8H1I
 
 | | Crystal structure of PlyGRCS, a bacteriophage Endolysin in complex with Cold shock protein C | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Cold shock-like protein CspC, ... | | 著者 | Padmanabhan, B, Gopinatha, K, Mandal, M, Saranya, G, Sudhagar, B. | | 登録日 | 2022-10-03 | | 公開日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of PlyGRCS, a bacteriophage Endolysin in complex with Cold shock protein C
To Be Published
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4YZO
 | | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Padmanabhan, B, Manjula, R, Yokoyama, S, Bessho, Y. | | 登録日 | 2015-03-25 | | 公開日 | 2016-03-30 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii
To Be Published
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7EXI
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1X2J
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-25 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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1X2R
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, Nuclear factor erythroid 2 related factor 2, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-26 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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1WG3
 | | Structural analysis of yeast nucleosome-assembly factor CIA1p | | 分子名称: | Anti-silencing protein 1 | | 著者 | Padmanabhan, B, Kataoka, K, Umehara, T, Adachi, N, Yokoyama, S, Horikoshi, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-27 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Similarity between Histone Chaperone Cia1p/Asf1p and DNA-Binding Protein NF-{kappa}B
J.Biochem.(Tokyo), 138, 2005
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1IMJ
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2YXH
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2YXG
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2Z32
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2YXD
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2ZAD
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2ZGI
 | | Crystal Structure of Putative 4-amino-4-deoxychorismate lyase | | 分子名称: | DI(HYDROXYETHYL)ETHER, PYRIDOXAL-5'-PHOSPHATE, Putative 4-amino-4-deoxychorismate lyase, ... | | 著者 | Padmanabhan, B, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-01-22 | | 公開日 | 2008-07-22 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structure of putative 4-amino-4-deoxychorismate lyase from Thermus thermophilus HB8.
Acta Crystallogr.,Sect.F, 65, 2009
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2ZG6
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2YXE
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2DWW
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2DZE
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2DVV
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2E3K
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1IXV
 | | Crystal Structure Analysis of homolog of oncoprotein gankyrin, an interactor of Rb and CDK4/6 | | 分子名称: | Probable 26S proteasome regulatory subunit p28 | | 著者 | Padmanabhan, B, Adachi, N, Kataoka, K, Horikoshi, M. | | 登録日 | 2002-07-09 | | 公開日 | 2003-12-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the homolog of the oncoprotein gankyrin, an interactor of Rb and CDK4/6
J.BIOL.CHEM., 279, 2004
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1KP0
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7XX3
 | | Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) | | 分子名称: | (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Padmanabhan, B, Unni, S. | | 登録日 | 2022-05-28 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published
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6LRZ
 | | Crystal structure of Keap1 in complex with dimethyl fumarate (DMF) | | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, Keap1-DC, ... | | 著者 | Padmanabhan, B, Unni, S, Deshmukh, P. | | 登録日 | 2020-01-16 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1.
Febs J., 288, 2021
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6JKE
 | | Discovery and the crystal structure of NS5 in complex with the N-terminal bromodomain of BRD2. | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 7-chloranyl-2-[(3-chlorophenyl)amino]pyrano[3,4-e][1,3]oxazine-4,5-dione, Bromodomain-containing protein 2, ... | | 著者 | Padmanabhan, B, Mathur, S, Deshmukh, P. | | 登録日 | 2019-02-28 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Novel pyrano 1,3 oxazine based ligand inhibits the epigenetic reader hBRD2 in glioblastoma.
Biochem.J., 477, 2020
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7ENZ
 | | Crystal structure of Phenanthredinone moiety in complex with the second bromodomain of BRD2 (BRD2-BD2). | | 分子名称: | Bromodomain-containing protein 2, TRIETHYLENE GLYCOL, phenanthridin-6(5H)-one | | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S. | | 登録日 | 2021-04-21 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural investigation of a pyrano-1,3-oxazine derivative and the phenanthridinone core moiety against BRD2 bromodomains.
Acta Crystallogr.,Sect.F, 78, 2022
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