8G2N
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8TWH
| Crystal structure of (GGGTT)3GGG G-quadruplex in complex with small molecule ligand RHPS4 | Descriptor: | (GGGTT)3GGG DNA, 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, POTASSIUM ION | Authors: | Yatsunyk, L.A, Martin, K.N, Lam, G. | Deposit date: | 2023-08-21 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Crystal structure of (GGGTT)3GGG G-quadruplex in complex with small molecule ligand RHPS4 To be published
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8EBO
| Homopurine parallel G-quadruplex from human chromosome 7 stabilized by K+ ions | Descriptor: | COBALT (III) ION, DNA (5'-D(*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*A)-3'), N-METHYLMESOPORPHYRIN, ... | Authors: | Chen, E.V, Yatsunyk, L.A. | Deposit date: | 2022-08-31 | Release date: | 2022-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad. Bioorg.Med.Chem., 77, 2022
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8EDP
| Crystal structure of a three-tetrad, parallel, and K+ stabilized homopurine G-quadruplex from human chromosome 7 | Descriptor: | COBALT HEXAMMINE(III), DNA (5'-D(*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*AP*AP*GP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN, ... | Authors: | Ye, M, Yatsunyk, L.A. | Deposit date: | 2022-09-05 | Release date: | 2022-12-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad. Bioorg.Med.Chem., 77, 2022
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6XT7
| Tel25 Hybrid Four-quartet G-quadruplex with K+ | Descriptor: | DNA (25-MER), MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Yatsunyk, L.A, McCarthy, S.E. | Deposit date: | 2020-07-17 | Release date: | 2020-12-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The first crystal structures of hybrid and parallel four-tetrad intramolecular G-quadruplexes. Nucleic Acids Res., 50, 2022
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7JKU
| Crystal structure of a four-tetrad, parallel, and K+ stabilized Tetrahymena thermophila telomeric G-quadruplex | Descriptor: | 26-mer DNA, POTASSIUM ION | Authors: | Yatsunyk, L.A, McCarthy, S.E, Beseiso, D, Gallagher, E.P, Chen, E.V, Miao, J. | Deposit date: | 2020-07-28 | Release date: | 2021-07-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | The first crystal structures of hybrid and parallel four-tetrad intramolecular G-quadruplexes. Nucleic Acids Res., 50, 2022
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6W9P
| Tel26 Parallel Four-quartet G-quadruplex with K+ | Descriptor: | DNA (5'-D(P*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*TP*TP*GP*GP*GP*GP*T)-3'), POTASSIUM ION, SODIUM ION | Authors: | McCarthy, S.E, Yatsunyk, L.A, Beseiso, D, Miao, J. | Deposit date: | 2020-03-23 | Release date: | 2021-03-31 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The first crystal structures of hybrid and parallel four-tetrad intramolecular G-quadruplexes. Nucleic Acids Res., 50, 2022
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7LL0
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