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6LXF
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BU of 6lxf by Molmil
Aromatic interactions drive the coupled folding and binding of the intrinsically disordered Sesbania mosaic virus VPg protein.
Descriptor: Polyprotein
Authors:Dixit, K, Karanth, N.M, Nair, S, Kumari, K, Chakrabarti, K.S, Savithri, H.S, Sarma, S.P.
Deposit date:2020-02-11
Release date:2021-01-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Aromatic Interactions Drive the Coupled Folding and Binding of the Intrinsically Disordered Sesbania mosaic Virus VPg Protein.
Biochemistry, 59, 2020
6M78
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BU of 6m78 by Molmil
Aromatic interactions drive the coupled folding and binding of the intrinsically disordered Sesbania mosaic virus VPg protein
Descriptor: Polyprotein
Authors:Dixit, K, Karanth, N.M, Nair, S, Kumari, K, Chakraborti, K.S, Savithri, H.S, Sarma, S.P.
Deposit date:2020-03-17
Release date:2021-01-27
Method:SOLUTION NMR
Cite:Aromatic Interactions Drive the Coupled Folding and Binding of the Intrinsically Disordered Sesbania mosaic Virus VPg Protein.
Biochemistry, 59, 2020
5UY9
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BU of 5uy9 by Molmil
Prolyl isomerase Pin1 R14A mutant bound with Brd4 peptide
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Brd4 peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ...
Authors:Dong, S.-H, Nair, S.
Deposit date:2017-02-23
Release date:2017-04-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4.
Oncogene, 36, 2017
6VQL
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BU of 6vql by Molmil
CRYSTAL STRUCTURE OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 (IRAK4-WT) COMPLEX WITH A NICOTINAMIDE INHIBITOR
Descriptor: 6-[(1,3-benzothiazol-6-yl)amino]-4-(cyclopropylamino)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]pyridine-3-carboxamide, Interleukin-1 receptor-associated kinase 4, SULFATE ION
Authors:Sack, J.S.
Deposit date:2020-02-05
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.069 Å)
Cite:Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Acs Med.Chem.Lett., 11, 2020
6LXY
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BU of 6lxy by Molmil
IRAK4 in complex with inhibitor
Descriptor: Interleukin-1 receptor-associated kinase 4, N-[(2R)-2-fluoranyl-3-methyl-3-oxidanyl-butyl]-6-[(6-fluoranylpyrazolo[1,5-a]pyrimidin-5-yl)amino]-4-(propan-2-ylamino)pyridine-3-carboxamide, SULFATE ION
Authors:Ghosh, K, Bose, S.
Deposit date:2020-02-12
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Acs Med.Chem.Lett., 11, 2020
1V1P
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BU of 1v1p by Molmil
The structure SSL from Staphylococcus Aureus from an orthorhombic crystal form
Descriptor: Exotoxin 1
Authors:Briggs, D.C, Naylor, C.E.
Deposit date:2004-04-21
Release date:2004-07-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Relationships and Cellular Tropism of Staphylococcal Superantigen-Like Proteins
Infect.Immun., 72, 2004
4KV4
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BU of 4kv4 by Molmil
Brd4 Bromodomain 2 in Complex with Acetylated Rel Peptide
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Bromodomain-containing protein 4, Rel Peptide
Authors:Zhang, H, Nair, S.K.
Deposit date:2013-05-22
Release date:2013-06-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Brd4 maintains constitutively active NF-kappa B in cancer cells by binding to acetylated RelA.
Oncogene, 33, 2014
4KV1
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BU of 4kv1 by Molmil
Crystal Structure of Brd4 Bromodomain 1 in Complex with Acetylated Rel Peptide
Descriptor: Bromodomain-containing protein 4, Rel peptide
Authors:Zhang, H, Nair, S.K.
Deposit date:2013-05-22
Release date:2013-06-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Brd4 maintains constitutively active NF-kappa B in cancer cells by binding to acetylated RelA.
Oncogene, 33, 2014
1ZYO
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BU of 1zyo by Molmil
Crystal Structure of the Serine Protease Domain of Sesbania Mosaic Virus polyprotein
Descriptor: GLYCEROL, serine protease
Authors:Gayathri, P, Satheshkumar, P.S, Prasad, K, Savithri, H.S, Murthy, M.R.N.
Deposit date:2005-06-10
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the serine protease domain of Sesbania mosaic virus polyprotein and mutational analysis of residues forming the S1-binding pocket
Virology, 346, 2006
1I6V
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BU of 1i6v by Molmil
THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX
Descriptor: DNA-DIRECTED RNA POLYMERASE, MAGNESIUM ION, RIFAMPICIN, ...
Authors:Campbell, E.A, Korzheva, N, Mustaev, A, Murakami, K, Goldfarb, A, Darst, S.A.
Deposit date:2001-03-05
Release date:2001-04-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural mechanism for rifampicin inhibition of bacterial rna polymerase.
Cell(Cambridge,Mass.), 104, 2001

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