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6XPT
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BU of 6xpt by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to UDP
Descriptor: MAGNESIUM ION, Nucleoside diphosphate kinase, URIDINE-5'-DIPHOSPHATE
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-09
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
6XP4
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BU of 6xp4 by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293
Descriptor: Nucleoside diphosphate kinase
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
6XPS
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BU of 6xps by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside diphosphate kinase
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-08
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.644 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
6XPW
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BU of 6xpw by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to CDP
Descriptor: CYTIDINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase, PHOSPHATE ION
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-09
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
6XPV
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BU of 6xpv by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to dTDP
Descriptor: Nucleoside diphosphate kinase, THYMIDINE-5'-DIPHOSPHATE
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-09
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
6XPU
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BU of 6xpu by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to IDP
Descriptor: INOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside diphosphate kinase
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-09
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
6XP7
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BU of 6xp7 by Molmil
Nucleoside Diphosphate Kinase from Aspergillus fumgiatus Af293 bound to ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2020-07-08
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase.
Febs J., 288, 2021
7MO6
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BU of 7mo6 by Molmil
Guanosine Monophosphate Synthase from Aspergillus fumigatus Af293
Descriptor: GMP synthase [glutamine-hydrolyzing]
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-05-01
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus.
Acta Crystallogr D Struct Biol, 78, 2022
7RK4
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BU of 7rk4 by Molmil
Mannitol-2-dehydrogenase from Aspergillus fumigatus
Descriptor: Mannitol 2-dehydrogenase
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-07-22
Release date:2022-07-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Targeting the Mannitol Biosynthesis Pathway in Aspergillus fumigatus: Characterisation and Inhibition of Mannitol-2-Dehydrogenase
To Be Published
7RK5
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BU of 7rk5 by Molmil
Mannitol-2-dehydrogenase bound to NADH from Aspergillus fumigatus
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Mannitol 2-dehydrogenase
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Targeting the Mannitol Biosynthesis Pathway in Aspergillus fumigatus: Characterisation and Inhibition of Mannitol-2-Dehydrogenase
To Be Published
7RI0
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BU of 7ri0 by Molmil
Aspergillus fumigatus Enolase Bound to Phosphoenolpyruvate and 2-Phosphoglycerate
Descriptor: 2-PHOSPHOGLYCERIC ACID, Enolase, MAGNESIUM ION, ...
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-07-19
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural model of the human plasminogen and Aspergillus fumigatus enolase complex.
Proteins, 90, 2022
7RHV
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BU of 7rhv by Molmil
Aspergillus fumigatus Enolase
Descriptor: Enolase, MAGNESIUM ION
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-07-19
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural model of the human plasminogen and Aspergillus fumigatus enolase complex.
Proteins, 90, 2022
7RHW
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BU of 7rhw by Molmil
Aspergillus fumigatus Enolase Bound to 2-Phosphoglycerate
Descriptor: 2-PHOSPHOGLYCERIC ACID, Enolase, MAGNESIUM ION
Authors:Nguyen, S, Bruning, J.B.
Deposit date:2021-07-19
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural model of the human plasminogen and Aspergillus fumigatus enolase complex.
Proteins, 90, 2022
3VD0
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BU of 3vd0 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
Descriptor: DNA (5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3'), Tumor protein p73, ZINC ION
Authors:Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
Deposit date:2012-01-04
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VD1
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BU of 3vd1 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
Descriptor: DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), Tumor protein p73, ZINC ION
Authors:Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
Deposit date:2012-01-04
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VD2
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BU of 3vd2 by Molmil
structure of p73 DNA binding domain tetramer modulates p73 transactivation
Descriptor: DNA (5'-D(*AP*TP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*AP*T)-3'), Tumor protein p73, ZINC ION
Authors:Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H.
Deposit date:2012-01-04
Release date:2012-04-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Proc.Natl.Acad.Sci.USA, 109, 2012
7KH5
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BU of 7kh5 by Molmil
Hen Egg White Lysozyme in complex with tetrabromoterephthalic acid
Descriptor: 2,3,5,6-tetrabromobenzene-1,4-dicarboxylic acid, Lysozyme C
Authors:Truong, J, Nguyen, S.
Deposit date:2020-10-20
Release date:2021-04-28
Last modified:2021-05-19
Method:X-RAY DIFFRACTION (1.295 Å)
Cite:Simplified heavy-atom derivatization of protein structures via co-crystallization with the MAD tetragon tetrabromoterephthalic acid.
Acta Crystallogr.,Sect.F, 77, 2021
5QC4
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BU of 5qc4 by Molmil
Crystal structure of human Cathepsin-S with bound ligand
Descriptor: 2-[5-[5-ethanoyl-1-[(2~{R})-2-oxidanyl-3-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]propyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-3-yl]-2-(trifluoromethyl)phenyl]sulfanyl-1-pyrrolidin-1-yl-ethanone, Cathepsin S
Authors:Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K.
Deposit date:2017-08-04
Release date:2017-12-20
Last modified:2021-11-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
6OLJ
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BU of 6olj by Molmil
CryoEM structure of PilB from Geobacter metallireducens: C2ccocco conformation
Descriptor: Type IV pilus biogenesis ATPase PilB
Authors:McCallum, M, Howell, P.L.
Deposit date:2019-04-16
Release date:2019-11-20
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Multiple conformations facilitate PilT function in the type IV pilus.
Nat Commun, 10, 2019
6CWK
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BU of 6cwk by Molmil
Anti-RTA VHH antibody
Descriptor: 1,2-ETHANEDIOL, Anti-Ricin antibody, CHLORIDE ION, ...
Authors:Rudolph, M.J, Mantis, N.
Deposit date:2018-03-30
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.256 Å)
Cite:Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
6CWG
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BU of 6cwg by Molmil
Ricin catalytic subunit bound go A9 VHH antibody
Descriptor: CHLORIDE ION, Ricin, VHH antibody
Authors:Rudolph, M.J, Mantis, N.
Deposit date:2018-03-30
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31, 2018
5TXS
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BU of 5txs by Molmil
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-15 alpha chain, ...
Authors:Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
Deposit date:2016-11-17
Release date:2017-11-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
5VZ5
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BU of 5vz5 by Molmil
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
Deposit date:2017-05-26
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5901 Å)
Cite:A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
6AT9
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BU of 6at9 by Molmil
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101
Descriptor: ALK, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G.
Deposit date:2017-08-28
Release date:2018-03-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9503 Å)
Cite:A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
7MJ9
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BU of 7mj9 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide
Descriptor: Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, MHC class I antigen
Authors:Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
Deposit date:2021-04-19
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021

 

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數據於2024-05-15公開中

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