4ZBZ
 
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4ZBX
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4ZBY
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3AIZ
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3AIX
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4WN1
 | | Crystal structure of PDE10A in complex with 1-methyl-5-(1-methyl-3-{[4-(quinolin-2-yl)phenoxy]methyl}-1H-pyrazol-4-yl)pyridin-2(1H)-one | | 分子名称: | 1-methyl-5-(1-methyl-3-{[4-(quinolin-2-yl)phenoxy]methyl}-1H-pyrazol-4-yl)pyridin-2(1H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Amano, Y, Honbou, K. | | 登録日 | 2014-10-10 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition.
Bioorg.Med.Chem., 23, 2015
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4XY2
 | | Crystal structure of PDE10A in complex with ASP9436 | | 分子名称: | 1-methyl-5-(1-methyl-3-{[4-(1-methyl-1H-benzimidazol-4-yl)phenoxy]methyl}-1H-pyrazol-4-yl)pyridin-2(1H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Amano, Y, Honbou, K. | | 登録日 | 2015-02-02 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436
Bioorg.Med.Chem., 23, 2015
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1A99
 | | PUTRESCINE RECEPTOR (POTF) FROM E. COLI | | 分子名称: | 1,4-DIAMINOBUTANE, PUTRESCINE-BINDING PROTEIN | | 著者 | Vassylyev, D.G, Tomitori, H, Kashiwagi, K, Morikawa, K, Igarashi, K. | | 登録日 | 1998-04-17 | | 公開日 | 1998-10-21 | | 最終更新日 | 2020-04-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure and mutational analysis of the Escherichia coli putrescine receptor. Structural basis for substrate specificity.
J.Biol.Chem., 273, 1998
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1POY
 | | SPERMIDINE/PUTRESCINE-BINDING PROTEIN COMPLEXED WITH SPERMIDINE (DIMER FORM) | | 分子名称: | SPERMIDINE, SPERMIDINE/PUTRESCINE-BINDING PROTEIN | | 著者 | Sugiyama, S, Vassylyev, D.G, Matsushima, M, Morikawa, K. | | 登録日 | 1996-02-02 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli.
J.Biol.Chem., 271, 1996
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1POT
 | | SPERMIDINE/PUTRESCINE-BINDING PROTEIN COMPLEXED WITH SPERMIDINE (MONOMER FORM) | | 分子名称: | SPERMIDINE, SPERMIDINE/PUTRESCINE-BINDING PROTEIN | | 著者 | Sugiyama, S, Maenaka, K, Matsushima, M, Morikawa, K. | | 登録日 | 1996-02-02 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The 1.8-A X-ray structure of the Escherichia coli PotD protein complexed with spermidine and the mechanism of polyamine binding.
Protein Sci., 5, 1996
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5X52
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5YOQ
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3WI2
 | | Crystal structure of PDE10A in complex with inhibitor | | 分子名称: | 2-({[1-phenyl-2-(propan-2-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline, MAGNESIUM ION, ZINC ION, ... | | 著者 | Amano, Y. | | 登録日 | 2013-09-04 | | 公開日 | 2013-12-11 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition.
Bioorg.Med.Chem., 21, 2013
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