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Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
Descriptor:	Retinoblastoma-associated protein
Authors:	Hassler, M, Mittnacht, S, Pearl, L.H.
Deposit date:	2007-06-21
Release date:	2008-01-22
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol.Cell, 28, 2007

Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
Descriptor:	RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
Authors:	Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J.
Deposit date:	2002-12-16
Release date:	2003-03-06
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation Proc.Natl.Acad.Sci.USA, 100, 2003

Crystal structure of human Chk2 in complex with debromohymenialdisine
Descriptor:	DEBROMOHYMENIALDISINE, MAGNESIUM ION, NITRATE ION, ...
Authors:	Oliver, A.W, Pearl, L.H.
Deposit date:	2006-05-18
Release date:	2006-06-28
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Trans-Activation of the DNA-Damage Signalling Protein Kinase Chk2 by T-Loop Exchange Embo J., 25, 2006

Crystal structure of human Chk2 in complex with ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:	Oliver, A.W, Pearl, L.H.
Deposit date:	2006-05-18
Release date:	2006-06-28
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Trans-Activation of the DNA-Damage Signalling Protein Kinase Chk2 by T-Loop Exchange Embo J., 25, 2006