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.72 Å) | | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller.
Nature, 563, 2018
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6H6G
 | | Crystal Structure of TcdB2-TccC3 without hypervariable C-terminal region | | Descriptor: | TcdB2,TccC3 | | Authors: | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | | Deposit date: | 2018-07-27 | | Release date: | 2018-10-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.004 Å) | | Cite: | Tc toxin activation requires unfolding and refolding of a beta-propeller.
Nature, 563, 2018
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