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6X9B
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BU of 6x9b by Molmil
Structure of proline utilization A with cis-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
分子名称: (4R)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-06-02
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X9C
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BU of 6x9c by Molmil
Structure of proline utilization A with L-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-06-02
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X99
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BU of 6x99 by Molmil
Structure of proline utilization A with D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
分子名称: Bifunctional protein PutA, D-PROLINE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-06-02
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X9A
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BU of 6x9a by Molmil
Structure of proline utilization A with trans-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
分子名称: (4S)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-06-02
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X9D
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BU of 6x9d by Molmil
Structure of proline utilization A with trans-4-hydroxy-L-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
分子名称: 4-HYDROXYPROLINE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-06-02
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
1WPQ
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BU of 1wpq by Molmil
Ternary Complex Of Glycerol 3-phosphate Dehydrogenase 1 with NAD and dihydroxyactone
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, ...
著者Ou, X, Han, X, Rao, Z.
登録日2004-09-10
公開日2006-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1)
J.Mol.Biol., 357, 2006
1X0V
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BU of 1x0v by Molmil
Crystal Structure of Homo Sapien Glycerol-3-Phosphate Dehydrogenase 1
分子名称: Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, SULFATE ION
著者Rao, Z, Ou, X.
登録日2005-03-30
公開日2006-04-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1)
J.Mol.Biol., 357, 2006
1X0X
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BU of 1x0x by Molmil
Co-Structure of Homo Sapiens Glycerol-3-Phosphate Dehydrogenase 1 complex with NAD
分子名称: Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Rao, Z, Ou, X.
登録日2005-03-31
公開日2006-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1)
J.Mol.Biol., 357, 2006
5W1R
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BU of 5w1r by Molmil
Cryo-EM structure of DNAPKcs
分子名称: DNA-dependent protein kinase catalytic subunit
著者Sharif, H, Li, Y, Wu, H.
登録日2017-06-04
公開日2017-07-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Cryo-EM structure of the DNA-PK holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6M1J
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BU of 6m1j by Molmil
The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12x
分子名称: 1-[5-[6-fluoranyl-8-(methylamino)-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]cyclopropane-1-carboxylic acid, DIMETHYL SULFOXIDE, DNA gyrase subunit B, ...
著者Xu, Z.H, Zhou, Z.
登録日2020-02-26
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.
J.Med.Chem., 63, 2020
6M1S
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BU of 6m1s by Molmil
The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12o
分子名称: 3-[5-[8-(ethylamino)-6-fluoranyl-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]oxy-2,2-dimethyl-propanoic acid, CHLORIDE ION, DNA gyrase subunit B, ...
著者Xu, Z.H, Zhou, Z.
登録日2020-02-26
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.254 Å)
主引用文献Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.
J.Med.Chem., 63, 2020
1HTV
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BU of 1htv by Molmil
CRYSTAL STRUCTURE OF DESTRIPEPTIDE (B28-B30) INSULIN
分子名称: INSULIN, ZINC ION
著者Ye, J, Chang, W, Liang, D.
登録日2001-01-01
公開日2001-05-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of destripeptide (B28-B30) insulin: implications for insulin dissociation.
Biochim.Biophys.Acta, 1547, 2001
3IWY
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BU of 3iwy by Molmil
Crystal structure of human MDM2 complexed with D-peptide (12 residues)
分子名称: D-peptide inhibitor, E3 ubiquitin-protein ligase Mdm2
著者Pazgier, M, Lu, W.
登録日2009-09-03
公開日2010-04-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms.
Proc.Natl.Acad.Sci.USA, 398, 2010
3D9H
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BU of 3d9h by Molmil
Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
分子名称: cDNA FLJ77766, highly similar to Homo sapiens ankyrin repeat and SOCS box-containing 9 (ASB9), transcript variant 2, ...
著者Fei, X, Gu, X, Fan, S, Zhang, C, Ji, C.
登録日2008-05-27
公開日2009-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Splice Variant of Human ASB9 (hASB9-2), an Ankyrin Repeat Protein
To be published
5T2P
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BU of 5t2p by Molmil
Hepatitis B virus core protein Y132A mutant in complex with sulfamoylbenzamide (SBA_R01)
分子名称: 4-fluoranyl-3-(4-oxidanylpiperidin-1-yl)sulfonyl-~{N}-[3,4,5-tris(fluoranyl)phenyl]benzamide, CHLORIDE ION, Core protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2016-08-24
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.693 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
5WTW
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BU of 5wtw by Molmil
Hepatitis B virus core protein Y132A mutant in P 41 21 2 Space Group
分子名称: CHLORIDE ION, Core protein
著者Zhou, Z, Xu, Z.H.
登録日2016-12-15
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
6JUE
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BU of 6jue by Molmil
The complex of PDZ and PBM
分子名称: Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU
著者Liu, Z.
登録日2019-04-13
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Par complex cluster formation mediated by phase separation.
Nat Commun, 11, 2020
5E1M
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BU of 5e1m by Molmil
Crystal structure of NTMT1 in complex with PPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-29
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E2A
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BU of 5e2a by Molmil
Crystal structure of NTMT1 in complex with N-terminally methylated SPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-30
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1B
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BU of 5e1b by Molmil
Crystal structure of NRMT1 in complex with SPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-29
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E2B
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BU of 5e2b by Molmil
Crystal structure of NTMT1 in complex with N-terminally methylated PPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-30
公開日2015-10-28
最終更新日2015-12-02
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1D
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BU of 5e1d by Molmil
NTMT1 in complex with YPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-29
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1O
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BU of 5e1o by Molmil
Crystal structure of NTMT1 in complex with RPKRIA peptide
分子名称: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-29
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
8UCX
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BU of 8ucx by Molmil
Dihydrofolate Reductase Complexed with Folate
分子名称: Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION
著者Fried, S.D.E, Boxer, S.G.
登録日2023-09-27
公開日2023-10-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Role of Electrostatics in Hydride Transfer by Dihydrofolate Reductase
To Be Published
6J1Z
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BU of 6j1z by Molmil
WWP2 semi-open conformation
分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP2
著者Liu, Z.H.
登録日2018-12-30
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Nat Commun, 10, 2019

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