1HG0
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2NLF
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2NLD
| Human beta-defensin-1 (Mutant Gln11Ala) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLB
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2NLG
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2NLQ
| Human beta-defensin-1 (Mutant Lys31Ala) | Descriptor: | Beta-defensin 1, GLYCEROL, GLYCINE, ... | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLE
| Human beta-defensin-1 (Mutant Gln11Ala) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLH
| Human beta-defensin-1 (Mutant GLN24ALA) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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2NLP
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2NLS
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2NLC
| Human beta-defensin-1 (mutant Ser8Ala) | Descriptor: | ACETATE ION, Beta-defensin 1, SULFATE ION | Authors: | Lubkowski, J, Pazgier, M. | Deposit date: | 2006-10-20 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Studies of the Biological Properties of Human beta-Defensin 1. J.Biol.Chem., 282, 2007
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4TWE
| Structure of ligand-free N-acetylated-alpha-linked-acidic-dipeptidase like protein (NAALADaseL) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Tykvart, J, Barinka, C, Lubkowski, J, Sacha, P, Konvalinka, J. | Deposit date: | 2014-06-30 | Release date: | 2015-03-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and biochemical characterization of a novel aminopeptidase from human intestine. J.Biol.Chem., 290, 2015
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7R6A
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7R6B
| Crystal structure of mutant R43D/L124D/R125A/C273S of L-Asparaginase I from Yersinia pestis | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, L-asparaginase I | Authors: | Strzelczyk, P, Wlodawer, A, Lubkowski, J. | Deposit date: | 2021-06-22 | Release date: | 2022-07-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | The dimeric form of bacterial l-asparaginase YpAI is fully active. Febs J., 290, 2023
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7R69
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4FIV
| FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130 | Descriptor: | 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE, FELINE IMMUNODEFICIENCY VIRUS PROTEASE | Authors: | Kervinen, J, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A. | Deposit date: | 1998-07-15 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7, 1998
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4MCR
| A high resolution structure of human glutamate carboxypeptidase II (GCPII) in complex with folyltri-gamma-L-glutamic acid (pteroyltetra-gamma-L-glutamic acid) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Navratil, M, Barinka, C, Lubkowski, J. | Deposit date: | 2013-08-21 | Release date: | 2014-06-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and biochemical characterization of the folyl-poly-gamma-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II. Febs J., 281, 2014
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4MCP
| A high resolution structure of human glutamate carboxypeptidase II (GCPII) in complex with folyl-gamma-L-glutamic acid (pteroyldi-gamma-L-glutamic acid) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Navratil, M, Barinka, C, Lubkowski, J. | Deposit date: | 2013-08-21 | Release date: | 2014-06-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and biochemical characterization of the folyl-poly-gamma-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II. Febs J., 281, 2014
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2FMB
| EIAV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130 | Descriptor: | 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE, EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE | Authors: | Kervinen, J, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A. | Deposit date: | 1998-07-13 | Release date: | 1999-01-13 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7, 1998
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3IWW
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2FIV
| Crystal structure of feline immunodeficiency virus protease complexed with a substrate | Descriptor: | ACE-ALN-VAL-STA-GLU-ALN-NH2, FELINE IMMUNODEFICIENCY VIRUS PROTEASE, SULFATE ION | Authors: | Schalk-Hihi, C, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A. | Deposit date: | 1997-07-21 | Release date: | 1997-11-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor. Biochemistry, 36, 1997
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8ECE
| E. coli L-asparaginase II mutant (V27T) in complex with L-Glu | Descriptor: | 1,2-ETHANEDIOL, GLUTAMIC ACID, L-asparaginase 2 | Authors: | Strzelczyk, P, Wlodawer, A, Lubkowski, J. | Deposit date: | 2022-09-01 | Release date: | 2022-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | The E. coli L-asparaginase V27T mutant: structural and functional characterization and comparison with theoretical predictions. Febs Lett., 596, 2022
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8ECD
| E. coli L-asparaginase II mutant (V27T) in complex with L-Asp | Descriptor: | 1,2-ETHANEDIOL, ASPARTIC ACID, CITRIC ACID, ... | Authors: | Strzelczyk, P, Wlodawer, A, Lubkowski, J. | Deposit date: | 2022-09-01 | Release date: | 2022-11-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The E. coli L-asparaginase V27T mutant: structural and functional characterization and comparison with theoretical predictions. Febs Lett., 596, 2022
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4ECA
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1R1G
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