3L4C
| Structural basis of membrane-targeting by Dock180 | Descriptor: | BETA-MERCAPTOETHANOL, Dedicator of cytokinesis protein 1 | Authors: | Premkumar, L, Bobkov, A.A, Patel, M, Jaroszewski, L, Bankston, L.A, Stec, B, Vuori, K, Cote, J.-F, Liddington, R.C. | Deposit date: | 2009-12-18 | Release date: | 2010-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural basis of membrane targeting by the Dock180 family of Rho family guanine exchange factors (Rho-GEFs). J.Biol.Chem., 285, 2010
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3SF8
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1Y7V
| X-ray structure of human acid-beta-glucosidase covalently bound to conduritol B epoxide | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... | Authors: | Premkumar, L, Sawkar, A.R, Boldin-Adamsky, S, Toker, L, Silman, I, Kelly, J.W, Futerman, A.H, Sussman, J.L, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2004-12-10 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease. J.Biol.Chem., 280, 2005
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4K6X
| Crystal structure of disulfide oxidoreductase from Mycobacterium tuberculosis | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disulfide oxidoreductase | Authors: | Premkumar, L, Martin, J.L. | Deposit date: | 2013-04-16 | Release date: | 2013-10-02 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.972 Å) | Cite: | Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases. Acta Crystallogr.,Sect.D, 69, 2013
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1Y7W
| Crystal structure of a halotolerant carbonic anhydrase from Dunaliella salina | Descriptor: | ACETIC ACID, Halotolerant alpha-type carbonic anhydrase (dCA II), SODIUM ION, ... | Authors: | Premkumar, L, Greenblatt, H.M, Bageshwar, U.K, Savchenko, T, Gokhman, I, Sussman, J.L, Zamir, A, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2004-12-10 | Release date: | 2005-05-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Three-dimensional structure of a halotolerant algal carbonic anhydrase predicts halotolerance of a mammalian homolog. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4MLY
| Disulfide isomerase from multidrug resistance IncA/C related integrative and conjugative elements in oxidized state (P21 space group) | Descriptor: | 1,3-BUTANEDIOL, DsbP | Authors: | Premkumar, L, Kurth, F, Neyer, S, Martin, J.L. | Deposit date: | 2013-09-06 | Release date: | 2013-12-11 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.207 Å) | Cite: | The Multidrug Resistance IncA/C Transferable Plasmid Encodes a Novel Domain-swapped Dimeric Protein-disulfide Isomerase. J.Biol.Chem., 289, 2014
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4P3Y
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4ML6
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4ML1
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4TKY
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7T2Y
| X-ray structure of a designed cold unfolding four helix bundle | Descriptor: | Designed cold unfolding four helix bundle | Authors: | Harrison, J.S, Kuhlman, B, Szyperski, T, Premkumar, L, Maguire, J, Pulavarti, S, Yuen, S. | Deposit date: | 2021-12-06 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | From Protein Design to the Energy Landscape of a Cold Unfolding Protein. J.Phys.Chem.B, 126, 2022
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8DV6
| Zika virus envelope protein structure in complex with a potent Human mAb | Descriptor: | Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain | Authors: | Cameron, A, Puhl, A.C, deSilva, A.M, Premkumar, L. | Deposit date: | 2022-07-28 | Release date: | 2023-01-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus. Plos Pathog., 19, 2023
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6NEN
| Catalytic domain of Proteus mirabilis ScsC | Descriptor: | Copper resistance protein | Authors: | Kurth, F, Furlong, E.J, Premkumar, L, Martin, J.L. | Deposit date: | 2018-12-17 | Release date: | 2019-03-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis. Acta Crystallogr D Struct Biol, 75, 2019
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4XVW
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2MBS
| NMR solution structure of oxidized KpDsbA | Descriptor: | Thiol:disulfide interchange protein | Authors: | Kurth, F, Rimmer, K, Premkumar, L, Mohanty, B, Duprez, W, Halili, M.A, Shouldice, S.R, Heras, B, Fairlie, D.P, Scanlon, M.J, Martin, J.L. | Deposit date: | 2013-08-03 | Release date: | 2013-12-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes. Plos One, 8, 2013
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4MCU
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4OD7
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1ZKG
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6XRX
| Crystal structure of the mosquito protein AZ1 as an MBP fusion | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Pedersen, L.C, Mueller, G.A, Foo, A.C.Y. | Deposit date: | 2020-07-14 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism. Proc.Natl.Acad.Sci.USA, 118, 2021
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6EEZ
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6MHH
| Proteus mirabilis ScsC linker (residues 39-49) deletion and N6K mutant | Descriptor: | Metal resistance protein | Authors: | Furlong, E.J, Martin, J.L. | Deposit date: | 2018-09-17 | Release date: | 2019-03-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.083 Å) | Cite: | Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis. Acta Crystallogr D Struct Biol, 75, 2019
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6WY1
| Crystal structure of an engineered thermostable dengue virus 2 envelope protein dimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dengue 2 soluble recombinant envelope | Authors: | Kudlacek, S.T, Lakshmanane, P, Kuhlman, B. | Deposit date: | 2020-05-12 | Release date: | 2021-11-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies. Sci Adv, 7, 2021
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7YAR
| ZIKV_Fab_G9E | Descriptor: | E protein, M protein, heavy chain, ... | Authors: | Shu, B, Thiam-Seng, N, Lok, S. | Deposit date: | 2022-06-28 | Release date: | 2023-01-04 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus. Plos Pathog., 19, 2023
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5ID4
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5IDR
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