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1ERI
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BU of 1eri by Molmil
X-RAY STRUCTURE OF THE DNA-ECO RI ENDONUCLEASE-DNA RECOGNITION COMPLEX: THE RECOGNITION NETWORK AND THE INTEGRATION OF RECOGNITION AND CLEAVAGE
Descriptor: DNA (5'-D(*TP*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), PROTEIN (ECO RI ENDONUCLEASE (E.C.3.1.21.4))
Authors:Kim, Y, Grable, J.C, Love, R, Greene, P.J, Rosenberg, J.M.
Deposit date:1994-05-18
Release date:1995-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing.
Science, 249, 1990
1VRX
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BU of 1vrx by Molmil
Endocellulase e1 from acidothermus cellulolyticus mutant y245g
Descriptor: ENDOCELLULASE E1 FROM A. CELLULOLYTICUS
Authors:Baker, J.O, McCarley, J.R, Lovett, R, Yu, C.H, Adney, W.S, Rignall, T.R, Vinzant, T.B, Decker, S.R, Sakon, J, Himmel, M.E.
Deposit date:2005-06-30
Release date:2005-07-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catalytically enhanced endocellulase Cel5A from Acidothermus cellulolyticus.
Appl.Biochem.Biotechnol., 121-124, 2005
2ABX
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BU of 2abx by Molmil
THE CRYSTAL STRUCTURE OF ALPHA-BUNGAROTOXIN AT 2.5 ANGSTROMS RESOLUTION. RELATION TO SOLUTION STRUCTURE AND BINDING TO ACETYLCHOLINE RECEPTOR
Descriptor: ALPHA-BUNGAROTOXIN
Authors:Love, R, Stroud, R.
Deposit date:1986-02-19
Release date:1986-05-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of alpha-bungarotoxin at 2.5 A resolution: relation to solution structure and binding to acetylcholine receptor.
Protein Eng., 1, 1986
2HAI
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BU of 2hai by Molmil
Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.
Descriptor: (6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE, HEPATITIS C VIRUS NS5B RNA POLYMERASE
Authors:Li, H, Love, R.L.
Deposit date:2006-06-12
Release date:2006-09-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2I0E
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BU of 2i0e by Molmil
Structure of catalytic domain of human protein kinase C beta II complexed with a bisindolylmaleimide inhibitor
Descriptor: 3-{1-[3-(DIMETHYLAMINO)PROPYL]-2-METHYL-1H-INDOL-3-YL}-4-(2-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, Protein Kinase C-beta II
Authors:Grodsky, N.B, Love, R.L.
Deposit date:2006-08-10
Release date:2006-11-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Catalytic Domain of Human Protein Kinase C beta II Complexed with a Bisindolylmaleimide Inhibitor
Biochemistry, 45, 2006
4H6J
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BU of 4h6j by Molmil
Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction.
Descriptor: ARYL HYDROCARBON NUCLEAR TRANSLOCATOR, HYPOXIA INDUCIBLE FACTOR 1-ALPHA
Authors:Cardoso, R, Love, R.A, Nilsson, C, Bergqvist, S, Nowlin, D, Yan, J, Liu, K, Zhu, J, Chen, P, Deng, Y.-L, Dyson, H.J, Greig, M.J, Brooun, A.
Deposit date:2012-09-19
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Protein Sci., 21, 2012
1PI2
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BU of 1pi2 by Molmil
REACTIVE SITES OF AN ANTICARCINOGENIC BOWMAN-BIRK PROTEINASE INHIBITOR ARE SIMILAR TO OTHER TRYPSIN INHIBITORS
Descriptor: BOWMAN-BIRK INHIBITOR (PI-II)
Authors:Chen, P, Rose, J, Wang, B.C.
Deposit date:1991-03-26
Release date:1992-04-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Reactive sites of an anticarcinogenic Bowman-Birk proteinase inhibitor are similar to other trypsin inhibitors.
J.Biol.Chem., 267, 1992
8A3B
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BU of 8a3b by Molmil
Cryo-EM structure of mouse Pannexin 1 purified in Salipro nanoparticles
Descriptor: Pannexin-1
Authors:Drulyte, I.
Deposit date:2022-06-07
Release date:2023-02-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Direct cell extraction of membrane proteins for structure-function analysis.
Sci Rep, 13, 2023
3LOX
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BU of 3lox by Molmil
HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound
Descriptor: (1R,2S,5S)-N-[(2S,3R)-4-amino-1-cyclobutyl-3-hydroxy-4-oxobutan-2-yl]-6,6-dimethyl-3-{3-methyl-N-[(1-methylcyclohexyl)c arbamoyl]-L-valyl}-3-azabicyclo[3.1.0]hexane-2-carboxamide, BETA-MERCAPTOETHANOL, HCV NS3 Protease, ...
Authors:Prongay, A.J.
Deposit date:2010-02-04
Release date:2011-02-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.
Bioorg.Med.Chem.Lett., 20, 2010

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