4YCN
| Crystal structure of the calcium pump with bound marine macrolide BLLB | 分子名称: | (4S,5E,8S,9E,11S,13E,15E,18R)-4-hydroxy-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]oxacyclooctadeca-5,9,13,15-tetraen-2-one, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | 著者 | Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C. | 登録日 | 2015-02-20 | 公開日 | 2016-01-13 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding Febs Lett., 589, 2015
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4YCM
| Crystal structure of the calcium pump with bound marine macrolide BLS | 分子名称: | (4S,5E,8S,9E,11S,13E,15E,18R)-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]-2-oxooxacyclooctadeca-5,9,13,15-tetraen-4-yl 3-O-methyl-beta-D-glucopyranoside, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | 著者 | Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C. | 登録日 | 2015-02-20 | 公開日 | 2016-01-13 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding Febs Lett., 589, 2015
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7W47
| Crystal structure of the gastric proton pump complexed with tegoprazan | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Potassium-transporting ATPase alpha chain 1, ... | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | 登録日 | 2021-11-26 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump. J.Med.Chem., 65, 2022
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7W4A
| Cryo-EM structure of the gastric proton pump complexed with revaprazan | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | 登録日 | 2021-11-26 | 公開日 | 2022-03-02 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump. J.Med.Chem., 65, 2022
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3NGO
| Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA | 分子名称: | 5'-D(*AP*AP*AP*A)-3', CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-12 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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3NGQ
| Crystal structure of the human CNOT6L nuclease domain | 分子名称: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-13 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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3NGN
| Crystal structure of the human CNOT6L nuclease domain in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, CCR4-NOT transcription complex subunit 6-like | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-12 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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3DJU
| Crystal structure of human BTG2 | 分子名称: | Protein BTG2 | 著者 | Yang, X, Morita, M, Wang, H, Suzuki, T, Bartlam, M, Yamamoto, T. | 登録日 | 2008-06-24 | 公開日 | 2008-11-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity Nucleic Acids Res., 36, 2008
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3DJN
| Crystal structure of mouse TIS21 | 分子名称: | Protein BTG2 | 著者 | Yang, X, Morita, M, Wang, H, Suzuki, T, Bartlam, M, Yamamoto, T. | 登録日 | 2008-06-24 | 公開日 | 2008-11-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity Nucleic Acids Res., 36, 2008
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6PGN
| PagF single mutant with GPP | 分子名称: | GERANYL DIPHOSPHATE, MAGNESIUM ION, PagF | 著者 | Nair, S.K, Hao, Y, Estrada, P. | 登録日 | 2019-06-24 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Single Amino Acid Switch Alters the Isoprene Donor Specificity in
Ribosomally Synthesized and Post-Translationally Modified Peptide
Prenyltransferases J. Am. Chem. Soc., 140, 2018
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6PGM
| PirF geranyltransferase | 分子名称: | PirF Geranyltransferase | 著者 | Nair, S.K, Hao, Y, Estrada, P. | 登録日 | 2019-06-24 | 公開日 | 2019-07-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases. J.Am.Chem.Soc., 140, 2018
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3A5P
| Crystal structure of hemagglutinin | 分子名称: | Haemagglutinin I | 著者 | Watanabe, N, Sakai, N, Nakamura, T, Nabeshima, Y, Kouno, T, Mizuguchi, M, Kawano, K. | 登録日 | 2009-08-10 | 公開日 | 2010-08-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | The Structure of Physarum polycephalum hemagglutinin I suggests a minimal carbohydrate recognition domain of legume lectin fold J.Mol.Biol., 405, 2011
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7W49
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7W48
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6KE0
| Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor | 分子名称: | 2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-1-[(2S)-2-methyl-1,2-dihydroimidazo[1,2-a]benzimidazol-3-yl]ethanone, MAGNESIUM ION, ZINC ION, ... | 著者 | Amano, Y, Honbou, K. | 登録日 | 2019-07-03 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors. Bioorg.Med.Chem., 27, 2019
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6KDX
| Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor | 分子名称: | MAGNESIUM ION, N-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]quinolin-2-amine, ZINC ION, ... | 著者 | Amano, Y, Honbou, K. | 登録日 | 2019-07-03 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors. Bioorg.Med.Chem., 27, 2019
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6KDZ
| Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor | 分子名称: | 4-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]-3,7,8,10-tetrazatricyclo[7.4.0.0^{2,7}]trideca-1,3,5,8,10,12-hexaen-6-ol, MAGNESIUM ION, ZINC ION, ... | 著者 | Amano, Y, Honbou, K. | 登録日 | 2019-07-03 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors. Bioorg.Med.Chem., 27, 2019
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5AON
| Crystal structure of the conserved N-terminal domain of Pex14 from Trypanosoma brucei | 分子名称: | PEROXIN 14, SULFATE ION | 著者 | Obita, T, Sugawara, Y, Mizuguchi, M, Watanabe, Y, Kawaguchi, K, Imanaka, T. | 登録日 | 2015-09-11 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.646 Å) | 主引用文献 | Characterization of the Interaction between Trypanosoma Brucei Pex5P and its Receptor Pex14P. FEBS Lett., 590, 2016
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5TTY
| PagF prenyltransferase | 分子名称: | DI(HYDROXYETHYL)ETHER, PagF prenyltransferase | 著者 | Hao, Y, Nair, S.K. | 登録日 | 2016-11-04 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5TU5
| PagF prenyltransferase with Tyr-Tyr-Tyr and DMSPP | 分子名称: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, PagF prenyltransferase, ... | 著者 | Hao, Y, Nair, S.K. | 登録日 | 2016-11-04 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5TU6
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5TU4
| PagF with Boc-Tyr and DMSPP | 分子名称: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, N-(tert-butoxycarbonyl)-L-tyrosine, ... | 著者 | Hao, Y, Nair, S.K. | 登録日 | 2016-11-04 | 公開日 | 2016-11-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular basis for the broad substrate selectivity of a peptide prenyltransferase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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