1FIQ
 
 | | CRYSTAL STRUCTURE OF XANTHINE OXIDASE FROM BOVINE MILK | | 分子名称: | 2-HYDROXYBENZOIC ACID, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Enroth, C, Eger, B.T, Okamoto, K, Nishino, T, Nishino, T, Pai, E.F. | | 登録日 | 2000-08-04 | | 公開日 | 2000-10-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion.
Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
6LPG
 | | human VASH1-SVBP complex | | 分子名称: | SULFATE ION, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 1 | | 著者 | Ikeda, A, Nishino, T. | | 登録日 | 2020-01-10 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of the tetrameric human vasohibin-1-SVBP complex reveals a variable arm region within the structural core.
Acta Crystallogr D Struct Biol, 76, 2020
|
|
1QQ2
 | | CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23. | | 分子名称: | CHLORIDE ION, THIOREDOXIN PEROXIDASE 2 | | 著者 | Hirotsu, S, Abe, Y, Okada, K, Nagahara, N, Hori, H, Nishino, T, Hakoshima, T. | | 登録日 | 1999-06-10 | | 公開日 | 1999-10-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product.
Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1SIO
 | | Structure of Kumamolisin-As complexed with a covalently-bound inhibitor, AcIPF | | 分子名称: | Ace-ILE-PRO-PHL peptide inhibitor, CALCIUM ION, SULFATE ION, ... | | 著者 | Li, M, Wlodawer, A, Gustchina, A, Tsuruoka, N, Ashida, M, Minakata, H, Oyama, H, Oda, K, Nishino, T, Nakayama, T. | | 登録日 | 2004-03-01 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity
J.Biol.Chem., 279, 2004
|
|
1SIU
 | | KUMAMOLISIN-AS E78H MUTANT | | 分子名称: | CALCIUM ION, SULFATE ION, kumamolisin-As | | 著者 | Li, M, Wlodawer, A, Gustchina, A, Tsuruoka, N, Ashida, M, Minakata, H, Oyama, H, Oda, K, Nishino, T, Nakayama, T. | | 登録日 | 2004-03-01 | | 公開日 | 2004-03-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity
J.Biol.Chem., 279, 2004
|
|
1SN7
 | | KUMAMOLISIN-AS, APOENZYME | | 分子名称: | CALCIUM ION, kumamolisin-As | | 著者 | Wlodawer, A, Li, M, Gustchina, A, Oda, K, Nishino, T. | | 登録日 | 2004-03-10 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallographic and biochemical investigations of kumamolisin-as, a serine-carboxyl peptidase with collagenase activity.
J.Biol.Chem., 279, 2004
|
|
2E3T
 | | Crystal structure of rat xanthine oxidoreductase mutant (W335A and F336L) | | 分子名称: | BICARBONATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Asai, R, Nishino, T, Matsumura, T, Okamoto, K, Pai, E.F, Nishino, T. | | 登録日 | 2006-11-28 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase
J.Biochem.(Tokyo), 141, 2007
|
|
3BDJ
 | | Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor | | 分子名称: | CALCIUM ION, CARBONATE ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F, Nishino, T. | | 登録日 | 2007-11-14 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol.
Nucleosides Nucleotides Nucleic Acids, 27, 2008
|
|
1V97
 | | Crystal Structure of Bovine Milk Xanthine Dehydrogenase FYX-051 bound form | | 分子名称: | 4-(5-PYRIDIN-4-YL-1H-1,2,4-TRIAZOL-3-YL)PYRIDINE-2-CARBONITRILE, ACETIC ACID, CALCIUM ION, ... | | 著者 | Okamoto, K, Matsumoto, K, Hille, R, Eger, B.T, Pai, E.F, Nishino, T. | | 登録日 | 2004-01-21 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The crystal structure of xanthine oxidoreductase during catalysis: Implications for reaction mechanism and enzyme inhibition.
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1VDV
 | | Bovine Milk Xanthine Dehydrogenase Y-700 Bound Form | | 分子名称: | 1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-CARBOXYLIC ACID, ACETIC ACID, CALCIUM ION, ... | | 著者 | Fukunari, A, Okamoto, K, Nishino, T, Eger, B.T, Pai, E.F, Kamezawa, M, Yamada, I, Kato, N. | | 登録日 | 2004-03-25 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion
J.Pharmacol.Exp.Ther., 311, 2004
|
|
7DA0
 | |
7DA1
 | |
2Z9S
 | | Crystal Structure Analysis of rat HBP23/Peroxiredoxin I, Cys52Ser mutant | | 分子名称: | Peroxiredoxin-1 | | 著者 | Matsumura, T, Okamoto, K, Nishino, T, Abe, Y. | | 登録日 | 2007-09-25 | | 公開日 | 2007-11-20 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION
J.Biol.Chem., 283, 2008
|
|
2E1Q
 | | Crystal Structure of Human Xanthine Oxidoreductase mutant, Glu803Val | | 分子名称: | 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ... | | 著者 | Yamaguchi, Y, Matsumura, T, Ichida, K, Okamoto, K, Nishino, T. | | 登録日 | 2006-10-27 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate
J.Biochem.(Tokyo), 141, 2007
|
|
3UNC
 | | Crystal Structure of Bovine Milk Xanthine Dehydrogenase to 1.65A Resolution | | 分子名称: | 2-HYDROXYBENZOIC ACID, CALCIUM ION, CARBONATE ION, ... | | 著者 | Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F. | | 登録日 | 2011-11-15 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Protein conformational gating of enzymatic activity in xanthine oxidoreductase.
J.Am.Chem.Soc., 134, 2012
|
|
3UNI
 | | Crystal Structure of Bovine Milk Xanthine Dehydrogenase with NADH Bound | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-HYDROXYBENZOIC ACID, CALCIUM ION, ... | | 著者 | Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F. | | 登録日 | 2011-11-15 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Protein conformational gating of enzymatic activity in xanthine oxidoreductase.
J.Am.Chem.Soc., 134, 2012
|
|
3UNA
 | | Crystal Structure of Bovine Milk Xanthine Dehydrogenase with NAD Bound | | 分子名称: | 2-HYDROXYBENZOIC ACID, CALCIUM ION, CARBONATE ION, ... | | 著者 | Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F. | | 登録日 | 2011-11-15 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Protein conformational gating of enzymatic activity in xanthine oxidoreductase.
J.Am.Chem.Soc., 134, 2012
|
|
2ZRX
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and DMAPP. | | 分子名称: | DIMETHYLALLYL DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase, ... | | 著者 | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | 登録日 | 2008-09-01 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
|
|
2ZRZ
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN and DMAPP | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, DIMETHYLALLYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, ... | | 著者 | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | 登録日 | 2008-09-01 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
|
|
2ZRY
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN and IPP. | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, ... | | 著者 | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | 登録日 | 2008-09-01 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
|
|
2ZRV
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN. | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, Isopentenyl-diphosphate delta-isomerase | | 著者 | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | 登録日 | 2008-09-01 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
|
|
2ZRW
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN and IPP. | | 分子名称: | FLAVIN MONONUCLEOTIDE, ISOPENTYL PYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, ... | | 著者 | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | 登録日 | 2008-09-01 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
|
|
2ZRU
 | | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with FMN | | 分子名称: | FLAVIN MONONUCLEOTIDE, Isopentenyl-diphosphate delta-isomerase | | 著者 | Unno, H, Yamashita, S, Ikeda, Y, Sekiguchi, S, Yoshida, N, Yoshimura, T, Kusunoki, M, Nakayama, T, Nishino, T, Hemmi, H. | | 登録日 | 2008-09-01 | | 公開日 | 2009-01-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
|
|
3AM9
 | | Complex of bovine xanthine dehydrogenase and trihydroxy FYX-051 | | 分子名称: | 4-[5-(2,6-dioxo-1,2,3,6-tetrahydropyridin-4-yl)-1H-1,2,4-triazol-3-yl]-6-oxo-1,6-dihydropyridine-2-carbonitrile, BICARBONATE ION, CALCIUM ION, ... | | 著者 | Matsumoto, K, Okamoto, K, Ashizawa, N, Matsumura, T, Kusano, T, Nishino, T. | | 登録日 | 2010-08-18 | | 公開日 | 2010-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | FYX-051: A Novel and Potent Hybrid-Type Inhibitor of Xanthine Oxidoreductase
J.Pharmacol.Exp.Ther., 336, 2011
|
|
3AMZ
 | | Bovine Xanthine Oxidoreductase urate bound form | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BICARBONATE ION, CALCIUM ION, ... | | 著者 | Okamoto, K, Eger, B.T, Pai, E.F, Nishino, T. | | 登録日 | 2010-08-27 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate
J.Am.Chem.Soc., 132, 2010
|
|
