3HHA
 
 | | Crystal structure of cathepsin L in complex with AZ12878478 | | 分子名称: | ACETATE ION, Cathepsin L1, GLYCEROL, ... | | 著者 | Asaad, N, Bethel, P.A, Coulson, M.D, Dawson, J, Ford, S.J, Gerhardt, S, Grist, M, Hamlin, G.A, James, M.J, Jones, E.V, Karoutchi, G.I, Kenny, P.W, Morley, A.D, Oldham, K, Rankine, N, Ryan, D, Wells, S.L, Wood, L, Augustin, M, Krapp, S, Simader, H, Steinbacher, S. | | 登録日 | 2009-05-15 | | 公開日 | 2009-06-23 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Dipeptidyl nitrile inhibitors of Cathepsin L.
Bioorg.Med.Chem.Lett., 19, 2009
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3HWN
 | | CATHEPSIN L with AZ13010160 | | 分子名称: | Cathepsin L1, Nalpha-[(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)carbonyl]-N-[(2E)-2-iminoethyl]-3-{5-[(Z)-iminomethyl]-1,3,4-oxadiazol-2-yl}-L-phenylalaninamide | | 著者 | Kenny, P, Morley, A. | | 登録日 | 2009-06-18 | | 公開日 | 2009-09-15 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Design of selective Cathepsin inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
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4TYH
 | | Ternary complex of P38 and MK2 with a P38 inhibitor | | 分子名称: | MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide | | 著者 | Cumming, J.G, Debreczeni, J.E, Edfeldt, F, Evertsson, F, Harrison, M, Holdgate, G, James, M, Lamont, S, Oldham, K, Sullivan, J.E, Wells, S. | | 登録日 | 2014-07-08 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Discovery of substrate selective, ATP-competitive P38 alpha MAP kinase inhibitors
To Be Published
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