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7WCM
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BU of 7wcm by Molmil
Cryo-EM structure of GPR119-Gs Complex with small molecule agonist MBX-2982
Descriptor: 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Qiao, A.N, Wu, S, Ye, S.
Deposit date:2021-12-20
Release date:2022-12-21
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (2.33 Å)
Cite:Activation and signaling mechanism revealed by GPR119-G s complex structures.
Nat Commun, 13, 2022
7WCN
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BU of 7wcn by Molmil
Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453
Descriptor: Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Qiao, A.N, Wu, S, Ye, S.
Deposit date:2021-12-20
Release date:2022-12-21
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Activation and signaling mechanism revealed by GPR119-G s complex structures.
Nat Commun, 13, 2022

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