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2PTU
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BU of 2ptu by Molmil
Structure of NK cell receptor 2B4 (CD244)
Descriptor: Natural killer cell receptor 2B4
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTV
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BU of 2ptv by Molmil
Structure of NK cell receptor ligand CD48
Descriptor: CD48 antigen
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
6WJU
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BU of 6wju by Molmil
Fab Fragment of Anti-human LAG3 antibody (4A10)
Descriptor: 4A10 Fab Heavy Chain, 4A10 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-14
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WK4
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BU of 6wk4 by Molmil
Fab Fragment of Anti-human LAG3 antibody (13E2)
Descriptor: 13E2 Fab Heavy Chain, 13E2 Fab Light Chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-15
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WKL
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BU of 6wkl by Molmil
Fab Fragment of Anti-human LAG3 antibody (BAP050)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Fab Fragment of Anti-human LAG3 antibody
To Be Published
6WKM
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BU of 6wkm by Molmil
Fab Fragment of Anti-human LAG3 antibody (22D2)
Descriptor: 22D2 Fab Heavy Chain, 22D2 Fab Light Chain
Authors:Agnihotri, P, Mishra, A.K, Mariuzza, R.A.
Deposit date:2020-04-16
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 2023
6X9X
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BU of 6x9x by Molmil
Crystal structure of Fab fragment of Anti-HCV E2 antibody (HC84.26)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, HC84.26 Fab Heavy Chain, ...
Authors:Shahid, S, Mariuzza, R.A.
Deposit date:2020-06-03
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Bivalent Antibody Fab Fragment.
J.Mol.Biol., 433, 2020
3L6F
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BU of 3l6f by Molmil
Structure of MHC class II molecule HLA-DR1 complexed with phosphopeptide MART-1
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2009-12-23
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4(+) T Cells.
J.Mol.Biol., 399, 2010
3M19
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BU of 3m19 by Molmil
Crystal structure of variable lymphocyte receptor VLRA.R5.1
Descriptor: Variable lymphocyte receptor A diversity region
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MC0
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BU of 3mc0 by Molmil
Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain
Descriptor: ACETATE ION, Enterotoxin SEG, variable beta 8.2 mouse T cell receptor
Authors:Fernandez, M.M, Cho, S, Robinson, H, Mariuzza, R.A, Malchiodi, E.L.
Deposit date:2010-03-26
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
3M18
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BU of 3m18 by Molmil
Crystal structure of variable lymphocyte receptor VLRA.R2.1 in complex with hen egg lysozyme
Descriptor: Lysozyme C, PHOSPHATE ION, Variable lymphocyte receptor A diversity region
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2010-03-04
Release date:2010-06-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey.
Proc.Natl.Acad.Sci.USA, 107, 2010
2EAV
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BU of 2eav by Molmil
Crystal structure of the C-terminal peptidoglycan-binding domain of human peptidoglycan recognition protein Ibeta
Descriptor: NICKEL (II) ION, Peptidoglycan recognition protein-I-beta
Authors:Cho, S, Mariuzza, R.A.
Deposit date:2007-02-03
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins
Proc.Natl.Acad.Sci.Usa, 104, 2007
4K79
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BU of 4k79 by Molmil
Recognition of the Thomsen-Friedenreich Antigen by a Lamprey Variable Lymphocyte Receptor
Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
Authors:Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
Deposit date:2013-04-16
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
4K5U
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BU of 4k5u by Molmil
Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor
Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose
Authors:Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
Deposit date:2013-04-15
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
2G9H
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BU of 2g9h by Molmil
Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule
Descriptor: 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ...
Authors:Fernandez, M.M, Guan, R, Malchiodi, E.L, Mariuzza, R.A.
Deposit date:2006-03-06
Release date:2006-07-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule.
J.Biol.Chem., 281, 2006
2IAL
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BU of 2ial by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAM
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BU of 2iam by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAN
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BU of 2ian by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
1JCK
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BU of 1jck by Molmil
T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SEC3 SUPERANTIGEN
Descriptor: 14.3.D T CELL ANTIGEN RECEPTOR, STAPHYLOCOCCAL ENTEROTOXIN C3
Authors:Fields, B.A, Mariuzza, R.A.
Deposit date:1996-10-22
Release date:1997-11-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a T-cell receptor beta-chain complexed with a superantigen.
Nature, 384, 1996
1BEC
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BU of 1bec by Molmil
BETA CHAIN OF A T CELL ANTIGEN RECEPTOR
Descriptor: 14.3.D T CELL ANTIGEN RECEPTOR
Authors:Bentley, G.A, Boulot, G, Karjalainen, K, Mariuzza, R.A.
Deposit date:1995-02-28
Release date:1995-10-25
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the beta chain of a T cell antigen receptor.
Science, 267, 1995
7RD2
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BU of 7rd2 by Molmil
Co-crystal structure of Chaetomium glucosidase with compound 2
Descriptor: (2R,3R,4R,5S)-1-{[4-({4-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-nitroanilino}methyl)phenyl]methyl}-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-07-09
Release date:2023-02-22
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity.
J.Med.Chem., 66, 2023
7T66
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BU of 7t66 by Molmil
Co-crystal structure of Chaetomium glucosidase with compound UV-4
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-13
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T6W
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BU of 7t6w by Molmil
Crystal structure of Chaetomium Glucosidase I (apo)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, GLYCEROL, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T8V
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BU of 7t8v by Molmil
Co-crystal structure of Chaetomium glucosidase I with EB-0159
Descriptor: (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-[(6-{[2-nitro-4-(1H-1,2,3-triazol-1-yl)phenyl]amino}hexyl)amino]cyclohexane-1,2,3,4-tetrol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-17
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T68
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BU of 7t68 by Molmil
Co-crystal structure of Chaetomium glucosidase with compound UV-5
Descriptor: (2R,3R,4R,5S)-1-[6-(4-azido-2-nitroanilino)hexyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-13
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022

219869

건을2024-05-15부터공개중

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