7VEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vep by Molmil](/molmil-images/mine/7vep) | |
7FGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fgq by Molmil](/molmil-images/mine/7fgq) | |
6KDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kdu by Molmil](/molmil-images/mine/6kdu) | Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | Descriptor: | ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... | Authors: | Ramachandran, R, Shukla, A, Afsar, M. | Deposit date: | 2019-07-02 | Release date: | 2020-07-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
|
|
6KJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kjm by Molmil](/molmil-images/mine/6kjm) | Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | Descriptor: | ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... | Authors: | Ramachandran, R, Shukla, A, Afsar, M. | Deposit date: | 2019-07-22 | Release date: | 2020-07-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A. J.Struct.Biol., 213, 2021
|
|
6KKV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kkv by Molmil](/molmil-images/mine/6kkv) | |
6KSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ksd by Molmil](/molmil-images/mine/6ksd) | |
6KRH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6krh by Molmil](/molmil-images/mine/6krh) | Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | Descriptor: | ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ... | Authors: | Ramachandran, R, Shukla, A, Afsar, M. | Deposit date: | 2019-08-21 | Release date: | 2020-08-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity. Acta Crystallogr D Struct Biol, 77, 2021
|
|
6KSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ksc by Molmil](/molmil-images/mine/6ksc) | |
6LW8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lw8 by Molmil](/molmil-images/mine/6lw8) | Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | Descriptor: | (4R)-4-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, DNA ligase A, GLYCEROL, ... | Authors: | Ramachandran, R, Afsar, M, Shukla, A. | Deposit date: | 2020-02-07 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A. J.Struct.Biol., 213, 2021
|
|
5IS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5is2 by Molmil](/molmil-images/mine/5is2) | |
5T41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5t41 by Molmil](/molmil-images/mine/5t41) | |
4PCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pcq by Molmil](/molmil-images/mine/4pcq) | Crystal Structure of MtbAldR (Rv2779c) | Descriptor: | Possible transcriptional regulatory protein (Probably Lrp/AsnC-family) | Authors: | Dey, A, Ramachandran, R. | Deposit date: | 2014-04-16 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of MtbAldR To be published
|
|
1Z30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z30 by Molmil](/molmil-images/mine/1z30) | NMR structure of the apical part of stemloop D from cloverleaf 1 of bovine enterovirus 1 RNA | Descriptor: | 5'-R(*GP*GP*CP*GP*UP*UP*CP*GP*UP*UP*AP*GP*AP*AP*CP*GP*UP*C)-3' | Authors: | Ihle, Y, Ohlenschlager, O, Duchardt, E, Ramachandran, R, Gorlach, M. | Deposit date: | 2005-03-10 | Release date: | 2005-04-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A novel cGUUAg tetraloop structure with a conserved yYNMGg-type backbone conformation from cloverleaf 1 of bovine enterovirus 1 RNA Nucleic Acids Res., 33, 2005
|
|
5IT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5it4 by Molmil](/molmil-images/mine/5it4) | |
5JLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jlp by Molmil](/molmil-images/mine/5jlp) | |
5JJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jjb by Molmil](/molmil-images/mine/5jjb) | |
5JLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jlr by Molmil](/molmil-images/mine/5jlr) | Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, MAGNESIUM ION, ... | Authors: | Shree, S, Agrawal, A, Dubey, S, Ramachandran, R. | Deposit date: | 2016-04-27 | Release date: | 2017-05-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.261 Å) | Cite: | Crystal structure of Mycobacterium avium SerB2 with serine present at slightly different position near ACT domain To be published
|
|
5IT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5it0 by Molmil](/molmil-images/mine/5it0) | |
5JMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jma by Molmil](/molmil-images/mine/5jma) | Crystal structure of Mycobacterium avium SerB2 in complex with serine at catalytic (PSP) domain | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Phosphoserine phosphatase, ... | Authors: | Shree, S, Dubey, S, Agrawal, A, Ramachandran, R. | Deposit date: | 2016-04-28 | Release date: | 2017-05-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of Mycobacterium avium SerB2 in complex with serine at catalytic (PSP) domain To be published
|
|
3RB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rb9 by Molmil](/molmil-images/mine/3rb9) | |
3S5C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s5c by Molmil](/molmil-images/mine/3s5c) | Crystal Structure of a Hexachlorocyclohexane dehydrochlorinase (LinA) Type2 | Descriptor: | LinA | Authors: | Kukshal, V, Macwan, A.S, Kumar, A, Ramachandran, R. | Deposit date: | 2011-05-23 | Release date: | 2012-05-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of the hexachlorocyclohexane dehydrochlorinase (LinA-type2): mutational analysis, thermostability and enantioselectivity Plos One, 7, 2012
|
|
1M4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m4y by Molmil](/molmil-images/mine/1m4y) | Crystal structure of HslV from Thermotoga maritima | Descriptor: | ATP-dependent protease hslV, SODIUM ION | Authors: | Song, H.K, Ramachandran, R, Bochtler, M.B, Hartmann, C, Azim, M.K, Huber, R. | Deposit date: | 2002-07-05 | Release date: | 2003-05-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. BIOPHYS.CHEM., 100, 2003
|
|
1ZAU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zau by Molmil](/molmil-images/mine/1zau) | |
1S9L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s9l by Molmil](/molmil-images/mine/1s9l) | NMR Solution Structure of a Parallel LNA Quadruplex | Descriptor: | 5'-((TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3' | Authors: | Randazzo, A, Esposito, V, Ohlenschlager, O, Ramachandran, R, Mayola, L. | Deposit date: | 2004-02-05 | Release date: | 2004-06-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR solution structure of a parallel LNA quadruplex. Nucleic Acids Res., 32, 2004
|
|
1SSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ssn by Molmil](/molmil-images/mine/1ssn) | STAPHYLOKINASE, SAKSTAR VARIANT, NMR, 20 STRUCTURES | Descriptor: | STAPHYLOKINASE | Authors: | Ohlenschlager, O, Ramachandran, R, Guhrs, K.H, Schlott, B, Brown, L.R. | Deposit date: | 1998-06-07 | Release date: | 1998-12-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance solution structure of the plasminogen-activator protein staphylokinase. Biochemistry, 37, 1998
|
|