Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4MEZ
DownloadVisualize
BU of 4mez by Molmil
Crystal structure of M68L/M69T double mutant TEM-1
分子名称: Beta-lactamase TEM, CHLORIDE ION, GLYCEROL, ...
著者Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M.
登録日2013-08-27
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.
Sci Rep, 9, 2019
4QY6
DownloadVisualize
BU of 4qy6 by Molmil
Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations
分子名称: Beta-lactamase TEM, Beta-lactamase PSE-4, CHLORIDE ION, ...
著者Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M.
登録日2014-07-23
公開日2015-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations
To be Published
4R4R
DownloadVisualize
BU of 4r4r by Molmil
Crystal structure of chimeric beta-lactamase cTEM-19m at 1.2 angstrom resolution
分子名称: Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION
著者Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M.
登録日2014-08-19
公開日2015-11-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.
Sci Rep, 9, 2019
4R4S
DownloadVisualize
BU of 4r4s by Molmil
Crystal structure of chimeric beta-lactamase cTEM-19m at 1.1 angstrom resolution
分子名称: Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION
著者Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M.
登録日2014-08-19
公開日2015-11-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.
Sci Rep, 9, 2019
4QY5
DownloadVisualize
BU of 4qy5 by Molmil
Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations
分子名称: Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION
著者Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M.
登録日2014-07-23
公開日2015-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations
To be Published
4ID4
DownloadVisualize
BU of 4id4 by Molmil
Crystal structure of chimeric beta-lactamase cTEM-17m
分子名称: Beta-lactamase TEM, Beta-lactamase PSE-4, CHLORIDE ION, ...
著者Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M.
登録日2012-12-11
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins.
Chem.Biol., 21, 2014
3EIG
DownloadVisualize
BU of 3eig by Molmil
Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase
分子名称: CADMIUM ION, Dihydrofolate reductase, METHOTREXATE, ...
著者Yachnin, B.J, Berghuis, A.M.
登録日2008-09-15
公開日2009-05-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.
J.Biol.Chem., 284, 2009
3SFM
DownloadVisualize
BU of 3sfm by Molmil
Novel crystallization conditions for tandem variant R67 DHFR yields wild-type crystal structure
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Dihydrofolate reductase type 2
著者Yachnin, B.J, Berghuis, A.M.
登録日2011-06-13
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure.
Acta Crystallogr.,Sect.F, 67, 2011
6NY0
DownloadVisualize
BU of 6ny0 by Molmil
Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(4-{3-[4-(6-carboxy-1H-benzimidazol-2-yl)phenoxy]-2-hydroxypropoxy}phenyl)-1H-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ...
著者Yachnin, B.J, Berghuis, A.M.
登録日2019-02-10
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Acs Omega, 4, 2019
6NXZ
DownloadVisualize
BU of 6nxz by Molmil
Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-[4-[(2~{R})-4-[4-(6-carboxy-1~{H}-benzimidazol-2-yl)phenoxy]-2-oxidanyl-butoxy]phenyl]-1~{H}-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ...
著者Yachnin, B.J, Berghuis, A.M.
登録日2019-02-10
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Acs Omega, 4, 2019

218853

件を2024-04-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon