6YWN
 
 | | CutA in complex with CMPCPP | | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, CALCIUM ION, CutA | | 著者 | Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M. | | 登録日 | 2020-04-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2020-09-30 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
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6YWP
 | | Structure of apo-CutA | | 分子名称: | CutA, MAGNESIUM ION | | 著者 | Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M. | | 登録日 | 2020-04-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2020-09-30 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
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6YWO
 | | CutA in complex with A3 RNA | | 分子名称: | CHLORIDE ION, CutA, MAGNESIUM ION, ... | | 著者 | Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M. | | 登録日 | 2020-04-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2020-09-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
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6STY
 | | Human REXO2 exonuclease in complex with RNA. | | 分子名称: | CALCIUM ION, Oligoribonuclease, mitochondrial, ... | | 著者 | Malik, D, Szewczyk, M, Szczesny, R, Nowotny, M. | | 登録日 | 2019-09-12 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA.
Nucleic Acids Res., 48, 2020
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8G87
 | | Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region) | | 分子名称: | POU domain, class 5, transcription factor 1, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G8E
 | | Human Oct4 bound to nucleosome with human LIN28B sequence | | 分子名称: | LIN28B DNA (32-MER), POU domain, class 5, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G8B
 | | Nucleosome with human nMatn1 sequence in complex with Human Oct4 | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G86
 | | Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome) | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G88
 | | Human Oct4 bound to nucleosome with human nMatn1 sequence | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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8G8G
 | | Interaction of H3 tail in LIN28B nucleosome with Oct4 | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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6QU5
 | | Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an allosteric inhibitor ctcb12 | | 分子名称: | 1-[(3,4-dichlorophenyl)methyl]imidazole, ATP-dependent 6-phosphofructokinase, CITRIC ACID, ... | | 著者 | McNae, I.W, Dornan, J, Walkinshaw, M.D. | | 登録日 | 2019-02-26 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Nat Commun, 12, 2021
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6QU3
 | | Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an allosteric inhibitor ctcb360 | | 分子名称: | 1-[(3,4-dichlorophenyl)methyl]-7~{H}-pyrrolo[3,2-c]pyridin-4-one, ATP-dependent 6-phosphofructokinase, CITRIC ACID, ... | | 著者 | McNae, I.W, Dornan, J, Walkinshaw, M.D. | | 登録日 | 2019-02-26 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Nat Commun, 12, 2021
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6QU4
 | | Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an allosteric inhibitor ctcb405 | | 分子名称: | 1-[(3,4-dichlorophenyl)methyl]-5-[2-(dimethylamino)ethyl]pyrrolo[3,2-c]pyridin-4-one, ATP-dependent 6-phosphofructokinase, CITRIC ACID, ... | | 著者 | McNae, I.W, Dornan, J, Walkinshaw, M.D. | | 登録日 | 2019-02-26 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Nat Commun, 12, 2021
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