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4FVM
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BU of 4fvm by Molmil
Crystal structure of yeast DNA polymerase alpha
分子名称: DNA polymerase alpha catalytic subunit A
著者Perera, R.L, Pellegrini, L.
登録日2012-06-29
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4FXD
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BU of 4fxd by Molmil
Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA
分子名称: DNA (5'-D(*TP*TP*TP*TP*CP*GP*CP*TP*GP*CP*CP*CP*GP*CP*CP*T)-3'), DNA polymerase alpha catalytic subunit A, RNA (5'-R(*AP*GP*GP*CP*GP*GP*GP*CP*AP*G)-3')
著者Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L.
登録日2012-07-03
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4FYD
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BU of 4fyd by Molmil
Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA and dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*GP*AP*GP*CP*GP*TP*G*TP*GP*TP*AP*CP*CP*CP*CP*TP*GP*CP*CP*CP*GP*CP*CP*G)-3'), DNA polymerase alpha catalytic subunit A, ...
著者Perera, R.L, Pellegrini, L.
登録日2012-07-04
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4B08
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BU of 4b08 by Molmil
Yeast DNA polymerase alpha, Selenomethionine protein
分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A
著者Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L.
登録日2012-06-29
公開日2013-02-27
最終更新日2013-05-01
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha
Elife, 2, 2013
2XKJ
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BU of 2xkj by Molmil
CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE)
分子名称: GLYCEROL, SULFATE ION, TOPOISOMERASE IV
著者Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D.
登録日2010-07-08
公開日2010-09-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
2XKK
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CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)
分子名称: 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA, MAGNESIUM ION, ...
著者Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D.
登録日2010-07-08
公開日2010-09-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
4BPX
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BU of 4bpx by Molmil
Crystal structure of human primase in complex with the primase- binding motif of DNA polymerase alpha
分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT, DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, ...
著者Kilkenny, M.L, Perera, R.L, Pellegrini, L.
登録日2013-05-28
公開日2013-09-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPU
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BU of 4bpu by Molmil
Crystal structure of human primase in heterodimeric form, comprising PriS and truncated PriL lacking the C-terminal Fe-S domain.
分子名称: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, GLYCEROL, ...
著者Kilkenny, M.L, Perera, R.L, Pellegrini, L.
登録日2013-05-28
公開日2013-09-25
最終更新日2013-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
4BPW
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BU of 4bpw by Molmil
Crystal structure of human primase bound to UTP
分子名称: DNA PRIMASE LARGE SUBUNIT, DNA PRIMASE SMALL SUBUNIT, MAGNESIUM ION, ...
著者Kilkenny, M.L, Perera, R.L, Pellegrini, L.
登録日2013-05-28
公開日2013-09-25
最終更新日2013-10-16
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
Proc.Natl.Acad.Sci.USA, 110, 2013
3LGB
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BU of 3lgb by Molmil
Crystal Structure of the Fe-S Domain of the yeast DNA primase
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA primase large subunit, GLYCEROL, ...
著者Sauguet, L, Pellegrini, L.
登録日2010-01-20
公開日2010-04-21
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase
PLOS ONE, 5, 2010
6I52
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BU of 6i52 by Molmil
Yeast RPA bound to ssDNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Replication factor A protein 1, Replication factor A protein 2, ...
著者Yates, L.A, Aramayo, R.J, Zhang, X.
登録日2018-11-12
公開日2018-12-19
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
Nat Commun, 9, 2018
5NXQ
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BU of 5nxq by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP
分子名称: DNA polymerase alpha-binding protein, GLYCEROL, MET-ASP-ILE-UA1-ILE-ASP-ASP-ILE-LEU-UA2-GLU-LEU-ASP-LYS-GLU
著者Wu, Y, Pellegrini, L.
登録日2017-05-10
公開日2017-08-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.413 Å)
主引用文献Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.
Angew. Chem. Int. Ed. Engl., 56, 2017
4C93
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BU of 4c93 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha.
分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A, DNA POLYMERASE ALPHA-BINDING PROTEIN
著者Simon, A.C, Pellegrini, L.
登録日2013-10-02
公開日2014-04-30
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.694 Å)
主引用文献A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C95
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BU of 4c95 by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5
分子名称: DNA POLYMERASE ALPHA-BINDING PROTEIN, DNA REPLICATION COMPLEX GINS PROTEIN SLD5
著者Simon, A.C, Pellegrini, L.
登録日2013-10-02
公開日2014-04-30
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.694 Å)
主引用文献A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C8S
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BU of 4c8s by Molmil
Crystal structure of the C-terminal region of yeast Ctf4
分子名称: DNA POLYMERASE ALPHA-BINDING PROTEIN
著者Simon, A.C, Pellegrini, L.
登録日2013-10-01
公開日2014-04-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase a in the Eukaryotic Replisome
Nature, 510, 2014
4C8H
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BU of 4c8h by Molmil
Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein.
分子名称: CTF4
著者Simon, A.C, Pellegrini, L.
登録日2013-10-01
公開日2014-04-30
最終更新日2014-06-18
実験手法X-RAY DIFFRACTION (2.691 Å)
主引用文献A Ctf4 Trimer Couples the Cmg Helicase to DNA Polymerase Alpha in the Eukaryotic Replisome
Nature, 510, 2014
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
分子名称: DNA polymerase alpha-binding protein, Dna2p
著者Simon, A.C, Pellegrini, L.
登録日2016-01-19
公開日2016-06-22
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (3.092 Å)
主引用文献Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HOI
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BU of 5hoi by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
分子名称: DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
著者Simon, A.C, Pellegrini, L.
登録日2016-01-19
公開日2016-06-22
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016

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