5JV3
| The neck-linker and alpha 7 helix of Homo sapiens Eg5 fused to EB1 | Descriptor: | CALCIUM ION, Chimera protein of Kinesin-like protein KIF11 and Microtubule-associated protein RP/EB family member 1 | Authors: | Phillips, R.K, Rayment, I. | Deposit date: | 2016-05-10 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.006 Å) | Cite: | Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
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5JVS
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5JVU
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5JVM
| The neck-linker and alpha 7 helix of Mus musculus KIF3C | Descriptor: | Chimera protein of Kinesin-like protein KIF3C and Microtubule-associated protein RP/EB family member 1, MAGNESIUM ION | Authors: | Phillips, R.K, Rayment, I. | Deposit date: | 2016-05-11 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.567 Å) | Cite: | Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
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5JVR
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3GAH
| Structure of a F112H variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, COBALAMIN, Cobalamin adenosyltransferase PduO-like protein, ... | Authors: | St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | Deposit date: | 2009-02-17 | Release date: | 2009-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry, 48, 2009
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3GAJ
| Structure of a C-terminal deletion variant of a PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, COBALAMIN, Cobalamin adenosyltransferase PduO-like protein, ... | Authors: | St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | Deposit date: | 2009-02-17 | Release date: | 2009-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry, 48, 2009
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3GAI
| Structure of a F112A variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, COBALAMIN, ... | Authors: | St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. | Deposit date: | 2009-02-17 | Release date: | 2009-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry, 48, 2009
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3KAR
| THE MOTOR DOMAIN OF KINESIN-LIKE PROTEIN KAR3, A SACCHAROMYCES CEREVISIAE KINESIN-RELATED PROTEIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KAR3, MAGNESIUM ION | Authors: | Gulick, A.M, Song, H, Endow, S, Rayment, I. | Deposit date: | 1997-11-26 | Release date: | 1998-04-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution. Biochemistry, 37, 1998
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5CHX
| Crystal Structure of amino acids 1590-1657 of MYH7 | Descriptor: | Xrcc4-MYH7-1590-1657 | Authors: | Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinz, N.T, Cui, Q, Rayment, I. | Deposit date: | 2015-07-10 | Release date: | 2015-12-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A composite approach towards a complete model of the myosin rod. Proteins, 84, 2016
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5CJ0
| Crystal Structure of Amino Acids 1631-1692 of MYH7 | Descriptor: | Xrcc4-MYH7-(1631-1692) chimera protein | Authors: | Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I. | Deposit date: | 2015-07-13 | Release date: | 2015-12-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A composite approach towards a complete model of the myosin rod. Proteins, 84, 2016
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5CJ1
| Crystal structure of the coiled coil of MYH7 residues 1526 to 1571 fused to Gp7 | Descriptor: | Gp7-MYH7-(1526-1571) chimera protein | Authors: | Taylor, K.C, Korkmaz, E.N, Andreas, M.P, Ajay, G, Heinz, N.T, Cui, Q, Rayment, I. | Deposit date: | 2015-07-13 | Release date: | 2015-12-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A composite approach towards a complete model of the myosin rod. Proteins, 84, 2016
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5CJ4
| Crystal Structure of Amino Acids 1562-1622 of MYH7 | Descriptor: | Xrcc4-MYH7-(1562-1622) chimera protein | Authors: | Korkmaz, N.E, Taylor, K.C, Andreas, M.P, Ajay, G, Heinze, N.T, Cui, Q, Rayment, I. | Deposit date: | 2015-07-13 | Release date: | 2015-12-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | A composite approach towards a complete model of the myosin rod. Proteins, 84, 2016
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3BZ9
| Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II | Descriptor: | (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Allingham, J.S, Rayment, I. | Deposit date: | 2008-01-17 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
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3BZ8
| Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II | Descriptor: | (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Allingham, J.S, Rayment, I. | Deposit date: | 2008-01-17 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
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3BZ7
| Crystal Structures of (S)-(-)-Blebbistatin Analogs bound to Dictyostelium discoideum myosin II | Descriptor: | (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Allingham, J.S, Rayment, I. | Deposit date: | 2008-01-17 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design. Org.Biomol.Chem., 6, 2008
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1ZA0
| X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv | Descriptor: | 1,2-ETHANEDIOL, MANGANESE (II) ION, POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) | Authors: | Dyer, H.D, Lyle, K.S, Rayment, I, Fox, B.G. | Deposit date: | 2005-04-05 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv. Protein Sci., 14, 2005
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1YXQ
| Crystal structure of actin in complex with swinholide A | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Klenchin, V.A, King, R, Tanaka, J, Marriott, G, Rayment, I. | Deposit date: | 2005-02-22 | Release date: | 2005-05-17 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural basis of swinholide a binding to actin Chem.Biol., 12, 2005
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1YV3
| The structural basis of blebbistatin inhibition and specificity for myosin II | Descriptor: | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Allingham, J.S, Smith, R, Rayment, I. | Deposit date: | 2005-02-14 | Release date: | 2005-03-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structural basis of blebbistatin inhibition and specificity for myosin II. Nat.Struct.Mol.Biol., 12, 2005
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3MYH
| Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 | Descriptor: | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. | Deposit date: | 2010-05-10 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
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3MYL
| Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 | Descriptor: | MAGNESIUM ION, Myosin-2 heavy chain, PYROPHOSPHATE 2- | Authors: | Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. | Deposit date: | 2010-05-10 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
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3MTU
| Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Capsid assembly scaffolding protein,Tropomyosin alpha-1 chain, ... | Authors: | Klenchin, V.A, Frye, J, Rayment, I. | Deposit date: | 2010-04-30 | Release date: | 2010-06-23 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition . Biochemistry, 49, 2010
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3MUD
| Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle | Descriptor: | 1,2-ETHANEDIOL, DNA repair protein XRCC4,Tropomyosin alpha-1 chain, SULFATE ION, ... | Authors: | Klenchin, V.A, Frye, J, Rayment, I. | Deposit date: | 2010-05-02 | Release date: | 2010-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the tropomyosin overlap complex from chicken smooth muscle: insight into the diversity of N-terminal recognition . Biochemistry, 49, 2010
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3MYK
| Insights into the Importance of Hydrogen Bonding in the Gamma-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Ser236 | Descriptor: | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, MAGNESIUM ION, Myosin-2 heavy chain, ... | Authors: | Frye, J.J, Klenchin, V.A, Bagshaw, C.R, Rayment, I. | Deposit date: | 2010-05-10 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236 Biochemistry, 49, 2010
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2ASM
| Structure of Rabbit Actin In Complex With Reidispongiolide A | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Allingham, J.S, Zampella, A, D'Auria, M.V, Rayment, I. | Deposit date: | 2005-08-23 | Release date: | 2005-10-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity Proc.Natl.Acad.Sci.Usa, 102, 2005
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