6UH3
 
 | | Crystal structure of bacterial heliorhodopsin 48C12 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Heliorhodopsin, PALMITIC ACID, ... | | 著者 | Lu, Y, Zhou, X.E, Gao, X, Xia, R, Xu, Z, Wang, N, Leng, Y, Melcher, K, Xu, H.E, He, Y. | | 登録日 | 2019-09-26 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of heliorhodopsin 48C12.
Cell Res., 30, 2020
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5WZX
 | | Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of FXR | | 分子名称: | (4aR,6aR,6aS,6bS,8aS,9R,12aR,14bR)-2,2,6a,6b,9,12a-hexamethyl-10-oxidanylidene-1,3,4,5,6,6a,7,8,8a,9,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid, (R,R)-2,3-BUTANEDIOL, Bile acid receptor, ... | | 著者 | Lu, Y, Li, Y. | | 登録日 | 2017-01-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity
Mol. Pharmacol., 93, 2018
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5VHR
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHN
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHJ
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHQ
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHO
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHM
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHP
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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3K3P
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5VHF
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 10, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VGZ
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-12 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHI
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 10, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHH
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 10, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5VHS
 | | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... | | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | | 登録日 | 2017-04-13 | | 公開日 | 2017-08-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
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5Y44
 | | A novel moderator XD4 for bile acid receptor | | 分子名称: | Bile acid receptor, Peptide from Nuclear receptor coactivator 1, SULFATE ION, ... | | 著者 | Lu, Y, Li, Y. | | 登録日 | 2017-08-01 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A novel moderator XD4 for bile acid receptor
To Be Published
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5Y1J
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5Y49
 | | A moderator XD22 binding to bile acid receptor | | 分子名称: | Bile acid receptor, Peptide from Nuclear receptor coactivator 2, [(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl] 4-azanylbenzoate | | 著者 | Lu, Y, Li, Y. | | 登録日 | 2017-08-02 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A moderator XD22 binding to bile acid receptor
To Be Published
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5XQ5
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5IAW
 | | Novel natural FXR modulator with a unique binding mode | | 分子名称: | (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 4-hydroxybenzoate, Bile acid receptor, Peptide from Nuclear receptor coactivator 2 | | 著者 | Lu, Y, Li, Y. | | 登録日 | 2016-02-22 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly
Chembiochem, 18, 2017
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5ICK
 | | A unique binding model of FXR LBD with feroline | | 分子名称: | (1S,2S,3Z,5S,8Z)-5-hydroxy-5,9-dimethyl-2-(propan-2-yl)cyclodeca-3,8-dien-1-yl 4-hydroxybenzoate, Bile acid receptor, Nuclear receptor coactivator 2 | | 著者 | Lu, Y, Li, Y. | | 登録日 | 2016-02-23 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly
Chembiochem, 18, 2017
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8K45
 | | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nb4 nanobody, ... | | 著者 | Lu, Y, Gao, Y, Yao, H, Xu, W, Yang, H. | | 登録日 | 2023-07-17 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
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8K47
 | | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y, Gao, Y, Yao, H, Xu, W, Yang, H. | | 登録日 | 2023-07-17 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
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8K46
 | | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses including all major Omicron strains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Lu, Y, Gao, Y, Yao, H, Xu, W, Yang, H. | | 登録日 | 2023-07-17 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains.
MedComm (2020), 4, 2023
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4FQ7
 | | Crystal structure of the maleate isomerase Iso from Pseudomonas putida S16 | | 分子名称: | Maleate cis-trans isomerase | | 著者 | Lu, Y, Chen, D, Zhang, Z, Li, Q, Wu, G, Xu, P. | | 登録日 | 2012-06-25 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and computational studies of the maleate isomerase from Pseudomonas putida S16 reveal a breathing motion wrapping the substrate inside.
Mol.Microbiol., 87, 2013
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