7Z1H
 
 | | VAR2CSA APO | | Descriptor: | VAR2CSA APO | | Authors: | Raghavan, S.S.R, Wang, K.T. | | Deposit date: | 2022-02-24 | | Release date: | 2022-11-02 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
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7Z12
 | | VAR2 complex with PAM1.4 | | Descriptor: | PAM1.4, Heavy Chain, light Chain, ... | | Authors: | Raghavan, S.S.R, Wang, K.T. | | Deposit date: | 2022-02-24 | | Release date: | 2022-11-02 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
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8P2E
 | | Homotypic interacting B1 fab bound to Chondroitin Sulfate A | | Descriptor: | B1 fab heavy, B1 fab light | | Authors: | Raghavan, S.S.R, Dagil, R, Wang, K.T, Salanti, A. | | Deposit date: | 2023-05-16 | | Release date: | 2024-06-05 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Nat Commun, 15, 2024
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9BHB
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8C5R
 | | Omicron B.1.1.529 2 RBD up conformation | | Descriptor: | Spike glycoprotein | | Authors: | Raghavan, S.S.R, Walker, M.R, Salanti, A, Barfod, L.K, Wang, K.T. | | Deposit date: | 2023-01-10 | | Release date: | 2024-01-24 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages.
Commun Biol, 7, 2024
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8VDG
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8VDF
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9FJK
 | | Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6 | | Descriptor: | K501SP6 Fv Heavy Chain, K501SP6 Fv Light Chain, Spike glycoprotein,Fibritin | | Authors: | Bjoernsson, K.H, Walker, M.R, Raghavan, S.S.R, Ward, A.B, Barfod, L.K. | | Deposit date: | 2024-05-31 | | Release date: | 2024-08-14 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages.
Commun Biol, 7, 2024
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8U1S
 | | A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ... | | Authors: | Ferguson, J.A, Raghavan, S.S.R, Ward, A.B. | | Deposit date: | 2023-09-02 | | Release date: | 2024-03-27 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.
Immunity, 57, 2024
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8C3Y
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8C44
 | | HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Raghavan, S.S.R, Lavstsen, T, Wang, K.T. | | Deposit date: | 2022-12-31 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
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8U1C
 | | A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-400 heavy chain, ... | | Authors: | Ferguson, J.A, Oeverdieck, S, Ward, A.B. | | Deposit date: | 2023-08-31 | | Release date: | 2024-03-27 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.
Immunity, 57, 2024
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8U1Q
 | | A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-2D10 heavy chain, ... | | Authors: | Ferguson, J.A, Oeverdieck, S, Ward, A.B. | | Deposit date: | 2023-09-01 | | Release date: | 2024-03-27 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Isolation of human antibodies against influenza B neuraminidase and mechanisms of protection at the airway interface.
Immunity, 57, 2024
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8VDL
 | | HB3VAR03 CIDRa1.4 domain with C7 Fab | | Descriptor: | C7 Heavy Chain, C7 Light Chain, HB3VAR03 CIDRa1.4 domain, ... | | Authors: | Hurlburt, N.K, Pancera, M. | | Deposit date: | 2023-12-15 | | Release date: | 2024-10-09 | | Last modified: | 2025-01-15 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Broadly inhibitory antibodies to severe malaria virulence proteins.
Nature, 636, 2024
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