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2OSR
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BU of 2osr by Molmil
NMR Structure of RRM-2 of Yeast NPL3 Protein
分子名称: Nucleolar protein 3
著者Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G.
登録日2007-02-06
公開日2007-12-18
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals.
J.Mol.Biol., 375, 2008
2OSQ
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BU of 2osq by Molmil
NMR Structure of RRM-1 of Yeast NPL3 Protein
分子名称: Nucleolar protein 3
著者Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G.
登録日2007-02-06
公開日2007-12-18
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals.
J.Mol.Biol., 375, 2008
2J8P
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BU of 2j8p by Molmil
NMR structure of C-terminal domain of human CstF-64
分子名称: CLEAVAGE STIMULATION FACTOR 64 KDA SUBUNIT
著者Qu, X, Perez-Canadillas, J.M, Agrawal, S, De Baecke, J, Cheng, H, Varani, G, Moore, C.
登録日2006-10-27
公開日2006-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The C-Terminal Domains of Vertebrate Cstf-64 and its Yeast Orthologue RNA15 Form a New Structure Critical for Mrna 3'-End Processing.
J.Biol.Chem., 282, 2007
1RY6
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BU of 1ry6 by Molmil
Crystal Structure of Internal Kinesin Motor Domain
分子名称: INTERNAL KINESIN, SULFATE ION
著者Shipley, K, Hekmat-Nejad, M, Turner, J, Moores, C, Anderson, R, Milligan, R, Sakowicz, R, Fletterick, R.
登録日2003-12-19
公開日2004-04-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of a kinesin microtubule depolymerization machine.
Embo J., 23, 2004
4UXT
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BU of 4uxt by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN HEAVY CHAIN ISOFORM 5A, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXS
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BU of 4uxs by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXR
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BU of 4uxr by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UY0
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BU of 4uy0 by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXO
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BU of 4uxo by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXP
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BU of 4uxp by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-3 MOTOR DOMAIN, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
4UXY
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BU of 4uxy by Molmil
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
分子名称: ALPHA TUBULIN, BETA TUBULIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Atherton, J, Farabella, I, Yu, I.M, Rosenfeld, S.S, Houdusse, A, Topf, M, Moores, C.
登録日2014-08-27
公開日2014-09-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Conserved Mechanisms of Microtubule-Stimulated Adp Release, ATP Binding, and Force Generation in Transport Kinesins.
Elife, 3, 2014
6YW6
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BU of 6yw6 by Molmil
Cryo-EM structure of the ARP2/3 1B5CL isoform complex.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ARPC1B, Actin-related protein 2, ...
著者von Loeffelholz, O, Moores, C, Purkiss, A.
登録日2020-04-29
公開日2020-07-22
最終更新日2020-08-12
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biol Open, 9, 2020
6YW7
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BU of 6yw7 by Molmil
Cryo-EM structure of the ARP2/3 1A5C isoform complex.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ...
著者von Loeffelholz, O, Moores, C, Purkiss, A.
登録日2020-04-29
公開日2020-07-22
最終更新日2020-08-12
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biol Open, 9, 2020
6G76
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BU of 6g76 by Molmil
Phosphorylated RSK4 N-terminal Kinase Domain in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6, ZINC ION
著者Prischi, F, Ali, M.M.
登録日2018-04-04
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med, 13, 2021
6G78
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BU of 6g78 by Molmil
RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6
著者Prischi, F, Ali, M.M.
登録日2018-04-04
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med, 13, 2021
7OG3
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BU of 7og3 by Molmil
IRED-88
分子名称: NAD(P)-dependent oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION
著者Faller, M, Koch, E.
登録日2021-05-06
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Machine-Directed Evolution of an Imine Reductase for Activity and Stereoselectivity
Acs Catalysis, 2021
6G77
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BU of 6g77 by Molmil
RSK4 N-terminal Kinase Domain in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6, ZINC ION
著者Prischi, F, Ali, M.M.
登録日2018-04-04
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med, 13, 2021
5MM7
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BU of 5mm7 by Molmil
Ustilago maydis kinesin-5 motor domain with N-terminal extension in the AMPPNP state bound to microtubules
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Moores, C.A, von Loeffelholz, O.
登録日2016-12-08
公開日2018-08-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules.
J.Struct.Biol., 2019
5MM4
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BU of 5mm4 by Molmil
Ustilago maydis kinesin-5 motor domain in the AMPPNP state bound to microtubules
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Moores, C.A, von Loeffelholz, O.
登録日2016-12-08
公開日2018-06-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules.
J.Struct.Biol., 2019
4AQV
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BU of 4aqv by Molmil
Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.7-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the AMPPPNP state.
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
著者Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A.
登録日2012-04-19
公開日2012-11-21
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
4AQW
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BU of 4aqw by Molmil
Model of human kinesin-5 motor domain (1II6, 3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.5-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the rigor state.
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
著者Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A.
登録日2012-04-19
公開日2012-11-21
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
4CK6
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BU of 4ck6 by Molmil
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP.AlFx state, based on cryo-electron microscopy experiment.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C.
登録日2013-12-30
公開日2014-02-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.2 Å)
主引用文献Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CK7
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BU of 4ck7 by Molmil
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in presence of adp.alfx (NECK-LINKER IN ITS DISCONNECTED CONFORMATION, based on cryo-electron microscopy experiment
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C.
登録日2013-12-30
公開日2014-02-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9.2 Å)
主引用文献Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CK5
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BU of 4ck5 by Molmil
Pseudo-atomic model of microtubule-bound human kinesin-5 motor domain in the ADP state, based on cryo-electron microscopy experiment.
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Goulet, A, Major, J, Jun, Y, Gross, S, Rosenfeld, S, Moores, C.
登録日2013-12-30
公開日2014-02-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Comprehensive Structural Model of the Mechanochemical Cycle of a Mitotic Motor Highlights Molecular Adaptations in the Kinesin Family.
Proc.Natl.Acad.Sci.USA, 111, 2014
5MJS
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BU of 5mjs by Molmil
S. pombe microtubule copolymerized with GTP and Mal3-143
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Microtubule integrity protein mal3, ...
著者von Loeffelholz, O, Moores, C.
登録日2016-12-01
公開日2017-12-20
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics.
Nat Commun, 8, 2017

 

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