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2QR7
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2.0A X-ray structure of C-terminal kinase domain of p90 ribosomal S6 kinase 2: Se-Met derivative
分子名称: Ribosomal protein S6 kinase alpha-3, SODIUM ION
著者Malakhova, M, Tereshko, V, Dong, Z.
登録日2007-07-27
公開日2007-12-11
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2.
Nat.Struct.Mol.Biol., 15, 2008
2QR8
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BU of 2qr8 by Molmil
2.0A X-ray structure of C-terminal kinase domain of p90 ribosomal S6 kinase 2 (RSK2)
分子名称: Ribosomal protein S6 kinase alpha-3, SODIUM ION
著者Tereshko, V, Malakhova, M, Dong, Z.
登録日2007-07-27
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2.
Nat.Struct.Mol.Biol., 15, 2008
3KN6
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BU of 3kn6 by Molmil
Crystal structure of the C-terminal kinase domain of MSK1
分子名称: Ribosomal protein S6 kinase alpha-5
著者D'Angelo, I, Malakhova, M, Dong, Z.
登録日2009-11-12
公開日2010-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of the active form of the C-terminal kinase domain of mitogen- and stress-activated protein kinase 1.
J.Mol.Biol., 399, 2010
3KN5
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Crystal structure of the C-terminal kinase domain of msk1 in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-5
著者D'Angelo, I, Malakhova, M, Dong, Z.
登録日2009-11-12
公開日2010-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of the active form of the C-terminal kinase domain of mitogen- and stress-activated protein kinase 1.
J.Mol.Biol., 399, 2010
4N0S
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BU of 4n0s by Molmil
Complex of ERK2 with caffeic acid
分子名称: CAFFEIC ACID, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
著者Kurinov, I, Malakhova, M.
登録日2013-10-02
公開日2014-08-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7992 Å)
主引用文献Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis.
Cancer Prev Res (Phila), 7, 2014
3SA0
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Complex of ERK2 with norathyriol
分子名称: Mitogen-activated protein kinase 1, SULFATE ION, norathyriol
著者Kurinov, I, Malakhova, M.
登録日2011-06-02
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5947 Å)
主引用文献Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases.
Cancer Res., 72, 2012
4ZXT
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Complex of ERK2 with catechol
分子名称: AMMONIUM ION, CATECHOL, Mitogen-activated protein kinase 1, ...
著者Kurinov, I, Malakhova, M.
登録日2015-05-20
公開日2016-05-25
最終更新日2016-10-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer.
Oncotarget, 7, 2016
5WP1
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Complex of ERK2 with 5,7-dihydroxychromone
分子名称: 5,7-dihydroxy-4H-1-benzopyran-4-one, BENZOIC ACID, Mitogen-activated protein kinase 1, ...
著者Kurinov, I, Malakhova, M.
登録日2017-08-03
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Multiple phytochemicals at low doses accumulatively inhibit one key protein in cancers
To Be Published
1SBX
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BU of 1sbx by Molmil
Crystal structure of the Dachshund-homology domain of human SKI
分子名称: Ski oncogene
著者Wilson, J.J, Malakhova, M, Zhang, R, Joachimiak, A, Hegde, R.S.
登録日2004-02-11
公開日2004-05-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of the Dachshund Homology Domain of human SKI
Structure, 12, 2004
3G51
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Structural diversity of the active conformation of the N-terminal kinase domain of p90 ribosomal S6 kinase 2
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-3
著者Kurinov, I.
登録日2009-02-04
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2
Plos One, 4, 2009

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