3P03
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4LLH
| Substrate bound outward-open state of the symporter BetP | 分子名称: | 2-(trimethyl-lambda~5~-arsanyl)ethanol, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, ... | 著者 | Perez, C, Faust, B, Ziegler, C. | 登録日 | 2013-07-09 | 公開日 | 2014-05-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na(+) coupling. Nat Commun, 5, 2014
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4DOJ
| Crystal structure of BetP in outward-facing conformation | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, CHOLINE ION, ... | 著者 | Perez, C, Ziegler, C. | 登録日 | 2012-02-09 | 公開日 | 2012-06-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP. Nature, 490, 2012
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6HRC
| Outward-facing PglK with ATPgammaS bound | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, WlaB protein | 著者 | Perez, C, Locher, K.P. | 登録日 | 2018-09-26 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation. Structure, 27, 2019
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5NBD
| PglK flippase in complex with inhibitory nanobody | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nanobody, WlaB protein | 著者 | Perez, C, Pardon, E, Steyaert, J, Locher, K.P. | 登録日 | 2017-03-01 | 公開日 | 2017-05-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody. Sci Rep, 7, 2017
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5C76
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5C73
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5C78
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7PAF
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6XVH
| carbonic anhydrase with bound arylsulfonamide- boronic acid | 分子名称: | (4-sulfamoylphenyl)boronic acid, Carbonic anhydrase 2, ZINC ION | 著者 | Perez, C, Zhang, B. | 登録日 | 2020-01-22 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | An easy to assemble, fully modulable, selectiv and
colorimetric artificial bio-sensor for fingerprintting
the recognition of neurotransmitters To Be Published
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1I6E
| SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE OXIDIZED STATE | 分子名称: | CYTOCHROME C552, HEME C | 著者 | Reincke, B, Perez, C, Pristovsek, P, Luecke, C, Ludwig, C, Loehr, F, Rogov, V.V, Ludwig, B, Rueterjans, H. | 登録日 | 2001-03-02 | 公開日 | 2001-10-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of the functional domain of Paracoccus denitrificans cytochrome c(552) in both redox states. Biochemistry, 40, 2001
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1I6D
| SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE REDUCED STATE | 分子名称: | CYTOCHROME C552, HEME C | 著者 | Reincke, B, Perez, C, Pristovsek, P, Luecke, C, Ludwig, C, Loehr, F, Rogov, V.V, Ludwig, B, Rueterjans, H. | 登録日 | 2001-03-02 | 公開日 | 2001-10-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of the functional domain of Paracoccus denitrificans cytochrome c(552) in both redox states. Biochemistry, 40, 2001
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7B0K
| membrane protein structure | 分子名称: | CHOLINE ION, Drug/metabolite transporter (DMT) superfamily permease | 著者 | Baerland, N, Perez, C. | 登録日 | 2020-11-20 | 公開日 | 2022-03-16 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Mechanistic basis of choline import involved in teichoic acids and lipopolysaccharide modification. Sci Adv, 8, 2022
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1JBH
| Solution structure of cellular retinol binding protein type-I in the ligand-free state | 分子名称: | CELLULAR RETINOL-BINDING PROTEIN TYPE I | 著者 | Franzoni, L, Luecke, C, Perez, C, Cavazzini, D, Rademacher, M, Ludwig, C, Spisni, A, Rossi, G.L, Rueterjans, H. | 登録日 | 2001-06-04 | 公開日 | 2002-06-19 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and backbone dynamics of Apo- and holo-cellular retinol-binding protein in solution. J.Biol.Chem., 277, 2002
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1KGL
| Solution structure of cellular retinol binding protein type-I in complex with all-trans-retinol | 分子名称: | CELLULAR RETINOL-BINDING PROTEIN TYPE I, RETINOL | 著者 | Franzoni, L, Luecke, C, Perez, C, Cavazzini, D, Rademacher, M, Ludwig, C, Spisni, A, Rossi, G.L, Rueterjans, H. | 登録日 | 2001-11-27 | 公開日 | 2002-06-19 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and Backbone Dynamics of Apo- and Holo-cellular Retinol-binding
Protein in Solution. J.Biol.Chem., 277, 2002
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3GZG
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6S7V
| Lipoteichoic acids flippase LtaA | 分子名称: | MFS transporter | 著者 | Zhang, B, Perez, C. | 登録日 | 2019-07-06 | 公開日 | 2020-04-22 | 最終更新日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | 主引用文献 | Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis. Nat.Struct.Mol.Biol., 27, 2020
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2VBO
| Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers | 分子名称: | 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ... | 著者 | Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. | 登録日 | 2007-09-14 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456, 2008
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2VBN
| Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers | 分子名称: | 5'-D(*AP*AP*AP*AP*GP*GP*CP*AP*GP*AP)-3', 5'-D(*AP*GP*GP*AP*TP*CP*CP*TP*AP*AP)-3', 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP)-3', ... | 著者 | Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. | 登録日 | 2007-09-14 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456, 2008
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2VBL
| Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers | 分子名称: | 5'-D(*DA*DA*DA*DA*DG*DG*DC*DA*DG*DAP)-3', 5'-D(*DA*DG*DG*DA*DT*DC*DC*DT*DA*DAP)-3', 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', ... | 著者 | Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. | 登録日 | 2007-09-14 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456, 2008
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2VBJ
| Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers | 分子名称: | 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ... | 著者 | Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. | 登録日 | 2007-09-14 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456, 2008
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4AIN
| Crystal structure of BetP with asymmetric protomers. | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, CITRATE ANION, ... | 著者 | Koshy, C, Ziegler, C, Yildiz, O. | 登録日 | 2012-02-10 | 公開日 | 2012-06-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Alternating-Access Mechanism in Conformationally Asymmetric Trimers of the Betaine Transporter Betp. Nature, 490, 2012
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3G3N
| PDE7A catalytic domain in complex with 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one | 分子名称: | 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | 著者 | Castano, T, Wang, H. | 登録日 | 2009-02-02 | 公開日 | 2009-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors Chemmedchem, 4, 2009
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4C7R
| Inward facing conformation of the trimeric betaine transporter BetP in complex with lipids | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, CHLORIDE ION, ... | 著者 | Koshy, C, Yildiz, O, Ziegler, C. | 登録日 | 2013-09-24 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Evidence for Functional Lipid Interactions in the Betaine Transporter Betp Embo J., 32, 2013
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8UG3
| Crystal structure of KHK-C and compound 23 | 分子名称: | 2-[(4P)-4-{2-[(2S)-2-methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl}-1H-pyrazol-1-yl]-1-(piperazin-1-yl)ethan-1-one, GLYCEROL, Ketohexokinase, ... | 著者 | Durbin, J.D, Guo, S.Y. | 登録日 | 2023-10-05 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor. J.Med.Chem., 66, 2023
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