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1FWO
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BU of 1fwo by Molmil
THE SOLUTION STRUCTURE OF A 35-RESIDUE FRAGMENT FROM THE GRANULIN/EPITHELIN-LIKE SUBDOMAIN OF RICE ORYZAIN BETA (ROB 382-416 (C398S,C399S,C407S,C413S))
Descriptor: ORYZAIN BETA CHAIN
Authors:Tolkatchev, D, Xu, P, Ni, F.
Deposit date:2000-09-24
Release date:2001-05-09
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:A peptide derived from the C-terminal part of a plant cysteine protease folds into a stack of two beta-hairpins, a scaffold present in the emerging family of granulin-like growth factors.
J.Pept.Res., 57, 2001
4RWT
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BU of 4rwt by Molmil
Structure of actin-Lmod complex
Descriptor: Actin-5C, Leiomodin-2, MAGNESIUM ION, ...
Authors:Chen, X, Ni, F, Wang, Q.
Deposit date:2014-12-05
Release date:2015-10-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells.
Proc.Natl.Acad.Sci.USA, 112, 2015
3LUT
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BU of 3lut by Molmil
A Structural Model for the Full-length Shaker Potassium Channel Kv1.2
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ...
Authors:Chen, X, Ni, F, Wang, Q, Ma, J.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
1FGD
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BU of 1fgd by Molmil
EPIDERMAL GROWTH FACTOR (EGF) SUBDOMAIN OF HUMAN THROMBOMODULIN (NMR, 11 STRUCTURES)
Descriptor: THROMBOMODULIN
Authors:Hrabal, R, Komives, E.A, Ni, F.
Deposit date:1995-11-28
Release date:1996-06-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin.
Protein Sci., 5, 1996
1FGE
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BU of 1fge by Molmil
EPIDERMAL GROWTH FACTOR (EGF) SUBDOMAIN OF HUMAN THROMBOMODULIN (NMR, 14 STRUCTURES)
Descriptor: THROMBOMODULIN
Authors:Hrabal, R, Komives, E.A, Ni, F.
Deposit date:1995-11-28
Release date:1996-06-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structural resiliency of an EGF-like subdomain bound to its target protein, thrombin.
Protein Sci., 5, 1996
1G26
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BU of 1g26 by Molmil
THE SOLUTION STRUCTURE OF A WELL-FOLDED PEPTIDE BASED ON THE 31-RESIDUE AMINO-TERMINAL SUBDOMAIN OF HUMAN GRANULIN A
Descriptor: GRANULIN A
Authors:Tolkatchev, D, Ng, A, Vranken, W, Ni, F.
Deposit date:2000-10-17
Release date:2000-11-01
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Design and solution structure of a well-folded stack of two beta-hairpins based on the amino-terminal fragment of human granulin A.
Biochemistry, 39, 2000
1I8Y
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BU of 1i8y by Molmil
SEMI-AUTOMATIC STRUCTURE DETERMINATION OF THE CG1 3-30 PEPTIDE BASED ON ARIA
Descriptor: GRANULIN-1
Authors:Vranken, W.F, James, S, Bennett, H.P.J, Ni, F.
Deposit date:2001-03-16
Release date:2002-04-17
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structures of a 30-residue amino-terminal domain of the carp granulin-1 protein and its amino-terminally truncated 3-30 subfragment: implications for the conformational stability of the stack of two beta-hairpins.
Proteins, 47, 2002
1I8X
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BU of 1i8x by Molmil
SEMI-AUTOMATIC STRUCTURE DETERMINATION OF THE CG1 1-30 PEPTIDE BASED ON ARIA
Descriptor: GRANULIN-1
Authors:Vranken, W.F, James, S, Bennett, H.P.J, Ni, F.
Deposit date:2001-03-16
Release date:2002-04-17
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structures of a 30-residue amino-terminal domain of the carp granulin-1 protein and its amino-terminally truncated 3-30 subfragment: implications for the conformational stability of the stack of two beta-hairpins.
Proteins, 47, 2002
1IEH
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BU of 1ieh by Molmil
SOLUTION STRUCTURE OF A SOLUBLE SINGLE-DOMAIN ANTIBODY WITH HYDROPHOBIC RESIDUES TYPICAL OF A VL/VH INTERFACE
Descriptor: BRUC.D4.4
Authors:Vranken, W, Tolkatchev, D, Xu, P, Tanha, J, Chen, Z, Narang, S, Ni, F.
Deposit date:2001-04-09
Release date:2002-08-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a llama single-domain antibody with hydrophobic residues typical of the VH/VL interface.
Biochemistry, 41, 2002
1BFZ
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BU of 1bfz by Molmil
BOUND CONFORMATION OF N-TERMINAL CLEAVAGE PRODUCT PEPTIDE MIMIC (P1-P9 OF RELEASE SITE) WHILE BOUND TO HCMV PROTEASE AS DETERMINED BY TRANSFERRED NOESY EXPERIMENTS (P1-P5 SHOWN ONLY), NMR, 32 STRUCTURES
Descriptor: HCMV PROTEASE R-SITE N-TERMINAL CLEAVAGE PRODUCT
Authors:Laplante, S.R, Aubry, N, Bonneau, P.R, Cameron, D.R, Lagace, L, Massariol, M.-J, Montpetit, H, Ploufe, C, Kawai, S.H, Fulton, B.D, Chen, Z, Ni, F.
Deposit date:1998-05-25
Release date:1999-05-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Human cytomegalovirus protease complexes its substrate recognition sequences in an extended peptide conformation.
Biochemistry, 37, 1998
1QGM
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BU of 1qgm by Molmil
THE SOLUTION STRUCTURE OF A 30 RESIDUE AMINO-TERMINAL DOMAIN OF THE CARP GRANULIN-1 PROTEIN.
Descriptor: PROTEIN (AMINO-TERMINAL CARP GRANULIN-1)
Authors:Vranken, W.F, Xu, P, Ni, F.
Deposit date:1999-05-01
Release date:1999-12-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:A 30-residue fragment of the carp granulin-1 protein folds into a stack of two beta-hairpins similar to that found in the native protein.
J.Pept.Res., 53, 1999
1X9X
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BU of 1x9x by Molmil
Solution Structure of Dimeric SAM Domain from MAPKKK Ste11
Descriptor: Serine/threonine-protein kinase STE11
Authors:Bhattacharjya, S, Xu, P, Gingras, R, Shaykhutdinov, R, Wu, C, Whiteway, M, Ni, F.
Deposit date:2004-08-24
Release date:2005-08-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex.
J.Mol.Biol., 344, 2004
4JHD
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BU of 4jhd by Molmil
Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu
Descriptor: Actin-5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, X, Ni, F, Wang, Q.
Deposit date:2013-03-04
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural basis of actin filament nucleation by tandem w domains.
Cell Rep, 3, 2013
2GI4
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BU of 2gi4 by Molmil
Solution Structure of the Low Molecular Weight Protein Tyrosine Phosphatase from Campylobacter jejuni.
Descriptor: possible phosphotyrosine protein phosphatase
Authors:Tolkatchev, D, Shaykhutdinov, R, Xu, P, Ni, F.
Deposit date:2006-03-28
Release date:2006-04-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Three-dimensional structure and ligand interactions of the low molecular weight protein tyrosine phosphatase from Campylobacter jejuni.
Protein Sci., 15, 2006
5XP5
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BU of 5xp5 by Molmil
C-Src in complex with ATP-Chf
Descriptor: MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-[(S)-fluoranyl-[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid
Authors:Duan, Y, Guo, M, Dai, S, Chen, L, Chen, Y.
Deposit date:2017-06-01
Release date:2018-02-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
5XP7
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BU of 5xp7 by Molmil
C-Src in complex with ATP-CHCl
Descriptor: GLYCEROL, MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Guo, M, Dai, S, Duan, Y, Chen, L, Chen, Y.
Deposit date:2017-06-01
Release date:2017-09-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.012 Å)
Cite:Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
1FVY
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BU of 1fvy by Molmil
SOLUTION STRUCTURE OF THE OSTEOGENIC 1-31 FRAGMENT OF THE HUMAN PARATHYROID HORMONE
Descriptor: PARATHYROID HORMONE
Authors:Chen, Z.
Deposit date:2000-09-20
Release date:2000-11-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the osteogenic 1-31 fragment of the human parathyroid hormone.
Biochemistry, 39, 2000
7X7D
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BU of 7x7d by Molmil
SARS-CoV-2 Delta RBD and Nb22
Descriptor: Nb22, Spike protein S1
Authors:Wang, Y, Ye, S.
Deposit date:2022-03-09
Release date:2022-04-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22).
Front Immunol, 13, 2022
7X7E
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BU of 7x7e by Molmil
SARS-CoV-2 RBD and Nb22
Descriptor: Nb22, Spike protein S1, TETRAETHYLENE GLYCOL
Authors:Wang, Y, Ye, S.
Deposit date:2022-03-09
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Short-Term Instantaneous Prophylaxis and Efficient Treatment Against SARS-CoV-2 in hACE2 Mice Conferred by an Intranasal Nanobody (Nb22).
Front Immunol, 13, 2022
1UCY
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BU of 1ucy by Molmil
THROMBIN COMPLEXED WITH FIBRINOPEPTIDE A ALPHA (RESIDUES 7-19). THREE COMPLEXES, ONE WITH EPSILON-THROMBIN AND TWO WITH ALPHA-THROMBIN
Descriptor: FIBRINOPEPTIDE A-ALPHA, THROMBIN
Authors:Martin, P, Edwards, B.
Deposit date:1996-08-30
Release date:1997-02-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues.
Biochemistry, 35, 1996
5WFN
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BU of 5wfn by Molmil
Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT)
Descriptor: Actin-5C, Leiomodin-2, MAGNESIUM ION, ...
Authors:Yurtsever, Z, Eck, M.J, Dominguez, R.
Deposit date:2017-07-12
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
1MKX
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BU of 1mkx by Molmil
THE CO-CRYSTAL STRUCTURE OF UNLIGANDED BOVINE ALPHA-THROMBIN AND PRETHROMBIN-2: MOVEMENT OF THE YPPW SEGMENT AND ACTIVE SITE RESIDUES UPON LIGAND BINDING
Descriptor: ALPHA-THROMBIN, PRETHROMBIN-2
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-03-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.
Protein Sci., 6, 1997
1MKW
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BU of 1mkw by Molmil
THE CO-CRYSTAL STRUCTURE OF UNLIGANDED BOVINE ALPHA-THROMBIN AND PRETHROMBIN-2: MOVEMENT OF THE YPPW SEGMENT AND ACTIVE SITE RESIDUES UPON LIGAND BINDING
Descriptor: ALPHA-THROMBIN, PRETHROMBIN-2
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-03-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.
Protein Sci., 6, 1997
1YCP
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BU of 1ycp by Molmil
THE CRYSTAL STRUCTURE OF FIBRINOGEN-AA PEPTIDE 1-23 (F8Y) BOUND TO BOVINE THROMBIN EXPLAINS WHY THE MUTATION OF PHE-8 TO TYROSINE STRONGLY INHIBITS NORMAL CLEAVAGE AT ARGININE-16
Descriptor: ALPHA THROMBIN, EPSILON THROMBIN, FIBRINOPEPTIDE A-ALPHA
Authors:Malkowski, M.G, Edwards, B.F.P.
Deposit date:1997-05-01
Release date:1998-05-06
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16.
Biochem.J., 326, 1997
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