8D18
 
 | | Straight ADP-F-actin 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-05-26 | | Release date: | 2022-09-07 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D14
 | | Helical ADP-Pi-F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-05-26 | | Release date: | 2022-09-07 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D15
 | | Bent ADP-F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-05-26 | | Release date: | 2022-09-07 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D17
 | | Straight ADP-F-actin 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-05-26 | | Release date: | 2022-09-07 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.69 Å) | | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D13
 | | Helical ADP-F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-05-26 | | Release date: | 2022-09-07 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.43 Å) | | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D16
 | | Bent ADP-Pi-F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-05-26 | | Release date: | 2022-09-07 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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9DIL
 | | Cryo-EM structure of VCP/p97 in complex with VCPIP1 (VCIP135) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Deubiquitinating protein VCPIP1, Transitional endoplasmic reticulum ATPase | | Authors: | Vostal, L.E, Reynolds, M.J, Kapoor, T.M. | | Deposit date: | 2024-09-05 | | Release date: | 2025-03-26 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into the coupling between VCP, an essential unfoldase, and a deubiquitinase.
J.Cell Biol., 224, 2025
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8VO5
 | | Cryo-EM structure of fascin bound to F-actin (actin binding site 1) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2024-01-14 | | Release date: | 2025-01-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Fascin structural plasticity mediates flexible actin bundle construction.
Nat.Struct.Mol.Biol., 32, 2025
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8VO7
 | | Cryo-EM structure of fascin crosslinked F-actin | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2024-01-14 | | Release date: | 2025-01-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Fascin structural plasticity mediates flexible actin bundle construction.
Nat.Struct.Mol.Biol., 32, 2025
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8VO8
 | | Cryo-EM structure of fascin crosslinked F-actin (Eigen_left) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2024-01-14 | | Release date: | 2025-01-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Fascin structural plasticity mediates flexible actin bundle construction.
Nat.Struct.Mol.Biol., 32, 2025
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8VO6
 | | Cryo-EM structure of fascin bound to F-actin (actin binding site 2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2024-01-14 | | Release date: | 2025-01-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Fascin structural plasticity mediates flexible actin bundle construction.
Nat.Struct.Mol.Biol., 32, 2025
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8VOA
 | | Cryo-EM structure of fascin crosslinked F-actin (Eigen_right) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2024-01-14 | | Release date: | 2025-01-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Fascin structural plasticity mediates flexible actin bundle construction.
Nat.Struct.Mol.Biol., 32, 2025
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8VO9
 | | Cryo-EM structure of fascin crosslinked F-actin (Eigen_middle) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2024-01-14 | | Release date: | 2025-01-15 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Fascin structural plasticity mediates flexible actin bundle construction.
Nat.Struct.Mol.Biol., 32, 2025
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9DVA
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7R8V
 | | Cryo-EM structure of the ADP state actin filament | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Espinosa de los Reyes, S, Reynolds, M.J, Gurel, P, Alushin, G.M. | | Deposit date: | 2021-06-27 | | Release date: | 2021-07-28 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7RB9
 | | Cryo-EM structure of the rigor state Jordan myosin-15-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M. | | Deposit date: | 2021-07-05 | | Release date: | 2021-07-28 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.76 Å) | | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7RB8
 | | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M. | | Deposit date: | 2021-07-05 | | Release date: | 2021-07-28 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.63 Å) | | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7R91
 | | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M. | | Deposit date: | 2021-06-28 | | Release date: | 2021-07-28 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7SX8
 | | T-Plastin-F-actin complex, parallel bundled state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Mei, L, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2021-11-22 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7SX9
 | | T-Plastin-F-actin complex, anti-parallel bundled state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Mei, L, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2021-11-22 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (10 Å) | | Cite: | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7SXA
 | | T-Plastin-F-actin complex, pre-bundling intermediate state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Mei, L, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2021-11-22 | | Release date: | 2022-08-31 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (6.87 Å) | | Cite: | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7UDT
 | | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-03-20 | | Release date: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7UDU
 | | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Gong, R, Reynolds, M.J, Alushin, G.M. | | Deposit date: | 2022-03-20 | | Release date: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (4.15 Å) | | Cite: | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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6UPV
 | | Alpha-E-catenin ABD-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Mei, L, Alushin, G.M. | | Deposit date: | 2019-10-18 | | Release date: | 2020-09-30 | | Last modified: | 2025-04-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
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6UPW
 | | Metavinculin ABD-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Mei, L, Alushin, G.M. | | Deposit date: | 2019-10-18 | | Release date: | 2020-09-30 | | Last modified: | 2025-04-02 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
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