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3KJP
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BU of 3kjp by Molmil
Crystal Structure of hPOT1V2-GGTTAGGGTTAG
分子名称: 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1
著者Nandakumar, J, Cech, T.R, Podell, E.R.
登録日2009-11-03
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KJO
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BU of 3kjo by Molmil
Crystal Structure of hPOT1V2-dTrUd(AGGGTTAG)
分子名称: DNA/RNA (5'-D(*T)-R(P*U)-D(P*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Cech, T.R, Podell, E.R.
登録日2009-11-03
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
2HVQ
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BU of 2hvq by Molmil
Structure of Adenylated full-length T4 RNA Ligase 2
分子名称: Hypothetical 37.6 kDa protein in Gp24-hoc intergenic region, MAGNESIUM ION
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVS
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BU of 2hvs by Molmil
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 2'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVR
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BU of 2hvr by Molmil
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
8U8L
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BU of 8u8l by Molmil
X-ray crystal structure of TEBP-2 MCD3 with ds DNA
分子名称: CESIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*CP*A)-3'), ...
著者Nandakumar, J, Padmanaban, S.
登録日2023-09-18
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U8M
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BU of 8u8m by Molmil
X-ray crystal structure of TEBP-1 MCD2 homodimer
分子名称: COBALT (II) ION, Double-strand telomeric DNA-binding proteins 1
著者Nandakumar, J, Padmanaban, S.
登録日2023-09-18
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
7LDG
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BU of 7ldg by Molmil
Crystal structure of the MEILB2-BRCA2 complex
分子名称: Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein
著者Nandakumar, J, Pendlebury, D.F.
登録日2021-01-13
公開日2021-08-11
最終更新日2021-08-25
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites.
Nat.Struct.Mol.Biol., 28, 2021
7S3L
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BU of 7s3l by Molmil
Structure of Bacillus subtilis CcrZ (previously called YtmP)
分子名称: Aminoglycoside phosphotransferase family protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Nandakumar, J, Wozniak, K.J.
登録日2021-09-07
公開日2022-05-11
最終更新日2022-06-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and kinase activity of bacterial cell cycle regulator CcrZ.
Plos Genet., 18, 2022
8SH1
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BU of 8sh1 by Molmil
Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric double-stranded DNA duplex with a 3'-overhang
分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*CP*GP*CP*GP*CP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Tesmer, V.M.
登録日2023-04-13
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
8SH0
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BU of 8sh0 by Molmil
Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric DNA hairpin with a 3'-overhang
分子名称: ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Tesmer, V.M.
登録日2023-04-13
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
5WIR
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BU of 5wir by Molmil
Structure of the TRF1-TERB1 interface
分子名称: TERB1-TBM, Telomeric repeat-binding factor 1
著者Nandakumar, J, Pendlebury, D.F, Smith, E.M, Tesmer, V.M.
登録日2017-07-20
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dissecting the telomere-inner nuclear membrane interface formed in meiosis.
Nat. Struct. Mol. Biol., 24, 2017
5I2Y
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BU of 5i2y by Molmil
Crystal Structure of TPP1 K170A
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.M.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
5I2X
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BU of 5i2x by Molmil
Crystal Structure of TPP1 K170del
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
2OWO
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BU of 2owo by Molmil
Last Stop on the Road to Repair: Structure of E.coli DNA Ligase Bound to Nicked DNA-Adenylate
分子名称: 26-MER, 5'-D(*AP*CP*AP*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*C)-3', 5'-D(*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*G)-3', ...
著者Shuman, S, Nandakumar, J, Nair, P.A.
登録日2007-02-16
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Last Stop on the Road to Repair: Structure of E. coli DNA Ligase Bound to Nicked DNA-Adenylate.
Mol.Cell, 26, 2007
2FAR
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BU of 2far by Molmil
Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with dATP and Manganese
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MANGANESE (II) ION, SULFATE ION, ...
著者Zhu, H, Nandakumar, J, Aniukwu, J, Wang, L.K, Glickman, M.S, Lima, C.D, Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
8UN9
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BU of 8un9 by Molmil
Crystal structure of the MrfB exonuclease catalytic core
分子名称: Exonuclease MrfB, MAGNESIUM ION
著者Manthei, K.A, Nandakumar, J, Simmons, L.A.
登録日2023-10-18
公開日2024-05-01
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Structural and biochemical characterization of the mitomycin C repair exonuclease MrfB.
Nucleic Acids Res., 2024
2FAQ
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BU of 2faq by Molmil
Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain with ATP and Manganese
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, SULFATE ION, ...
著者Zhu, H, Nandakumar, J, Aniukwu, J, Wang, L.K, Glickman, M.S, Lima, C.D, Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAO
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BU of 2fao by Molmil
Crystal Structure of Pseudomonas aeruginosa LigD polymerase domain
分子名称: SULFATE ION, probable ATP-dependent DNA ligase
著者Zhu, H, Nandakumar, J, Aniukwu, J, Wang, L.K, Glickman, M.S, Lima, C.D, Shuman, S.
登録日2005-12-07
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2Q2T
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BU of 2q2t by Molmil
Structure of Chlorella virus DNA ligase-adenylate bound to a 5' phosphorylated nick
分子名称: 5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*C)-3', 5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3', 5'-D(P*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3', ...
著者Lima, C.D, Nandakumar, J, Nair, P.A, Smith, P, Shuman, S.
登録日2007-05-29
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for nick recognition by a minimal pluripotent DNA ligase.
Nat.Struct.Mol.Biol., 14, 2007
2Q2U
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Structure of Chlorella virus DNA ligase-product DNA complex
分子名称: 5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*CP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3', 5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3', Chlorella virus DNA ligase
著者Lima, C.D, Nandakumar, J, Nair, P.A, Smith, P, Shuman, S.
登録日2007-05-29
公開日2007-07-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for nick recognition by a minimal pluripotent DNA ligase.
Nat.Struct.Mol.Biol., 14, 2007

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